HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations
Nature Publishing Group
Nature Archives 1869 - 2009
[Auszug] Recruitment of the histone deacetylase (HDAC)-associated Sin3 corepressor is an obligatory step in many eukaryotic gene silencing pathways. Here we show that HBP1, a cell cycle inhibitor and regulator of differentiation, represses transcription in a HDAC/Sin3-dependent manner by targeting the ...
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