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  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature structural & molecular biology 14 (2007), S. 880-882 
    ISSN: 1545-9985
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] SNARE proteins are central components of a conserved machinery that governs most types of intracellular membrane fusion in organisms ranging from yeast to mammals. Studies of the neuronal SNAREs that control neurotransmitter release, namely the synaptic vesicle protein synaptobrevin (also known as ...
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature structural & molecular biology 11 (2004), S. 844-849 
    ISSN: 1545-9985
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] The neuronal protein synaptotagmin 1 functions as a Ca2+ sensor in exocytosis via two Ca2+-binding C2 domains. The very similar synaptotagmin 4, which includes all the predicted Ca2+-binding residues in the C2B domain but not in the C2A domain, is also thought to function as a neuronal Ca2+ sensor. ...
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  • 3
    Electronic Resource
    Electronic Resource
    Bognor Regis [u.a.] : Wiley-Blackwell
    ISSN: 0887-624X
    Keywords: 1-pentene ; cationic polymerization ; microstructure ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: No abstract.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 4
    facet.materialart.
    Unknown
    Nature Publishing Group (NPG)
    Publication Date: 2014-08-22
    Description: Resonant excitations of confined systems have aroused much attention because of their potential application in future microwave devices and spintronics. Under resonant excitations, the motion of topo-logical objects exhibits circular, elliptical or even stadium-like dynamics. However, more complex non-linear resonant excitations of topological objects in confined systems have seldom been reported and the associated physical mechanism remains unclear. Here, we present an observation of flower-like resonant excitations for coupled skyrmions in Co/Ru/Co nanodisks activated by a single-frequency microwave magnetic field by means of numerical simulation. We find that flower-like dynamics of coupled skyrmions is always accompanied by an excitation of an eigenfrequency near 1.15 GHz, which is strongly associated with the large non-local deformation of the topological density distribution of coupled skyrmions. These results distinguish a skyrmion from other topological objects in dynamics and will be instrumental to the manipulation of skyrmions for applications. Scientific Reports 4 doi: 10.1038/srep06153
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
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  • 5
    facet.materialart.
    Unknown
    Nature Publishing Group (NPG)
    Publication Date: 2013-07-31
    Description: Recently, a highly dangerous bird flu has infected over 130 patients in China, and the outbreak was attributed to a novel avian-origin H7N9 virus. Here, we performed a systematic analysis of the virus. We clarified the controversial viewpoint on neuraminidase (NA) origin and confirmed it was reassorted from Korean wild birds with higher confidence, whereas common ancestors of pathogenic H7N9 genes existed only one or two years ago. Further analysis of NA sequences suggested that most variations are not drug resistant and current drugs are still effective for the therapy. We also identified a potentially optimal 9-mer epitope, which can be helpful for vaccine development. The interaction of hemagglutinin (HA) and human receptor analog was confirmed by structural modeling, while NA might influence cellular processes through a PDZ-binding motif. A simplified virus infection model was proposed. Taken together, our studies provide a better understanding of the newly reassorted H7N9 viruses. Scientific Reports 3 doi: 10.1038/srep02318
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
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