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  • 1
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 78 (2001), S. 3621-3623 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Ultrathin Pb films supported by Al film were made by using cold-rolling and ion-beam thinning techniques. The morphological instability of the Pb film under electron-beam irradiation was investigated by means of in situ transmission electron microscopy observations. It has been found that under electron-beam irradiation, Pb films with an incoherent Pb/Al interface spheroidized into Pb particles, but those with a semicoherent Pb/Al interface were stable in morphology. The morphological stability of thin films depends on the microstructure and the thermodynamic property of the interphase boundary. A critical interfacial energy for the spheroidization of thin films was determined based on a thermodynamics analysis. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Haemophilia 10 (2004), S. 0 
    ISSN: 1365-2516
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary.  We reported a 51-year-old man who developed a severe haematuria with a prolonged prothrombin time (PT) and activated partial thromboplastin time (aPTT). Laboratory evaluation revealed the presence of specific factor V inhibitors. No underlying diseases and associated conditions have been identified. The patient improved after immunosuppressive therapy. However, the FV level remained low, indicating incomplete inhibitor eradication. The clinical course of our patient was consistent with the observations by others that FV inhibitor can be persistent for months or years.
    Type of Medium: Electronic Resource
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  • 3
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    BMJ Publishing
    In: BMJ Open
    Publication Date: 2014-07-02
    Description: Objective To explore the attitudes and perceptions of patient safety culture for pharmacy workers in China by using a Pharmacy Survey on Patient Safety Culture (PSOPSC), and to assess the psychometric properties of the translated Chinese language version of the PSOPSC. Design Cross-sectional study. Participants Data were obtained from 20 hospital pharmacies in the southwest part of China. Methods We performed 2 test to explore the differences on pharmacy staff in different hospital and qualification levels and countries towards patient safety culture. We also computed descriptive statistics, internal consistency coefficients and intersubscale correlation analysis, and then conducted an exploratory factor analysis. A test–retest was performed to assess reproducibility of the items. Results A total of 630 questionnaires were distributed of which 527 were responded to validly (response rate 84%). The positive response rate for each item ranged from 37% to 90%. The positive response rate on three dimensions (‘Teamwork’, ‘Staff Training and Skills’ and ‘Staffing, Work Pressure and Pace’) was higher than that of Agency for Healthcare Research and Quality (AHRQ) data (p〈0.05). There was a statistical difference in the perception of patient safety culture at different hospital and qualification levels. The internal consistency of the total survey was comparatively satisfied (Cronbach's α=0.89). Conclusions The results demonstrated that among the pharmacy staffs surveyed in China, there was a positive attitude towards patient safety culture in their organisations. Identifying perspectives of patient safety culture from pharmacists in different hospital and qualification levels are important, since this can help support decisions about action to improve safety culture in pharmacy settings. The Chinese translation of the PSOPSC questionnaire (V.2012) applied in our study is acceptable.
    Keywords: Open access, Global health, Health services research
    Electronic ISSN: 2044-6055
    Topics: Medicine
    Published by BMJ Publishing
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  • 4
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    Genetics Society of America (GSA)
    Publication Date: 2014-10-17
    Description: Meiotic nonreduction resulting in unreduced gametes is thought to be the predominant mechanism underlying allopolyploid formation in plants. Until now, however, its genetic base was largely unknown. The allohexaploid crop common wheat ( Triticum aestivum L.), which originated from hybrids of T. turgidum L. with Aegilops tauschii Cosson, provides a model to address this issue. Our observations of meiosis in pollen mother cells from T. turgidum x Ae. tauschii hybrids indicated that first division restitution, which exhibited prolonged cell division during meiosis I, was responsible for unreduced gamete formation. A major quantitative trait locus (QTL) for this trait, named QTug.sau-3B , was detected on chromosome 3B in two T. turgidum x Ae. tauschii haploid populations. This QTL is situated between markers Xgwm285 and Xcfp1012 and covered a genetic distance of 1 cM in one population. QTug.sau-3B is a haploid-dependent QTL because it was not detected in doubled haploid populations. Comparative genome analysis indicated that this QTL was close to Ttam-3B , a collinear homolog of tam in wheat. Although the relationship between QTug.sau-3B and Ttam requires further study, high frequencies of unreduced gametes may be related to reduced expression of Ttam in wheat.
    Electronic ISSN: 2160-1836
    Topics: Biology
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  • 5
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    BMJ Publishing
    In: BMJ Open
    Publication Date: 2017-09-05
    Description: Objective Published research has not considered acute diseases and injuries in assessing the impact of varying disease counts on health-related quality of life (HRQoL). We used Chinese value sets of EQ-5D-3L to examine the relationship between the number of diseases individuals had (including chronic diseases, acute diseases and injuries) and their HRQoL. Methods A total of 19 387 individuals aged 18 years and older were included in the study. Using data from the First Provincial Health Services Survey of Hunan, China, HRQoL was assessed with the EQ-5D-3L scale, a standardized instrument developed by the EuroQoL group. The EQ-5D-3L utility score was calculated using the Chinese EQ-5D-3L value set. This survey coded disease using the list of 133 conditions that was defined by the First Provincial Health Services Survey of Hunan, China, based on the 10th International Classification of Diseases. 126 conditions were disease-related and were therefore included in data analysis. Results Of 15 245 respondents, urban residents and male constituted 53.0% and 48.2%, respectively. 19.3% of respondents had one disease and 5.0% had at least two diseases. Of the five dimensions of the EQ-5D-3L, the pain/discomfort dimension had the highest proportion of moderate or serious problems among the respondents (14.4%, 95% CI 10.5% to 18.2%). The average Visual Analogue Scale (VAS) score and utility score were 78.0 (95% CI 76.9 to 79.1) and 0.958 (95% CI 0.946 to 0.970), respectively. Residents with 1 and ≥2 diseases had higher proportions of moderate or serious problems in five dimensions of the EQ-5D-3L scale during the previous 2 weeks than those without disease after controlling for location (urban/rural), sex, age, education level and household income, respectively (adjusted ORs: 3.1–3.7 and 4.4–6.6, respectively). The mean of the EQ VAS score was 8.4 and 13.6 points lower in respondents with 1 and ≥2 diseases than in respondents without disease; the corresponding mean score difference was 0.048 and 0.086 in EQ-5D-3L utility score. Disease-specific analyses were not conducted due to the inadequacy of sample size. Conclusions The HRQoL of residents aged 18 years and older declines distinctly as the number of diseases increases. Actions should be taken to improve the HRQoL of residents with multiple diseases in China (including acute diseases, chronic diseases and injuries).
    Keywords: Open access, Health services research
    Electronic ISSN: 2044-6055
    Topics: Medicine
    Published by BMJ Publishing
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  • 6
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    Oxford University Press
    Publication Date: 2017-01-05
    Description: Increasing evidence has revealed that RNA subcellular localization is a very important feature for deeply understanding RNA's biological functions after being transported into intra- or extra-cellular regions. RNALocate is a web-accessible database that aims to provide a high-quality RNA subcellular localization resource and facilitate future researches on RNA function or structure. The current version of RNALocate documents more than 37 700 manually curated RNA subcellular localization entries with experimental evidence, involving more than 21 800 RNAs with 42 subcellular localizations in 65 species, mainly including Homo sapiens, Mus musculus and Saccharomyces cerevisiae etc. Besides, RNA homology, sequence and interaction data have also been integrated into RNALocate. Users can access these data through online search, browse, blast and visualization tools. In conclusion, RNALocate will be of help in elucidating the entirety of RNA subcellular localization, and developing new prediction methods. The database is available at http://www.rna-society.org/rnalocate/ .
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Wood science and technology 31 (1997), S. 265-277 
    ISSN: 0043-7719
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Summary  Thick specimens of two softwoods were dried in a laboratory radio frequency/vacuum (RF/V) kiln in order to investigate the internal moisture flow patterns. The spatial moisture distributions in the longitudinal and transverse directions were monitored as a function of time in a number of runs. The results indicated that both longitudinal and transverse moisture transfer modes contribute on the overall moisture flow occurring within wood, but there was no distinction as to the percentage contribution of each to the overall flux. There were no abrupt drying front changes and no moisture discontinuities observed during drying. A second group of runs was also carried out using end-matched specimens to study its length effects on drying characteristics, such as drying rate, and internal vapor pressure and temperature profiles. The results demonstrated that short specimens dried faster than long ones at moisture contents above the fiber saturation point.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    ISSN: 1588-2780
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Inhalation of tobacco smoke is ranked second to food as a source of210Pb and210Po exposure to man. Assay of210Pb and210Po in commercially available tobacco collected from many countries have been carried out to assess the potential risk from210Po present in tobacco. The range of210Po contained in the tobacco grands varied from 10.08 to 15.0 mBq/tob or 13.0 to 20.1 mBq/g and the mean was 11.6 mBq/tob or 15.4 mBq/g. During the International Standard Smoking process about 50% of210Po present in tobaccos was transferred into the smoke and the other 50% remained in the ash and butt. About 10% of the total210Po of tobacco was inhaled by smoke through mainstream smoke. One pack-a-day smoker inhaled 24 mBq of210Po per day through smoking and the annual inhalation was 8.8 Bq. The risk of mortality from lung cancer caused by210Po in tobaccos was 18 per million persons for the above model.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Ionics 1 (1995), S. 59-62 
    ISSN: 1862-0760
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Magnesium sensitive probes were constructed and tested in different melts of commercial aluminium-magnesium alloys. The probes were composed of a porous magnesium oxide one closed end tube or thimble to which a magnesium conducting salt is impregnated. The activity of magnesium in the aluminium-magnesium melt was determined with report to a pure magnesium reference contained in the inside of the thimble and sealed from the surrounding atmosphere and melt by zirconia based cement. Measurements were conducted in various commercial aluminium-magnesium alloys under inert atmosphere as well as in air.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Chromatographia 42 (1996), S. 385-388 
    ISSN: 1612-1112
    Keywords: Capillary electrophoresis ; Diastereomeric isomers ; β-Cyclodextrin in the running buffer ; 1,3-Disubstituted tetrahydro-β-carboline
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary Capillary zone electrophoresis with β-cyclodextrin as electrolyte additive has been investigated for the separation of the diastereomers of a 1,3-disubstituted tetrahydro-β-carboline. The effects of pH, buffer concentration, β-cyclodextrin concentration and applied voltage on resolution were investigated. This study shows that optimizing the assay conditions leads to maximum chiral separation or resolution. The method enables further research on the quantitative analysis of these compounds.
    Type of Medium: Electronic Resource
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