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  • 1
    Online Resource
    Online Resource
    Wiesbaden : Springer Fachmedien Wiesbaden
    Keywords: Werkstoff ; Mechanische Eigenschaft ; Lehrbuch ; Werkstoff ; Mechanische Eigenschaft
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (XV, 545 Seiten 331 Abb., 33 Abb. in Farbe)
    Edition: 5., korr. Aufl. 2016
    ISBN: 9783658137953 , 9783658137946
    DDC: 621
    RVK:
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    Language: German
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  • 2
    Online Resource
    Online Resource
    Stuttgart [u.a.] : Teubner
    Keywords: Werkstoff ; Mechanische Eigenschaft ; Lehrbuch ; Werkstoff ; Mechanische Eigenschaft
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource
    Edition: 2., durchges. und erw. Aufl.
    ISBN: 3835100084 , 9783835100084 , 9783835190412
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    Language: German
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  • 3
    Online Resource
    Online Resource
    Wiesbaden : Springer Vieweg
    Keywords: Werkstoff ; Mechanische Eigenschaft ; Mechanical engineering ; Mechanics ; Mechanics, Applied ; Mechanical Engineering ; Solid Mechanics ; Lehrbuch ; Werkstoff ; Mechanische Eigenschaft
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (XIII, 549 Seiten) , Illustrationen, Diagramme (teilweise farbig)
    Edition: 6., aktualisierte Auflage
    ISBN: 9783658268022
    Series Statement: Lehrbuch
    DDC: 621
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    Language: German
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  • 4
    Book
    Book
    Stuttgart [u.a.] : Teubner
    Keywords: Werkstoff ; Mechanische Eigenschaft ; Lehrbuch ; Werkstoff ; Mechanische Eigenschaft
    Type of Medium: Book
    Pages: XIII, 521 S. , Ill., graph. Darst.
    Edition: 2., durchges. und erw. Aufl.
    ISBN: 3835100084 , 9783835100084
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    Language: German
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  • 5
    Online Resource
    Online Resource
    Wiesbaden : Springer Fachmedien Wiesbaden
    Keywords: Werkstoff ; Mechanische Eigenschaft ; Lehrbuch ; Werkstoff ; Mechanische Eigenschaft
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource , I
    Edition: 4., überarb. u. erw. Aufl.
    ISBN: 9783834822413
    Series Statement: Studium
    DDC: 620.11292
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    Language: German
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  • 6
    Online Resource
    Online Resource
    Wiesbaden : Vieweg + Teubner
    Keywords: Werkstoff ; Mechanische Eigenschaft ; Lehrbuch ; Werkstoff ; Mechanische Eigenschaft
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource
    Edition: 3., durchges. und korr. Aufl.
    ISBN: 9783835102408 , 9783835192454
    Series Statement: Studium
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    Language: German
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Monatsschrift Kinderheilkunde 145 (1997), S. 810-814 
    ISSN: 1433-0474
    Keywords: Schlüsselwörter Septische Granulomatose ; p47phox-Mangel ; Pseudogen ; Allergische Alveolitis ; Aspergillus ; Key words Autosomal CGD ; p47phox deficiency ; Pseudogene ; Hypersensitivity ; Pneumonitis ; Aspergillus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Chronic granulomatous disease (CGD) is caused by the inability of phagocytes to kill ingested germs by microbicidal reactive oxygen. Especially forms of CGD with retained ability to produce some reactive oxygen sometimes tend to imitate other diseases. An 8-year-old girl with a normal history presented with many symptoms matching those of hypersensitivity pneumonitis like restrictive ventilation disorder, suggestive chest x-ray, a majority of CD8 positive lymphocytes in the broncho-alveolar-lavage fluid (BAL), suggestive histological valuation. Hints for the true underlying disease like neutrophilia and a high anti-Aspergillus-titer could be overlooked easily. The patient was treated with steroids and antibiotics because an infection could not be excluded. The CGD had not been recognised at this time, however. After a significant improvement for a short time the patient experienced a dramatic respiratory deterioration. A lot of Aspergillus could now be found in the BAL. Finally the patient died because of an ARDS and respiratory insufficiency even though signs of the Aspergillus infection improved significantly. Discussion: Whenever CGD must be considered appropriate diagnostics have to be performed– especially before treatment with steroids.
    Notes: Zusammenfassung Die Septische Granulomatose wird durch die Unfähigkeit von Phagozyten hervorgerufen, aufgenommene Erreger mit Hilfe von mikrobizidem reaktivem Sauerstoff abzutöten. Besonders Formen der Septischen Granulomatose mit Restaktivität neigen dazu, andere Krankheitsbilder manchmal täuschend ähnlich nachzuahmen und den Behandler in eine diagnostische Falle zu locken. Eine klinisch bisher unauffällige 8jährige Patientin zeigte viele Symptome, die sehr gut mit einer exogen allergischen Alveolitis vereinbar waren, wie u.a. eine ausgeprägte restriktive Ventilationsstörung, ein suggestives Röntgenbild des Thorax, in der Mehrzahl CD8-positive Lymphozyten in der bronchoalveolären Lavageflüssigkeit sowie eine suggestive histologische Befundung. Hinweise auf die wahre Grunderkrankung, wie Neutrophilie und hoher Anti-Aspergillustiter konnten leicht übersehen werden. Da auch eine infektiöse Genese nicht auszuschließen war, wurde die Patientin in Unkenntnis der Grunderkrankung mit einer Kombination aus Antibiotika und Prednisolon behandelt. Nach kurzzeitiger deutlicher Besserung kam es zu einer dramatischen respiratorischen Verschlechterung mit massivem nun im Tracheobronchialsekret nachweisbaren Aspergillusbefall. Die Patientin verstarb unter dem Bild eines ARDS in der respiratorischen Insuffizienz trotz erfolgreich zurückgedrängter Aspergillusinfektion. Diskussion: In allen Fällen, bei denen die Septische Granulomatose zur Differentialdiagnose gehört, muß– insbesondere vor einer Steroidtherapie – eine adäquate Diagnostik erfolgen.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 426-432 (Aug. 2003), p. 2527-2532 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 157 (1993), S. 637-643 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Flow cytometric analyses were performed to study intracellular single-cell calcium transients ([Ca2+]i) in suspended human neutrophils during the initial phase of N-formyl peptide stimulation. Thereby, two neutrophil populations became apparent. Early maximally Ca2+-responding (high fluorescence) neutrophils and not-yet Ca2+-responding (low fluorescence) neutrophils, but no neutrophils with intermediate levels of [Ca2+]i, were detected. Within 7 s the number of low fluorescence neutrophils decreased and the number of high fluorescence neutrophils increased maximally. This suggests that [Ca2+]i transients occurred abruptly in individual neutrophils within a time interval below 1 s. At lower N-formyl peptide concentrations the lag times of individual neutrophils and the interval time of maximal activation of the [Ca2+]i-responding neutrophil population increased, however the percentage of [Ca2+]i-responding cells decreased. Surprisingly, no influence of the N-formyl peptide concentration on the [Ca2+]i-induced fluorescence signal of the individual cell was observed: it was always in an almost maximal range or not responding. In parallel, binding studies performed with fluorescein-labeled N-formyl peptide revealed that the heterogeneity of [Ca2+]i-responding cells cannot be explained by different receptor occupancy. In summary, this study demonstrates that [Ca2+]i transients induced by N-formyl peptides in suspended individual human neutrophils occur very rapidly in an almost “all-or-none manner” and that the mean increasing fluorescence signal of a calcium indicator within a whole neutrophil population results from varying lag times of the individual cells, rather than from the mean simultaneous progress of many cells. © 1993 Wiley-Liss, Inc.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 426-432 (Aug. 2003), p. 755-760 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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