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  • 1
    Online Resource
    Online Resource
    Rijeka, Croatia : InTech
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (172 Seiten) , Illustrationen, Diagramme
    ISBN: 9789535136149
    URL: Volltext  (kostenfrei)
    URL: Volltext  (kostenfrei)
    Language: English
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  • 2
    Online Resource
    Online Resource
    Rijeka, Croatia : InTech
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource
    ISBN: 9789535131786
    URL: Volltext  (kostenfrei)
    URL: Volltext  (kostenfrei)
    Language: English
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  • 3
    Online Resource
    Online Resource
    London : IntechOpen
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource , Illustrationen, Diagramme
    ISBN: 9781789854442
    URL: Volltext  (kostenfrei)
    URL: Volltext  (kostenfrei)
    Language: English
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  • 4
    Online Resource
    Online Resource
    Rijeka, Croatia : InTech
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource , Illustrationen, Diagramme
    ISBN: 9789535129547
    URL: Volltext  (kostenfrei)
    URL: Volltext  (kostenfrei)
    Language: English
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  • 5
    Online Resource
    Online Resource
    London : IntechOpen
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource , Illustrationen
    ISBN: 9781789236415
    URL: Volltext  (kostenfrei)
    URL: Volltext  (kostenfrei)
    Language: English
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  • 6
    Online Resource
    Online Resource
    London : IntechOpen
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource , Illustrationen
    ISBN: 9781789230918
    URL: Volltext  (kostenfrei)
    URL: Volltext  (kostenfrei)
    Language: English
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Helicobacter 10 (2005), S. 0 
    ISSN: 1523-5378
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background.  Distinct human leukocyte antigen (HLA)-DQ genes have been associated with an increased or reduced risk for gastric cancer, but its association with Helicobacter pylori status is controversial. In the present study we evaluated the influence of host HLA DQA1 and DQB1 loci, H. pylori genotype, and socio-economic factors on predicting H. pylori-associated distal gastric cancer in a southern European population.Material and methods.  In a prospective case–control (1 : 2) study, 42 patients with H. pylori-associated distal gastric cancer were matched by age (±5 years) and gender to 84 patients with H. pylori-associated benign gastroduodenal disease (controls). The level of education received, smoking status, alcohol consumption, origin and familial history of gastric cancer were registered at inclusion. HLA DQA1 and DQB1 typing and H. pylori genotyping were determined from endoscopic gastric mucosal biopsies.Results.  Compared with control patients, a positive association with cagA+ strains (p 〈 .002) and a negative association with vacA-s2 strains (p 〈 .02) was found in patients with distal gastric cancer. At the DQB1 locus, the *0602 allele was more frequent in distal gastric cancer than in controls (26.2% vs. 4.8%; p 〈 .005). After correction for multiple comparisons (exact multiple regression analysis) the cagA+ status and the DQB1*0602 allele were associated with an increased distal gastric cancer risk (OR 3.7; 95% CI = 1.33–12.26 and OR 4.82; 95% CI = 1.24–19.83, respectively) whereas the vacA-s2 status was associated with a decreased risk (OR 0.33; 95% CI = 0.10–0.94).Conclusion.  Our findings suggest that in the H. pylori-infected southern European population, the cagA genotype and the HLA-DQB1*0602 gene confer an increased risk for distal gastric cancer.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Digestive diseases and sciences 43 (1998), S. 1964-1969 
    ISSN: 1573-2568
    Keywords: OMEPRAZOLE ; DUODENAL ULCER ; MAINTENANCE TREATMENT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In most patients duodenal ulcer is a chronicrelapsing disease. If no active maintenance treatment oreradication therapy is given after healing, around70-100% of patients have a relapse during the first year. We conducted a double-blind multicenterstudy in 472 patients with duodenal ulcer. They weretreated with omeprazole 20 mg every morning for four oreight weeks and when healed were randomly allocated to maintenance treatment with either omeprazole20 mg every morning or ranitidine 150 mg at bedtime forup to six months. The patients were assessed byendoscopy at monthly intervals until healing occurred. Thereafter scheduled endoscopy was carried outafter 1, 3, and 6 months of maintenance treatment orimmediately in the event of a suspected relapse. Healingstatus (intention to treat approach) was 87% at four weeks and 93% at eight weeks. At sixmonths the estimated remission rate was 90% foromeprazole and 82% for ranitidine (P = 0.03, 95% CI1-15%). The incidence of adverse events was similarduring the two maintenance treatments. Treatment withomeprazole 20 mg every morning maintained significantlymore patients in remission than treatment withranitidine 150 mg at bedtime.
    Type of Medium: Electronic Resource
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  • 9
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    Brasília: Instituto de Pesquisa Econômica Aplicada (IPEA)
    Publication Date: 2018-04-18
    Description: The Índice de Vulnerabilidade Social (IVS) and the Atlas da Vulnerabilidade Social (AVS) of the municipalities and metropolitan regions arise by an effort of selection, development and georeferencing of indicators that could express conditions of social vulnerability in the different scales of brazilian territory. Such conditions may emerge from plural factors that are part of the social issue, like the contexts of income and labour, education and health, mobility, habitation and sanitation. The IVS is a sinthetic index constructed with indicators that express fragilities of this social factors. The text below presentes the process of criation of the IVS from your conceptual, methodological and statiscal aspects and limitations. After this presentation, the work will show na analysis of some IVS results, as well as your dimensions and indicatores for the years of 2000 e 2010, in order to delineate the conditions of social vulnerability in the brazilian territory and exemplify ways of data analysis available in the AVS.
    Keywords: O15 ; O18 ; R23 ; J15 ; ddc:330 ; social vulnerability ; sinthetic index ; Brazil ; public policy ; regional development
    Language: Portuguese
    Type: doc-type:workingPaper
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