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  • 1
    Online Resource
    Online Resource
    San Diego : Academic Press
    Keywords: Multivariate Analyse ; Multivariate analysis ; Multivariate Analyse
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (xiii, 376 p.) , ill , 24 cm
    Edition: Rev. ed
    ISBN: 0121609545 , 9780121609542
    DDC: 519.5/35
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    Language: English
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  • 2
    Book
    Book
    Stuttgart : Poeschel
    Keywords: Marketingforschung ; Marktforschung ; Marketing research ; Marketingforschung ; Marktforschung
    Type of Medium: Book
    Pages: XIV, 632 S. , Ill., graph. Darst.
    Edition: 4. Aufl.
    ISBN: 3791003445 , 3791003348
    Uniform Title: Research for marketing decisions
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    Language: German
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science, Ltd
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The mechanism by which chronic stress affects the course of inflammatory diseases is still not well understood. We have evaluated the effect of two types of nonhabituating stress on a major component of the inflammatory response, synovial plasma extravasation, induced by perfusion of the potent inflammatory mediator, bradykinin and evaluated the underlying neuroendocrine mechanism in the rat. Chronic intermittent noise or ether stress induced profound inhibition of bradykinin-induced plasma extravasation, which is associated with increased adjuvant-arthritis severity. This inhibition, however, took 24 h to fully develop after the last exposure to stress and persisted for at least 48 h. The inhibition could be reversed by an additional exposure to the stressor, just prior to measuring the inflammatory response, suggesting that the delay is due to stress-induced release of a factor that acutely masks the inhibition of the inflammatory response. This novel, unexpected feature of the effect of nonhabituating stress on inflammation may help explain variability in effects of stress in patients with inflammatory disease. The effect of nonhabituating stress on inflammation was dependent on the sympathoadrenal axis with no detectable contribution by the hypothalamic–pituitary–adrenal axis.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Epinephrine produces sexually dimorphic β2-adrenergic receptor-mediated mechanical hyperalgesia, with male rats exhibiting greater hyperalgesia. Because female rats have higher plasma epinephrine levels, and β-adrenergic receptor sensitivity is affected by chronic exposure to agonists, we tested the hypothesis that this sexual dimorphism is due to epinephrine-induced desensitization of β2-adrenergic receptors. Following gonadectomy, epinephrine hyperalgesia, as measured by the Randall–Selitto paw-withdrawal test, was unchanged in male rats while in females it was increased. Prepubertal male and female rats do not demonstrate sexual dimorphism in either plasma epinephrine level or epinephrine-induced hyperalgesia. Adrenal medullectomy and adrenal denervation both significantly enhanced epinephrine hyperalgesia, but only in females. In contrast, the sexually dimorphic hyperalgesia induced by prostaglandin E2, another agent that acts directly to sensitize primary afferent nociceptors, was not enhanced by adrenal medullectomy or denervation. Chronic administration of epinephrine in male rats, to produce plasma levels similar to those of gonad-intact females, significantly attenuated epinephrine-induced hyperalgesia, making it similar to that in females. These results strongly support the suggestion that estrogen regulates plasma epinephrine in female rats and differential sensitivity to β2-adrenergic agonists accounts for the sexual dimorphism in epinephrine-induced hyperalgesia. Unexpectedly, regulation of adrenal medullary function by estrogen was also found to modulate baseline nociceptive threshold such that females had a lower nociceptive threshold.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Communications in mathematical physics 109 (1987), S. 99-108 
    ISSN: 1432-0916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Notes: Abstract We consider constructions of manifolds withSU(3) holonomy as embedded in products of complex projective spaces by imposing certain homogeneous holomorphic constraints. We prove that every such construction leads to one deformation class of manifolds withSU(3) holonomy. For a subset of these manifolds we prove simple connectedness, address the problem of calculating the second Betti number and explicitly calculate it for a class of constructions. This establishes a very wide class of manifolds withSU(3) holonomy, that can give rise to yet many more constructions via dividing out the action of suitably chosen discrete groups. Some of the examples studied may yield phenomenologically acceptable models.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Communications in mathematical physics 119 (1988), S. 431-441 
    ISSN: 1432-0916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Notes: Abstract We demonstrate that many families of Calabi-Yau threefolds consist generically of small resolutions of nodal forms in other families and, in fact, that a large class of families is connected by this relation. Our result resonates with a conjecture of Reid that Calabi-Yau threefolds may have a universal moduli space even though they are of different homotopy types. Such ideas tie quite naturally to alluring prospects of unifying (super)string models.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    ISSN: 1600-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract Loss of attachment as measured by a portion of Ramfjord's Index (PDI) was determined in 383, 12–16-year-old schoolchildren in rural Juniata County, PA. Prevalence and distributions were tabulated for sex, last dental visit, and type of treatment received. Denial knowledge test scores, toothbrushing effectiveness, periodontal status and oral cleanliness were determined at annual intervals Irom Spring '75 to Spring '79. Mean scores were contrasted with bone loss measurements. 47.3% had loss of attachment (〉1 mm) including 24.5% with 2 mm or more of attachment loss per mouth. Females (41.0%) had significantly lower prevalence rates than males (52.7%). Students who visited a dentist in the last 6 months and who received scaling had less bone loss, lower GI, PII, PI, and QHI scores. An inverse relationship was found between dental knowledge and the other variables measured. Similar patterns were seen with high, medium and low bone loss groups. Many variables in this study were associated with bone loss, including: plaque, dental knowledge, dental behavior (toothbrushing and visiting a dental clinic), recent treatment received and sex. None appeared more significant than the others.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Bradford : Emerald
    The @journal of services marketing 17 (2003), S. 6-36 
    ISSN: 0887-6045
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Conjoint analysis is a class of techniques for analyzing consumers' preferences and trade-offs regarding their selection of products and services. Typically, conjoint analysis has been applied to established markets such as frequently purchased packaged goods, consumer durables, communication services, and business-to-business products. Recently, marketing researchers have extended conjoint methodology to cope with the measurement of buyer trade-offs associated with "really new" products and services, for which there is little or no prior buyer knowledge or experience. The researcher's task is twofold: to educate the potential buyer regarding the pros and cons of the new product/service while, at the same time, obtaining the respondent's evaluation of the new product/service itself. This article describes the application of conjoint techniques to a new service, TrafficPulse, that enables subscribers to obtain continuous 24/7 updates on traffic conditions, travel times, and alternative routes, should congestion occur. In particular, describes how traditional conjoint analysis can be embellished to obtain relevant information about consumer evaluations of new goods and services prior to their actual use by prospective consumers. In short, the prospective consumer can be "educated" about the new product/service before obtaining evaluation of its potential worth. The paper also shows how conjoint analysis can be modified to accommodate restrictions on various attribute levels, how the use of BASES-like norms can be incorporated, and how optimization algorithms can be used at either the single product or multiple product (i.e. product line) level.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature America Inc.
    Nature medicine 5 (1999), S. 1057-1061 
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Although the inflammatory response is essential for protecting tissues from injury and infection, unrestrained inflammation can cause chronic inflammatory diseases such as arthritis, colitis and asthma. Physiological mechanisms that downregulate inflammation are poorly understood. Potent ...
    Type of Medium: Electronic Resource
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