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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 61 (1982), S. 279-283 
    ISSN: 1432-2242
    Keywords: Maize ; Corn ; Zea mays L. ; Recurrent selection ; General combining ability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Two-locus theory for recurrent selection for general combining ability in maize was developed. The theory featured: (a) recombination of the selfed progeny of selected parents; and (b) linkage disequilibrium in the initial gametic array. The theory indicated: (a) that initial linkage disequilibrium exerts a permanent influence upon selection progress; (b) that interposition of one or more generations of random mating before each cycle reduces the permanent effect in ensuing cycles; and (c) that random mating done before initiation of selection is more efficient in removing the influence of linkage disequilibrium on selection progress than random mating done between subsequent cycles.
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 64 (1983), S. 295-301 
    ISSN: 1432-2242
    Keywords: Corn ; Zea mays L. ; Linkage ; Reciprocal recurrent selection ; Recombination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Because each population in a reciprocal recurrent selection program can be dually described as a tester for its reciprocal and as a population subject to selection, selection progress can be partitioned into algebraic terms that are (a) unaffected by initial linkage disequilibrium, (b) modified exclusively by initial linkage disequilibrium in the selection populations, (c) influenced solely by initial linkage disequilibrium in the tester populations, and (d) modulated jointly by initial linkage disequilibrium in both populations. If only additive genetic effects are present in the intercross population, linkage disequilibrium affects selection progress via only the selection populations. Initial linkage disequilibrium affects selection progress via the tester populations, and/or the selection and tester populations jointly, only in the presence of epistatic effects for which, out of all alleles involved in the interaction, two alleles emanate from the tester population. If only additive x additive epistasis is present, initial linkage disequilibrium affects progress via both the selection and tester populations, but the effect is permanent via only the selection populations. The effect of initial linkage disequilibrium via the tester populations, and/or the selection and tester populations jointly, is permanent only in the presence of additive x dominance and/or dominance x dominance epistasis in the intercross population.
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 15 (1970), S. 97-113 
    ISSN: 1432-0533
    Keywords: Canine Herpesvirus ; Tissue Culture ; Nucleolar Segregation ; Inclusion Bodies, viral-Herpesvirus Encephalitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wurden die Auswirkungen vonHerpes canis, einem encephalitogenen Virus des Hundes, an Kleinhirnexplantaten vom Hund und an Hirzellkulturen untersucht. Ein Fortschreiten der Infektion von Zelle zu Zelle wurde an Hirnexplantatkulturen beobachtet mit dem Ergebnis einer cellulären Degeneration und ausgedehnter Nekrose innerhalb 72 Std nach der Inokulation. Astrocyten wurden als der bevorzugte Zelltyp für Virusvermehrung erkannt. Obwohl Nervenzellen unwiderruflich geschädigt waren, enthielten sie niemals eindeutig darstellbare Einschlußkörper, die auf Virusvermehrung hindeuten. Der progressive Effekt vonHerpes canis an einem neuroektodermalen Zelltyp (Astrocyten) wurde in Hirnzellkulturen untersucht, indem die Ergebnisse verschiedener Methoden, Acridinorange-Cytochemie, Immunofluorescenz sowie Licht-und Elektronenmikroskopie vergleichend ausgewertet wurden. Entsprechend dem Fortschreiten der Veränderungen in den Astrocyten wurden die Läsionen in drei Phasen eingeteilt: Die frühe Phase war durch virale Eintrittsstadien und nucleoläre Segregation gekennzeichnet, wobei sich die Pars amorpha erst von der Pars fibrosa separierte und beide Komponenten schließlich rhektisch zerfielen. Während der Mittelphase wurden drei Einschlußkörpertypen erkannt und sowohl Virusantigen als auch Viruspartikelchen in verschiedenen Stadien der Reifung in den Kernen betroffener Zellen nachgewiesen. Die späte Phase war durch Zelldegeneration und Virusentlassung in das Cytoplasma gekennzeichnet. Beidein vitro-Systeme (Hirnexplantate und Zellkulturen) boten eine ausgezeichnete Gelegenheit detaillierter und wiederholter Beobachtungen der Wechselbeziehungen eines neuropathogenen Herpesvirus mit verschiedenen neuroektodermalen Zelltypen, die dem natürlichen Wirt des Krankheitserregers entstammten. Viele Beobachtungen an den Gewebekulturen scheinen für die Pathogenese der Herpesencephalitis des Hundes von zutreffender Bedeutung zu sein.
    Notes: Summary The effects ofHerpes canis, an encephalitogenic agent of the canine species, on canine cerebellar explants and brain cell cultures were investigated. A progression of the infection from cell to cell in brain explant cultures could be followed resulting in degeneration and widespread cell death within 72 hours after inoculation. Astrocytes were recongized as the preferential cells for viral replication. Nerve cells were irreversibly damaged but manifested no definite inclusion bodies indicative of viral replication. The sequential effects ofHerpes canis on a neuroectodermal cell type (astrocytes) were studied in brain cell cultures by correlating the results of aridine orange cytochemistry and immunofluorescence with the findings of light and electron microscopy. The progression of lesions within astrocytes was divided into three phases. The early phase was characterized by viral entry and nucleolar segregation consisting of separation of the pars amorpha from the pars fibrosa which subsequently fragmented. Three forms of inclusion bodies appeared during the middle phase and viral antigen and viral particles in various stages of maturation were demonstrated within the nuclei of affected cells. The late phase consisted of cell degeneration and viral release. The twoin vitro systems (brain explants and cell cultures) offered an excellent opportunity for detailed and repeated observations of the interactions of a neuropathogenic herpes virus with the various neuroectodermal cellular elements obtained from the natural host. Many of the findings appear to be directly applicable to pathogenetic principles of canine herpes virus encephalitis.
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Computational mechanics 25 (2000), S. 245-256 
    ISSN: 1432-0924
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  This paper presents a Generalized Particle Algorithm (GPA) for high velocity impact and other dynamics problems. A velocity smoothing algorithm is also presented. This generalized algorithm allows for both variable nodal connectivity and fixed nodal connectivity. The variable connectivity option allows for severe distortions with a Lagrangian approach. With fixed nodal connectivity and smoothing it is possible to provide stable computations for large tensile strains. The algorithms are provided for 2D axisymmetric geometry and 3D geometry, and examples are included to demonstrate some of the capabilities. A discussion of interface problems and solutions is also included.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Computational mechanics 15 (1994), S. 201-223 
    ISSN: 1432-0924
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The constitutive relationships for an anisotropic material are established for shock wave propagation and nonlinear, large deformation computer programs, commonly referred to as hydrocodes. Stresses are formulated in terms of strains; the procedure for separating material compressibility effects (equation of state) from strength effects is formulated which permits the consistent calculation of stresses in the elastic regime, and allows the mean pressure to be defined in accordance with their scalar interpretations. Futher, this procedure permits the computation of inelastic response by scaling of deviatoric stresses, so the equivalent stress resides on a yield or failure surface, without changing the pressure. The procedure for computing the equivalent plastic strain and non-radial return to the yield surface, which results from a calculated overstress, is developed. Also, the transformation matrices for large deformation (rotation), necessary for transformation between material and geometric coordinates, are presented.
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  • 6
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 56 (1985), S. 264-267 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A flow visualization technique which utilized a photochromic dye in solution was introduced by Popovich and Hummel in 1967. The dye was activated along narrow trace lines by passing sharply focused beams from an ultraviolet light source through the solution. The movement of the dye traces were recorded by high-speed cinematography and velocities were found from analysis of the resulting pictures. Two variations to this basic method are described. These permit more accurate velocity measurements to be made in certain liquid systems where test volumes are small or near physical barriers, and where the flow is two dimensional or is time dependent. Manufacture of a suitable dye and construction of an inexpensive pulse laser which may be used as an ultraviolet light source are discussed.
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  • 7
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 316 (1985), S. 633-636 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] B.Ad cells were derived from B ALB/c bone marrow adherent cell cultures (see Fig. 1 legend). On reaching confluence, cultures of B.Ad cells displayed clusters of lipid-containing cells intermixed with fibroblastoid cells (Fig. 1). The lipid-containing cells were oil red O positive, and most cells ...
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  • 8
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    ISSN: 1520-5134
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 109 (1987), S. 1990-1994 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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