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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 117 (1953), S. 70-72 
    ISSN: 1432-0568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Development genes and evolution 158 (1967), S. 147-163 
    ISSN: 1432-041X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Development genes and evolution 155 (1964), S. 162-180 
    ISSN: 1432-041X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary 1. The unilateral or bilateral extirpation of the ectoderm of the P.H.M. region in stages 5 to 8 in the chicken embryo exerts no influence in heart determination and differentiation, since in all the cases a morphological and structurally typical heart is formed. 2. Neither does the extirpation of the ectoderm interfere in the migratory process of the cells of the P.H.M., since, with the exception of one case of cardia bifida, a unique heart is formed in a unique pericardial cavity. 3. The extirpation of the ectoderm exerts a clear influence over the situation of the heart and over its curvatures since when the ablation of the ectoderm is unilateral, the heart is displaced toward the side opposite that of the extirpation. It is, therefore, normal in the extirpations of the left ectoderm and inverted in those of the right. 4. The primary fore-gut pocket does not form on the side where the ectoderm has been extirpated. This, therefore, exerts a clear influence on the formation of the fore-gut pockets and in the form the fore-gut takes. 5. The extirpation of the ectoderm in stages 6 and 7 constantly inhibits the process of the closing of the neural canal in the encephalic region (mesencephalon and anterior part of the rhombencephalon), the neural differentiation normally continuing its process. This suggests that the force of the neural folds during the formation of the neural tube is transmitted to them through the ectoderm.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Development genes and evolution 160 (1968), S. 298-312 
    ISSN: 1432-041X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Grafting regions of the blastodisc of the chick, labeled with H3-thymidine at Stages 5 and 6 ofHamilton andHamburger, is a very useful technique for following the morphogenetic movements of the grafted material. Areas (E-M) of the blastodisc of 2.75 by 0.55 mm, grafted in the homologous region of an embryo, participate in its morphogenetic movements. The labeled reversed cardiac area can sometimes be incorporated into the host, and a tubular heart can develop which includes some of the graft tissue, Figs. 3, 4, 5, and 6. The morphogenetic movements shaping the anterior intesinal portal and early foregut can occur despite the reversal of a large rectangle of the endomesoderm, Fig. 6. The coelomic epithelium lining the operated side, a part of the myoepicardium of this side, as well as the endoderm of the ventral portion of the foregut, and, more caudally, half of the anterior intestinal portal are derived from the graft as shown by strong radioactive labeling of the cells, Figs. 3, 4 and 6. The morphogenetic movements of the graft endoderm and mesoderm are independent, the pre-heart mesoderm moving in a cranial direction, while the endoderm extends caudally, Figs. 3 and 4. This study raises an interesting question: Can the original cephalic preconal cardiogenic mesoderm regulate to form sinoatrial tissue (and vice versa) ? The evidence obtained in the present investigation is not extensive enough to warrant conclusions as to the important question of “regulation”; for this a considerable number of operated embryos is required in which a recognizable normal heart has developed (up to Stage 12–13).
    Type of Medium: Electronic Resource
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