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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 136 (1997), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We report the case of a 20-year-old man, who was born with an intense erythema of the genital area, unresponsive to any treatment employed. When he was 9 months old, he presented with well-defined hyperkeratotic erythematous plaques around the mouth, eyes, nose, and perianal area, with similar plaques on the lateral aspect of the neck and axillae. At the same time the erythema of the genital area became hyperkeratotic. When he was 2 years old, he presented with a disabling palmoplantar keratoderma, initially focal, and later diffuse, also unresponsive to local or systemic treatments employed. The lesions have varied during the course of the disease without ever clearing completely. The axillary and inguinal plaques have shown spontaneous resolution on occasion. Six skin biopsies have been performed with no conclusive histological diagnosis of any of the typical disorders of keratinization. All treatments, topical and systemic, including etretinate and acitretin, have failed to improve the condition. We believe that this patient has Olmsted syndrome, a rare form of palmoplantar keratoderma with periorificial keratotic plaques.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Connectivity, the self-defined interactions between antigen-recognising molecules in a network system can in part be assessed by measuring the reactivity of a given serum against an ordered set of immunoglobulin (Ig)G F(ab′)2 fractions, separated by means of isoelectric focusing so that, the serum reactivity against the whole set of fractions defines a characteristic pattern of connectivity. Deviations from the normal condition (healthy donors) have so far been documented for two autoimmune diseases: systemic lupus erythematosus (SLE) and pemphigus vulgaris, as well as for human immundeficiency virus (HIV)-1 infection. We tested here if bacterial infections lead to alterations in connectivity. In addition, we wanted to test if two antigenically related bacteria would produce similar or otherwise distinctive connectivity patterns. Connectivity analysis was applied on the sera from tuberculosis and leprosy patients and the sera from healthy donors were used as control.No statistically significant differences between the three groups studied were found. These results have implications for theories that set the origin of autoimmune diseases in microbial infections. To the best of our knowledge, this is the first attempt to analyze the connectivity status in bacterial infections.
    Type of Medium: Electronic Resource
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  • 3
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    Unknown
    Basel: MDPI
    Publication Date: 2017-08-26
    Description: This paper considers a population of agents that are engaged in a listening network. The agents wish to match their actions to the true value of some uncertain (exogenous) parameter and to the actions of the other agents. Each agent begins with some initial information about the parameter and, in addition, is able to receive further information from their neighbors in the network. I derive a closed expression for the (interim) social welfare loss that depends on the initial information structure and on the possible pieces of information that can be gathered under the network. Then, I explore how changes in the network may affect social welfare for extreme levels of complementarity in the agents' actions. When the level of complementarity is very high, efficiency is achieved regardless of the network structure. For very low levels of complementarity in actions, efficiency can be either associated to more sparse or denser networks, depending on the size of the induced informative gains. The implications of this paper are relevant in security environments where agents are naturally interpreted as analysts who try to forecast the value of a parameter that describes a threat to security.
    Keywords: C72 ; D83 ; D84 ; D85 ; ddc:330 ; networks ; information aggregation ; beauty-contests ; strategic complementarity ; social welfare
    Language: English
    Type: doc-type:article
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  • 4
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    Unknown
    MDPI Publishing
    Publication Date: 2015-04-03
    Description: Libyan Desert Glass (LDG) is a natural silica-rich melted rock found as pieces scattered over the sand and bedrock of the Western Desert of Egypt, northeast of the Gilf Kebir. In this work, a population mixture analysis serves to relate the present spatial distribution of LDG mass density with the Late Oligocene–Early Miocene fluvial dynamics in the Western Desert of Egypt. This was verified from a spatial distribution model that was predicted from the log-normal kriging method using the LDG–mass-dependent transformed variable, Y(x). Both low- and high-density normal populations (–9.2 〈 Y(x) 〈 –3.5 and –3.8 〈 Y(x) 〈 2.1, respectively) were identified. The low-density population was the result of an ordinary fluvial LDG transport/deposition sequence that was active from the time of the melting process, and which lasted until the end of activity of the Gilf River. The surface distribution of the high-density population allowed us to restrict the source area of the melting process. We demonstrate the importance of this geostatistical study in unveiling the probable location of the point where the melting of surficial material occurred and the role of the Gilf River in the configuration of the observed strewn field.
    Electronic ISSN: 2076-3263
    Topics: Geosciences
    Published by MDPI Publishing
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  • 5
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    Unknown
    Nature Publishing Group (NPG)
    Publication Date: 2014-05-22
    Description: Article Hyperpolarized 129 Xe gas is used as a contrast agent in nuclear magnetic resonance imaging. Here, the authors demonstrate a microfluidic chip that optically polarizes 129 Xe gas for compact nuclear magnetic resonance imaging applications. Nature Communications doi: 10.1038/ncomms4908 Authors: Ricardo Jiménez-Martínez, Daniel J. Kennedy, Michael Rosenbluh, Elizabeth A. Donley, Svenja Knappe, Scott J. Seltzer, Hattie L. Ring, Vikram S. Bajaj, John Kitching
    Electronic ISSN: 2041-1723
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General , Physics
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  • 6
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    Unknown
    Hindawi
    Publication Date: 2013-03-07
    Description: The changes in SDS-PAGE proteins patterns, oligosaccharides and phenolic compounds of L. campestris seeds, were evaluated during nine germination days. SDS-PAGE pattern showed 12 bands in the original protein seeds, while in the samples after 1–9 germination days, the proteins located in the range of 28–49 and 49–80 kDa indicated an important reduction, and there was an increase in bands about 27 kDa. On the other hand, oligosaccharides showed more than 50% of decrease in its total concentration after 4 germination days; nevertheless after the fifth day, the oligosaccharides concentration increases and rises more than 30% of the original concentration. Phenolic compounds increased their concentration since the first germination day reaching until 450% more than the original seed level. The obtained results are related with liberation or increase of phenolic compounds with antioxidant properties, allowing us to suggest that the germination would be used to produce legume foods for human consumption with better nutraceutical properties.
    Print ISSN: 1687-8159
    Electronic ISSN: 1687-8167
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Published by Hindawi
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  • 7
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    Unknown
    Consejo Superior de Investigaciones Científicas (CSIC)
    Publication Date: 2013-10-04
    Description: El meteorito de Retuerta del Bullaque es un nuevo siderito español, encontrado en 1980 cerca de esta localidad de Ciudad Real, en un área colindante al Parque Nacional de Cabañeros (39º27’32”N, 4º22’39”O). Con cerca de 100 kg de peso, se trata de una octaedrita gruesa moderadamente oxidada con regmaglifos. Algunos sectores del borde están recristalizados debido a la fricción con la atmósfera. Los análisis de ICP-AES (Ni: 7.527 y Co: 0.475 en % en peso) e ICP-MS (Ga: 68.9, Ge: 365, As: 13.7, W: 0.95, Ir: 1.95 y Au: 1.70 en ppm) permiten clasificar el ejemplar en el grupo principal del complejo IAB. Químicamente, el meteorito de Retuerta del Bullaque es similar al siderito de Kaalijarv, aunque mineralógica y texturalmente es más parecido a otros sideritos del citado grupo, con menos Ni y Au (como por ejemplo Cañón del Diablo). Retuerta del Bullaque está compuesto principalmente por kamacita, tanto en bandas de Widmanstätten (2.0 ± 0.3 mm) con inclusiones de cohenita, como en sectores poligonales sin cohenita y con abundantes líneas de Neumann. En ambas zonas, la kamacita contiene schreibersita alotriomorfa e idiomorfa (rhabdita). La taenita forma delgadas lamelas situadas entre los cristales de kamacita y también dentro de plessitas perlíticas. La cohenita lamelar es muy abundante (9.5 % del área total en dos secciones de 77.7 y 41.1 cm 2 ), está parcialmente recubierta de schreibersita y contiene esférulos de kamacita y taenita. La sección más grande muestra varios nódulos de troilita- grafito (máxima dimensión: 5-18 mm), localizados en las zonas centrales de la kamacita poligonal. Cada nódulo está recubierto por schreibersita + cohenita. Hemos preservado la morfología original del ejemplar mediante técnicas de moldeo y vaciado (basadas en elastómeros, resinas y escayolas modificadas) y utilizado tecnología de escáner láser en 3D.
    Print ISSN: 0367-0449
    Electronic ISSN: 1988-3250
    Topics: Geosciences
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