B2 RNA binds directly to RNA polymerase II to repress transcript synthesis
Nature Publishing Group
Nature Archives 1869 - 2009
[Auszug] B2 RNA is a small noncoding RNA polymerase III transcript that represses mRNA transcription in response to heat shock in mouse cells. Here we define the mechanism by which B2 RNA inhibits RNA polymerase II (Pol II) transcription. Using a purified Pol II transcription system, we found that B2 RNA ...
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