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  • 1
    Online Resource
    Online Resource
    Wiesbaden : Teubner
    Keywords: Finanzmathematik ; Aufgabensammlung ; Finanzmathematik
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (221 S.) , graph. Darst.
    Edition: 1. Aufl.
    ISBN: 9783835100862 , 9783835190993
    Series Statement: Teubner Studienbücher Wirtschaftsmathematik
    RVK:
    Language: German
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 296 (1999), S. 371-383 
    ISSN: 1432-0878
    Keywords: Key words Oviduct epithelium ; Perfusion culture ; Cell support ; Permeable membranes ; Reverse transcription-polymerase chain reaction ; Bovine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract  The oviduct is the physiological site for key events in reproduction, such as capacitation of spermatozoa, fertilization and early embryonic development. Interactions between oviduct epithelial cells and gametes or embryos cannot sufficiently be studied in vivo. Therefore, model systems are needed which mimic in vivo conditions most closely. In this study we optimised the method for isolating bovine oviduct cells and compared different cell support materials as well as two culture systems (perfusion vs static culture) for their ability to maintain characteristic morphological and functional features of oviduct cells. Out of nine different cell support materials tested, cellulose nitrate (0.45 µm pore size) was the most suitable to maintain cells in a manner similar to freshly isolated oviduct epithelial cells. Comparing static vs perfusion culture by electron microscopy, morphological differences of the cells were insignificant in the first days of culture, while they became more evident after 8 days. The cells in the static system lost typical characteristics such as columnar shape, cilia and secretory protrusions, while these features were still present in perfusion culture. In addition, intense ciliogenesis and cytoplasmic organelles for protein synthesis were found under perfusion conditions. These findings were underlined by differences in expression of the oviduct-specific oestrus-associated glycoprotein 85–97 kDa (GP 85–97) gene as revealed by semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR). The RNA levels of this specific gene were significantly higher in perfusion compared to the static culture system. Our data show clear advantages of perfusion vs static culture for primary bovine oviduct epithelial cells.
    Type of Medium: Electronic Resource
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  • 3
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    Kiel: Kiel Institute for the World Economy (IfW)
    Publication Date: 2013-08-16
    Keywords: ddc:330
    Language: English
    Type: doc-type:conferenceObject
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  • 4
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1987 (1987), S. 1095-1099 
    ISSN: 0170-2041
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Ansa-Seco SteroidsDiels-Alder adducts of monosubstituted acetylene compounds to ergosterol acetate (6) in a retro reaction give rise to aromatic ansa compounds of type 8a. The regioselectivity of the propargylic aldehyde addition is proven by an X-ray structure determination of dimethyl acetal 8b. Structures of other cycloaddition products are correlated to this aldehyde by chemical transformations.
    Notes: Durch Retro-Dien-Reaktion einiger Diels-Alder-Addukte des Ergosterolacetats (6) mit monosubstituierten Acetylenverbindungen werden aromatische Ansa-Verbindungen vom Typ 8a gewonnen. Die Regioselektivität der Addition von Propargylaldehyd folgt aus der Röntgenstrukturanalyse des kristallinen Dimethylacetals 8b. Andere Addukte können chemisch mit diesem Produkt korreliert werden.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 5
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    Kiel: Kiel Institute for the World Economy (IfW)
    Publication Date: 2016-07-20
    Description: We consider a portfolio optimization problem in a Black-Scholes model with n stocks, in which an investor faces both fixed and proportional transaction costs. The performance of an investment strategy is measured by the average return of the corresponding portfolio over an infinite time horizon. At first, we derive a representation of the portfolio value process, which only depends on the relative fractions of the total portfolio value that the investor holds in the different stocks. This representation allows us to consider these so-called risky fractions as the decision variables of the investor. We show a certain kind of stationarity (Harris recurrence) for a quite flexible class of strategies (constant boundary strategies). Then, using renewal theoretic methods, we are able to describe the asymptotic return by the behaviour of the risky fractions in a typical period between two trades. Our results generalize those of [4], who considered a financial market model with one bond and one stock, to a market with a finite number n〉1 of stocks.
    Keywords: G11 ; C61 ; ddc:330 ; Portfolio theory ; transaction costs ; Harris recurrence ; renewal theory ; Portfolio-Management ; Strategie ; Transaktionskosten ; Black-Scholes-Modell ; Theorie
    Language: English
    Type: doc-type:workingPaper
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  • 6
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    Kiel: Kiel Institute for the World Economy (IfW)
    Publication Date: 2016-07-20
    Description: Guasoni (2006) introduced a simple condition for the absence of arbitrage opportunities. In this note we show that his results remain valid under a weaker notion of arbitrage which arises by excluding liquidation costs from the value process of a portfolio.
    Keywords: G10 ; G12 ; C60 ; ddc:330 ; Arbitrage ; transaction costs ; fractional Brownian motion ; Wertpapierhandel ; Arbitragegeschäft ; Transaktionskosten ; Markovscher Prozess ; Theorie
    Language: English
    Type: doc-type:workingPaper
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  • 7
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 439 (2006), S. 973-977 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant neuromuscular disorder that is not due to a classical mutation within a protein-coding gene. Instead, almost all FSHD patients carry deletions of an integral number of tandem 3.3-kilobase repeat units, termed D4Z4, located ...
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 85 (1992), S. 88-92 
    ISSN: 1432-0533
    Keywords: Immunohistochemistry ; Vimentin ; Desmin ; Muscle ; Regeneration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Localization and distribution of desmin and vimentin have been studied in different neuromuscular disorders using monoclonal antibodies. We have demonstrated that vimentin, although virtually absent in normal human muscle fibers, is expressed in regenerating fibers in different neuromuscular disorders. Moreover, these fibers showed a strong positivity with desmin antibodies. In normal muscle fibers desmin is only localized at Z-line level. These results suggest that desmin and vimentin may be over-expressed during muscle regeneration processes, probably because of their importance in the structural organization of the sarcomere.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 87 (1994), S. 371-376 
    ISSN: 1432-0533
    Keywords: Key words: Mitochondrial myopathy – Ragged red fibers – In situ hybridization – Immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. In situ hybridization combined with immunohistochemical techniques has been applied to study patients affected by mitochondrial myopathies with large mitochondrial (mt)DNA deletions. All patients' muscle biopsies showed ragged red fibers (RRFs) and cytochrome oxidase (COX) deficiency. Two digoxygenin-labeled, polymerase chain reaction (PCR)-amplified DNAs were used as probes. One probe was designed to hybridize only with wild-type mtDNAs, while the other recognized both wild-type and deleted mtDNAs. Concomitant immunocytochemical analysis using antibodies against subunits II, III (encoded by mtDNA), and IV (encoded by nuclear DNA) of COX was carried out. In our patients deleted mtDNAs are overexpressed in COX-negative RRFs, while wild-type mtDNAs are decreased in the same fibers. Immunohistochemistry studies show that COX IV is overexpressed in RRFs and that COX II and COX III subunits are still present. Deleted mtDNAs are spatially segregated in muscle fibers, where they interfere with the local population of normal mitochondrial genomes, causing a regional deficiency of the mitochondrial respiratory activity.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 96 (1998), S. 509-514 
    ISSN: 1432-0533
    Keywords: Key words Limb-girdle dystrophy ; Sarcoglycan ; complex ; Sarcoglycanopathy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Autosomal recessive limb-girdle muscular dystrophies are a heterogeneous group of genetic diseases with a wide spectrum of clinical severity and age of onset; mutations in the gene encoding the dystrophin-associated sarcoglycan proteins (α, β, γ and δ) have recently been shown to cause some cases of these myopathies (primary sarcoglycanopathies, types 2D, 2E, 2C and 2F, respectively). In this study we have examined a large population of Italian myopathic patients to determine the frequency of α-, β- and γ-sarcoglycan deficiency and to correlate molecular defects with clinical phenotypes; to exclude the presence of primary dystrophinopathies both genetic and immunological analysis of dystrophin was performed. We report 12 patients (10 male and 2 female) with deficiency of either one or more sarcoglycan proteins. They were aged 8–56 years with onset between 4 and 30 years of age; they all presented with either mild, moderate or severe limb-girdle involvement associated with elevated blood creatine kinase levels and myopathic pattern at EMG; one was also affected with a mild dilation cardiomyopathy. All patients, except one, showed pathological muscle histological changes. Absence of all three proteins always correlates with severe forms, whereas mild protein deficiencies or isolated partial α-sarcoglycan deficiency correlate with either severe, moderate or mild forms.
    Type of Medium: Electronic Resource
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