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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Banking and Finance 14 (1990), S. 199-214 
    ISSN: 0378-4266
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Economics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of fish diseases 26 (2003), S. 0 
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Bacterial cells of the marine fish pathogen Photobacterium damsela subsp. piscicida were grown in novel culture media. A mixture of whole cells and extracellular components was inactivated and used in bath, intraperitoneal (i.p.) and oral vaccination of sea bass, Dicentrarchus labrax, employing two sizes of fish. A commercial vaccine was used for comparative purposes. Control and immunized fish were either bath or intraperitoneally challenged 6 and 12 weeks post-vaccination. Small fish had significantly higher relative percentage survival with the novel vaccine mixture both at 6 and 12 weeks post-vaccination by bath, in comparison with the commercial vaccine. No protection was afforded at 6 or 12 weeks post-immunization by either vaccine after challenge via i.p. injection. Sea bass (1.5–2 g) intraperitoneally vaccinated with various adjuvanted vaccine mixtures were not protected against pasteurellosis. In contrast, larger sea bass (20 g) benefited from vaccination with the novel vaccine mixtures. Intraperitoneal challenge with the pathogen resulted in protection in both fish groups vaccinated with novel vaccine mixtures, whereas control fish suffered high mortalities (〉80%). Orally vaccinated fish were immersion challenged with the pathogen. At 6 and 12 weeks post-vaccination the control fish had a high mortality and the fish vaccinated with the novel vaccine mixture achieved good protection.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of fish diseases 26 (2003), S. 0 
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Photobacterium damsela ssp. piscicida (Phdp) isolates were grown in various bacteriological media, in eukaryotic cell culture media and in the presence of fish cells (resembling some aspects of in vivo growth environments). Bacterial cells, extracellular products (ECPs) and crude capsular polysaccharide were isolated and analysed by electrophoresis and Western blot using sea bass sera. Growth in bacteriological media conserved the synthesis of cell and extracellular components when these were compared with those prepared under near-in vivo growth conditions. In fact, synthesis of a larger range of cell components was induced after growth in bacteriological media. Certain media based on yeast extract and peptones from various sources and a specific salt formulation induced the synthesis of novel cell components at approximately 21.3 and 14 kDa. These antigens were recognized by sea bass sera collected after natural pasteurellosis outbreaks and other sea bass sera raised against live or inactivated Phdp cells. The ECPs of the pathogen were not good immunogens in their soluble form despite various treatments prior to immunization. The results are discussed with respect to vaccine development.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of fish diseases 27 (2004), S. 0 
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Photobacterium damsela subsp. piscicida, the causative agent of fish pasteurellosis, was grown in vivo. Bacterial cells and extracellular products (ECPs) were analysed via electrophoresis and immunoblot analysis, using specific sea bass antisera. Growth in vivo induced the synthesis of unique bacterial cell proteins at 〉206, 206, 21.3, 18, 7.6 and 〈7.6 kDa. Sea bass serum raised against live bacterial cells of the pathogen and especially a sea bass serum raised against formalin-inactivated bacterial cells grown in a specific novel medium recognized the novel antigens at 〉206 (associated with iron sequestration), 21.3, 7.6 and 〈7.6 kDa, suggesting that the latter medium conserves the synthesis of natural bacterial cell proteins in vitro. In vivo growth of the pathogen induced the synthesis of more toxic ECPs in comparison with in vitro growth and an inverse correlation between total protein concentration in the ECPs and toxicity per unit of protein was observed. Substrate-polyacrylamide electrophoresis revealed the presence of in vivo synthesized ECPs of the pathogen (proteases) at 175, 132, 〈79 and 48.3 kDa. Histological examination of tissues isolated from fish injected with these ECPs revealed inflammatory and necrotic lesions in the spleen, liver, head kidney, intestine and heart as soon as 48 h post-introduction of the ECPs.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Infrared Physics 18 (1978), S. 1-5 
    ISSN: 0020-0891
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Decisions in economics and finance 13 (1990), S. 111-131 
    ISSN: 1129-6569
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Economics
    Description / Table of Contents: Riassunto Si considera una versione modificata del modello di crescita non-lineare di Goodwin, in cui il reddito,Y, è una funzione quadratica dello stock di capitale,k, così da permettere la possibilità di rendimenti crescenti o decrescenti. La dinamica del modello viene allora rappresentata da un sistema non autonomo di due equazioni differenziali. Con l'ipotesi che l'offerta di lavoro,N, e la produttività,a, siano costanti nel tempo, il modello diventa autonomo e può essere immerso in una famiglia stabile di sistemi dinamici piani, di cui vengono descritti i flussi globali e le biforcazioni.
    Notes: Abstract We consider a modified version of Goodwin's celebrated non-linear model of fluctuating growth, where the incomeY is a quadratic function of the capital stockk, in order to take into account the possibility of increasing or decreasing returns. The dynamics of the model is then defined by a non-autonomous system of two differential equations. Assuming the labour supply,N, and the productivity,a, to be constant in the time, the model becomes autonomous and can be embedded in a stable family of planar dynamical systems whose flows and bifurcations are globally described
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Decisions in economics and finance 13 (1990), S. 133-145 
    ISSN: 1129-6569
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Economics
    Description / Table of Contents: Riassunto Un modello non-lineare di crescita alla Goodwin, in cui i rendimenti possono essere non costanti, è rappresentato da un sistema dinamico piano non autonomo, che può essere trasformato in un sistema autonomo tridimensionale. Viene descritto il comportamento globale di quest'ultimo nei due casi di rendimenti crescenti o decrescenti. Si dimostra, in particolare, l'assenza di attrattori economicamente significativi ed il diverso carattere delle orbite: mentre, se i rendimenti sono crescenti, le traiettorie convergono asintoticamente ad un punto singolare dove “l'economia muore”, nel caso opposto le traiettorie sono illimitate e spiraleggiano intomo ad una retta che ha la direzione dell'assek (la variabile di stato che rappresenta lo stock di capitale).
    Notes: Abstract The dynamics of a model of fluctuating growth, where non-constant returns are allowed, is represented, under Goodwin's classical assumptions, by a non-autonomous two-dimensional system, which can be transformed into an autonomous three-dimensional one. We describe the global phase portrait of the latter, in the two cases of increasing and decreasing returns, proving, in particular, the absence of economically meaningful “attractors”. However the orbits exhibit different features in the two cases: namely they asymptotically converge to a singular point, where “the economy dies”, if the returns are decreasing, and diverge, spiralling around a certain line, if the returns are increasing.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Neurological sciences 16 (1995), S. 487-492 
    ISSN: 1590-3478
    Keywords: Guillain-Barré Syndrome ; Immune globulins ; Plasma-exchange therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Riportiamo i risultati del trattamento con plasmaferesi (PE) e immunoglobuline (IVIg) in 36 su 50 pazienti con sindrome di Guillain-Barré (GBS) reclutati attraverso uno studio di incidenza condotto in Emilia-Romagna. Il confronto fra PE e IVIg non ha evidenziato differenze significative per quanto concerne la capacità di migliorare il decorso della malattia. Complessivamente, nei trattati con IVIg e PE il 25% e l'11,1% rispettivamente erano guariti ad un mese, mentre il 58,3% e il 55,5% erano migliorati di almeno un grado. Questi risultati sono in accordo con le conclusioni del Dutch GBS Trial per ciò che concerne l'outcome a un mese. Nessuna ricaduta è stata osservata nei due gruppi. Inoltre, non è stata osservata nessuna differenza nell'outcome clinico a 1 e 3 mesi tra i pazienti che ricevettero una sola o due terapie. Un secondo ciclo di terapia non sembra migliorare significativamente il decorso clinico della malattia. PE e IVIg sono entrambe sicure ed efficaci nella terapia della GBS.
    Notes: Abstract We report the effects of treatment with plasma-exchange (PE) and intravenous immune globulins (IVIg) in 36 out of 50 patients with Guillain-Barré syndrome (GBS) recruited by an incidence study in the Emilia-Romagna region of Italy. Comparison of the patients treated with PE and IVIg showed no significant differences in terms of effectiveness in improving the clinical course of GBS: at one month, respectively 11.1% and 25% had recovered, and 55.5% and 58.3% had improved by at least one grade. These results are in agreement with those of the Dutch GBS trial. No relapses were observed in either group. Moreover, our results showed no difference in clinical outcome at 1 and 3 months between the patients receiving only one therapy and those receiving two; a second cycle of therapy did not seem to improve the clinical course of the disease significantly. We conclude that PE and IVIg are both safe and effective therapies for GBS.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Journal of economics 65 (1997), S. 103-121 
    ISSN: 1617-7134
    Source: Springer Online Journal Archives 1860-2000
    Topics: Economics
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of applied ichthyology 14 (1998), S. 0 
    ISSN: 1439-0426
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: The present research studied the effects of feeding diets containing different doses of glucan on stress prevention in rainbow trout (Oncorhynchus mykiss). Different concentrations of glucan (0, 0.1, 0.5 or 1.0%) were administered to the fish over a 4-week period, then the fish were stressed by being transported for 2h. The effect of stress on the efficiency of the immune response was studied by measuring alterations of the following parameters: number and composition of the leucocyte population, phagocytosis and respiratory burst activity. At the end of the treatment, glucan-fed trout had increased levels of phagocytosis and oxidative radical production, but the data could not be correlated with the different dietary concentrations of glucan. Respiratory burst and phagocytosis appeared significantly reduced in stressed groups. The reduction was more evident in the control group, but no differences were detected between groups fed different diets. Transportation stress increased phagocytosis activity, but for control fish and fish fed 1.0% glucan it did not reach the levels observed before stress. Feeding glucan apparently induced a slight degeneration of the epithelial cells in the stomach and gut mucosae.
    Type of Medium: Electronic Resource
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