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  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature America Inc.
    Nature medicine 5 (1999), S. 1231-1232 
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Two papers suggest that apoptosis of alloreactive T cells is required for induction of peripheral transplantation tolerance. These findings raise new questions about how lymphocytes reach from beyond the grave to influence the immune response (pages 1298–1302 and ...
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature medicine 3 (1997), S. 1117-1123 
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] The HIV-1 accessory gene product Vpr can influence viral pathogenesis by affecting viral replication as well as host cell transcription and proliferation. We have investigated the effects of Vpr on host cell activation and confirm that it influences cellular proliferation. However, we have also ...
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 373 (1995), S. 441-444 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] To address the possible role of Fas/Fas-ligand interactions in activation-induced apoptosis in T-cell hybridomas, we examined the expression of Fas and Fas-ligand in the hybridoma line Al. 1, which rapidly undergoes apoptosis following activation1'3. Al.l cells do not express cell-surface Fas ...
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 313 (1985), S. 400-402 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Hydractinia echinata is an athecate colonial marine hydroid possessing a genetically based capacity for discrimination between related and unrelated colonies of the same species6-9. Colonies are composed of an ectodermal mat from which arise many feeding polyps (each superficially similar to those ...
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 339 (1989), S. 625-626 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] It has been suggested that AICD in thymocytes may be the mechanism by which autoreactive clones become negatively selected during T-cell development11. As CsA has been shown to interfere with the process of negative selection in the thy-mus5'6, we asked whether CsA blocks AICD. We first examined ...
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  • 6
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 320 (1986), S. 451-454 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Prolonged oral immunization of C3H/HeN mice with SRBC induces systemic unresponsiveness, while identically treated C3H/HeJ mice exhibit IgM, IgG and IgA anti-SRBC splenic plaque-forming cell (PFC) responses (Fig. I)3. The inability to induce oral tolerance in C3H/HeJ mice is linked to a defective ...
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  • 7
    Electronic Resource
    Electronic Resource
    [s.l.] : Macmillan Magazines Ltd.
    Nature 405 (2000), S. 28-29 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Multicellular animals are confronted daily with death and its consequences, at least at the cellular level. Cells die from wear and tear, as a part of differentiation and selection, and through mechanisms that provide for normal cellular turnover. Cells usually die by apoptosis, a death process ...
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  • 8
    Electronic Resource
    Electronic Resource
    [s.l.] : Macmillan Magazines Ltd.
    Nature 396 (1998), S. 629-630 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The simple fact that cancer cells survive beyond their normal ‘die by’ date has only in the past decade been incorporated into our understanding of tumorigenesis. How transformed cells evade death provides insights not only into cancer, but also into the molecular mechanisms of ...
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  • 9
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 450 (2007), S. 1253-1257 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Phagocytosis and autophagy are two ancient, highly conserved processes involved, respectively, in the removal of extracellular organisms and the destruction of organisms in the cytosol. Autophagy, for either metabolic regulation or defence, involves the formation of a double membrane called ...
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  • 10
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 412 (2001), S. 133-135 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In all animals, the process of programmed cell suicide (apoptosis) is coordinated by enzymes known as caspases, which cut up key substrates in the cell. The dying cell is then neatly packaged, engulfed by neighbouring 'phagocytic' cells, and cleared from the body without fanfare, leaving no ...
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