WILBERT

Wildauer Bücher+E-Medien Recherche-Tool

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Book
    Book
    München : Oldenbourg Wissenschaftsverlag GmbH
    Keywords: Derivat (Wertpapier) ; Derivat 〈Wertpapier〉
    Type of Medium: Book
    Pages: vxi, 262 S. , 24 cm
    ISBN: 9783486597448
    DDC: 332.6457
    Language: Chinese , German
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 2
    facet.materialart.
    Unknown
    BioMed Central
    Publication Date: 2015-02-28
    Description: Background: Cerebral ischemia-reperfusion injury may simultaneously result in functional variation of multiple genes/pathways. However, most prior time-sequence studies on its pathomechanism only focused on a single gene or pathway. Our study aimed to systematically analyze the time-dependent variation in the expression of multiple pathways and networks within 24 h after cerebral ischemia-reperfusion injury. Results: By uploading 374 ischemia-related genes into the MetaCore software, the variation in the expression of multiple pathways and networks in 3 h, 12 h, and 24 h after cerebral ischemia-reperfusion injury had been analyzed. The conserved TNFR1-signaling pathway, among the top 10 pathways, was consistently enriched in 3h, 12h, and 24h groups. Three overlapping pathways were found between 3h and 12h groups; 2 between 12h and 24h groups; and 1 between 3h and 24h groups. Five, 4, and 6 non-overlapping pathways were observed in 3h, 12h, and 24h groups, respectively. Apart from pathways reported by earlier studies, we identified a novel pathway related to the time-dependent development of cerebral ischemia pathogenesis. The process of apoptosis stimulation by external signals, among the top 10 processes, was consistently enriched in 3h, 12h, and 24h groups; 2, 1, and 2 processes overlapped between 3h and 12h groups, 12h and 24h groups, and 3h and 24h groups, respectively. Four, 5, and 5 non-overlapping processes were found in 3h, 12h and 24h groups, respectively. The presence of apoptotic processes was observed in all the 3 groups; while anti-apoptotic processes only existed in 3h and 12h groups. Additionally, according to node degree, network comparison identified 1, 8, and 5 important genes or proteins (e.g. Pyk2, PKC, E2F1, and VEGF-A) in 3h, 12h, and 24h groups, respectively. The Jaccard similarity index revealed a higher level of similarity between 12h and 24h groups than that between 3h and 12h groups. Conclusion: Time-dependent treatment can be utilized to reduce apoptosis, which may activate anti-apoptotic pathways within 12 h after cerebral ischemia-reperfusion injury. Pathway and network analyses may help identify novel pathways and genes implicated in disease pathogenesis.
    Electronic ISSN: 1752-0509
    Topics: Biology
    Published by BioMed Central
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 3
    facet.materialart.
    Unknown
    MDPI Publishing
    Publication Date: 2016-10-25
    Description: This study attempted to explore how informed choice on contraceptive methods influenced induced abortions among reproductive-age immigrant women in China. A total of 3230 participants were recruited in Beijing, Shanghai, and Chongqing. Information on informed choice was collected by questionnaires. The annual incidence rate (spells) of induced abortions was 0.46 (1500/3230) among the participants. The sequence from the highest score to the lowest was long-term, short-term and natural contraceptive methods (p 〈 0.0001). Significant differences of rates in induced abortions were found in region, occupation, length of the first immigration up to now (year), purpose for immigration, number of children, marital status, sex preference, contraceptive methods, deciders of contraceptive methods and side effects. In the zero-inflated negative binomial model, the joint impacts showed when a participant with one child employed condoms or family planning service providers as the deciders of contraceptive methods introduced intrauterine devices, the occurrence of induced abortions was more likely to be reduced. Women who underwent side effects using pills were more likely to have had induced abortions.
    Print ISSN: 1661-7827
    Electronic ISSN: 1660-4601
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Published by MDPI Publishing
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    ISSN: 0368-2048
    Keywords: Furanone ; Ionization potential ; Isomer ; Lactone ; UPS
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 5
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    ISSN: 0368-2048
    Keywords: Furanone ; Isomer ; Kinetics ; Lactone ; UPS
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Materials research innovations 2 (1998), S. 150-163 
    ISSN: 1433-075X
    Keywords: Key words Friction stir welding ; Dynamic recrystallization ; Dissimilar metal joining ; Intercalation microstructures ; Extreme plastic flow
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  Dissimilar plates (0.6 cm thick) of copper and 6061 aluminum alloy; and 2024 aluminum alloy and 6061 aluminum alloy were friction-stir welded at various rotation speeds (400–1200 rpm) and traverse speeds of 1 to 3 mm/s, and produced variations of vortex and other swirl-like intercalations, especially near the weld-zone/work-piece interface. These vortex-like structures are composed of dynamically recrystallized, fine-grained intercalation microstructures which have been observed by optical metallography, scanning electron microscopy and transmission electron microscopy. They are similar to those characterizing mechanical alloying. Such microstructures are especially fascinating because although they resemble vortex instabilities which occur in turbulent fluids, they are formed by extreme deformation in the solid state since centerline temperatures through the weld zone are about 420°C, or ∼0.7 TM in the 6061 aluminum system.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Pure and applied geophysics 145 (1995), S. 123-137 
    ISSN: 1420-9136
    Keywords: Porous media ; coupling theory ; Xinfengjiang reservoir ; induced earthquakes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract Theory of the coupling of stress-pore pressure in the saturated, elastic porous media is used in the study of the formation mechanism of the Xinfengjiang reservoir-induced earthquakes. Based on the results, it is believed that compared with the mechanism of additional stress in the vicinity of the reservoir, the mechanism of the coupling of additional stress and pore pressure may be more well-founded for the occurrence of reservoir-induced earthquakes.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Both tetrodotoxin-sensitive (TTX-S) and TTX-resistant (TTX-R) voltage-dependent Na+ channels are expressed in the human neuroblastoma cell line NB-1, but a gene encoding the TTX-R Na+ channel has not been identified. In this study, we have cloned cDNA encoding the α subunit of the TTX-R Na+ channel in NB-1 cells and designated it hNbR1. The longest open reading frame of hNbR1 (accession no. 〈accessionId ref="info:ddbj-embl-genbank/AB158469"〉AB158469) encodes 2016 amino acid residues. Sequence analysis has indicated that hNbR1 is highly homologous with human cardiac Nav1.5/SCN5A with 〉 99% amino acid identity. The presence of a cysteine residue (Cys373) in the pore-loop region of domain I is consistent with the supposition that hNbR1 is resistant to TTX. Analysis of the genomic sequence of SCN5A revealed a new exon encoding S3 and S4 of domain I (exon 6A). In addition, an alternative splicing variant, lacking exon 18, that encodes 54 amino acids in the intracellular loop between domains II and III was found (hNbR1-2; accession no. 〈accessionId ref="info:ddbj-embl-genbank/AB158470"〉AB158470). Na+ currents in human embryonic kidney cells (〈accessionId ref="info:ddbj-embl-genbank/HEK293"〉HEK293) transfected with hNbR1 or hNbR1-2 showed electrophysiological properties similar to those for TTX-R INa in NB-1 cells. The IC50 for the TTX block was ≈ 8 µm in both variants. These results suggest that SCN5A has a newly identified exon for alternative splicing and is more widely expressed than previously thought.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 345-346 (Aug. 2007), p. 1067-1070 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Microstructure, hardness and mechanical properties of the 1Cr5Mo steel tubes for thecoking furnace at super temperature were investigated in this paper. It revealed that undersuper-temperature, oxidation corrosion for the furnace tubes was strengthened, wall thickness wasevident thinner, pearlite in microstructure was spheroidised mostly, strength would be decreasedand marked degradation in material occurred
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 10
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 400-402 (Oct. 2008), p. 483-488 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Based on the improved equation of concrete heat-generation rate and an improved calculation method of temperature stress, the temperature effect of concrete hydration heat is simulated successfully in ANSYS. Comparison between the numerical simulation results and test results of a scaled model of blast furnace foundation indicates that the calculated temperature field based on the improved equation and method is much closer to that of test than which obtained by the old equation and method. By using the stress superposition principle, the temperature-stress field can be calculated with considering the change of material behavior with temperature and time
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...