Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination
Nature Publishing Group
Nature Archives 1869 - 2009
[Auszug] Novel approaches for the generation of more effective vaccines for HIV-1 are of significant importance. In this report we analyze the immunogenicity and efficacy of an HIV-1 DNA vaccine encoding env, rev and gag/pol in a chimpanzee model system. The immunized animals developed specific cellular and ...
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