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  • 2000-2004  (244)
  • 1945-1949  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of plant pathology 106 (2000), S. 135-146 
    ISSN: 1573-8469
    Keywords: Cicer arietinum ; quantitative epidemiology ; disease modelling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract Artificial inoculation experiments were carried out at 25°C to determine the effects of inoculum density of Fusarium oxysporum f.sp. ciceris races 0 (Foc-0) and 5 (Foc-5) and susceptibility of chickpea cultivars P-2245 and PV-61 on development of Fusarium wilt. Foc-5 proved much more virulent than Foc-0. Increasing the inoculum density of F. oxysporum f.sp. ciceris caused an exponential reduction in disease incubation period and a monomolecular increase of disease incidence and the area under the disease intensity progress curve. The extent of these effects was highest in the most conducive ‘P-2245’/Foc-5 combination and decreased in the less susceptible ‘PV-61’ and for the less virulent Foc-0, in that order. For ‘P-2245’/Foc-5, the highest disease intensity was attained with 6 chlamydospores g−1 of soil, the lowest inoculum density in the study. One thousand chlamydospores g−1 of soil of the same race were needed to attain a comparable disease intensity in ‘PV-61’. Twenty thousand chlamydospores g−1 of soil of Foc-0 were required for maximum disease intensity in ‘P-2245’. The disease intensity curves were adequately described by the Gompertz model. Using this model, a response surface for disease intensity was developed, in which the model parameters are expressed as a function of both time from inoculation and inoculum density. This response surface confirmed that the final amount of disease intensity increases in a monomolecular relationship with increasing inoculum density and showed that the relative rate of disease progress increases exponentially with increasing inoculum density of the pathogen.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Protoplasma 211 (2000), S. 198-206 
    ISSN: 1615-6102
    Keywords: Apoptosis ; Atherosclerosis ; Endothelium ; Lipoproteins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Endothelial lesion by oxidized low-density liproproteins (LDL) is one of the first stages in the development of atherosclerosis. The effect of these lipoproteins can range from a functional lesion of the endothelium to death of the endothelial cells by apoptosis. High-density lipoproteins (HDL) are one of the factors which can have a protective effect against the development of atheromatous plaques. The aim of this study is to establish whether the death of endothelial cells by apoptosis induced by oxidized LDLs is prevented by HDLs. ECV304 endothelial cells and bovine aorta endothelial cells were incubated with native LDLs, oxidized LDLs, and a combination of both oxidized LDLs and HDLs. Oxidized LDLs caused a significant increase of mortality mainly by apoptosis. However, when HDLs were added together with oxidized LDLs the percentage of total mortality, the degree of lipoprotein oxidation in the medium, and the percentage of cells in apoptosis were all significantly decreased. HDLs protect against the cytotoxicity of oxidized LDLs possibly by preventing the propagation of the oxidative chain in these lipoproteins.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 247 (2000), S. 461-462 
    ISSN: 1432-1459
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neural transmission 107 (2000), S. 177-181 
    ISSN: 1435-1463
    Keywords: Keywords: Parkinson's disease, oxidative stress, coenzyme Q10, mitochondrial function, serum levels.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary. We compared serum levels of coenzyme Q10 and the coenzyme Q10/cholesterol ratio in 33 patients with Parkinson's disease (PD) and 31 matched controls. The mean serum coenzyme Q10 levels did not differ significantly between the 2 study groups. Coenzyme Q10 levels were not correlated with age, age at onset, duration of the disease, scores of the Unified Parkinson Disease Rating Scale (UPDRS) or the Hoehn and Yahr staging in the PD group. The coenzyme Q10/cholesterol ratio had a significant correlation (although low) with duration of the disease (r = −0.46), total UPDRS score (r = −0.39), motor examination of the UPDRS (r = 0.45). These values were not influenced significantly by therapy with levodopa or dopamine agonists. The normality of serum coenzyme Q10 and coenzyme Q10/cholesterol ratio suggest that these values are not related with the risk for PD.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neural transmission 107 (2000), S. 233-239 
    ISSN: 1435-1463
    Keywords: Keywords: Dementia, Alzheimer's disease, vascular dementia, oxidative stress, coenzyme Q10, mitochondrial function, serum levels.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary. We compared serum levels of coenzyme Q10 and the coenzyme Q10/cholesterol ratio in 44 patients with Alzheimer's disease (AD), 17 patients with vascular dementia (VD), and 21 matched controls. The mean serum coenzyme Q10 and cholesterol levels and the coenzyme Q10/cholesterol ratio of patients with AD or VD did not differ significantly from those of controls. Coenzyme Q10 levels and coenzyme Q10/cholesterol ratio of AD or VD patients were not correlated with age, age at onset, duration of the disease or scores of the MiniMental State Examination. These results suggest that these values are not related with the risk for AD or VD.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neural transmission 107 (2000), S. 1021-1026 
    ISSN: 1435-1463
    Keywords: Keywords: Amyotrophic lateral sclerosis ; motoneuron disease ; coenzyme Q10 ; serum levels.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary. To elucidate whether serum coenzyme Q10 levels are related with the risk for amyotrophic lateral sclerosis (ALS), we compared serum levels of coenzyme Q10 and the coenzyme Q10/cholesterol ratio, in 30 patients with ALS and 42 matched controls using a high performance liquid chromatography technique. The mean serum coenzyme Q10 levels and the coenzyme Q10/cholesterol ratio did not differ significantly between the 2 study groups. These values were not influenced by the clinical form (spinal vs. bulbar) of ALS, and they did not correlate with age, age at onset, and duration of the disease. These results suggest that serum coenzyme Q10 concentrations are unrelated with the risk for ALS.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neural transmission 107 (2000), S. 445-449 
    ISSN: 1435-1463
    Keywords: Keywords: Parkinson's disease, insulin, cerebrospinal fluid levels.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary. We compared CSF levels insulin, measured by a Radioimmunoanalysis method, in 24 patients with Parkinson's disease (PD) and 21 matched controls. The CSF insulin levels did not differ significantly between PD patients and controls. CSF insulin levels were not correlated with age, age at onset, duration of the disease, scores of the Unified Parkinson Disease Rating Scale of the Hoehn and Yahr staging in the PD group. Antiparkinsonian therapy did not influence significantly and CSF levels of insulin. These results suggest that CSF insulin concentrations are not a biological marker of PD and its severity.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Plant pathology 51 (2002), S. 0 
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Fusarium oxysporum f. sp. ciceris (Foc), the causal agent of fusarium wilt of chickpea, consists of two pathotypes (yellowing and wilting) and eight races (races 0, 1B/C, 1A and 2–6) of diverse geographical distribution. Six Foc isolates, one each of races 0, 1B/C, 1A, 4, 5 and 6, representing the two pathotypes and the geographical range of the pathogen, showed identical sequences in introns of the genes for translation elongation factor 1α (EF1α), β-tubulin, histone 3, actin and calmodulin. Eleven additional Foc isolates representative of all races, pathotypes and geographical range, and three isolates of F. oxysporum (Fo) nonpathogenic to chickpea were further analysed for sequence variation in the EF1α gene. All isolates pathogenic to chickpeas shared an identical EF1α gene sequence, which differed from that shared by the three Fo isolates nonpathogenic to chickpea. EF1α gene sequences from the 17 Foc isolates and the three Fo isolates were compared with 24 EF1α gene sequences in GenBank from isolates of 11 formae speciales of F. oxysporum by parsimony analysis. Foc isolates formed a grouping distinct from other formae speciales and nonpathogenic isolates. These results indicate that F. oxysporum f. sp. ciceris is monophyletic.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    ISSN: 1473-4192
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Linguistics and Literary Studies
    Notes: The objective of the study is the analysis of private verbal thinking (PVT) during problem-solving activities carried out in a second language, as well as the study of the role that both the L1 and the L2 play in this process. PVT is defined as a particular type of private speech that surfaces during the reasoning process as a tool used in the resolution of problem-solving tasks. This study is based on the comparison of the PVT produced by three different groups of speakers: intermediate-level students of Spanish as an L2, advanced-level speakers of Spanish as an L2, and native speakers of Spanish. In addition to analyzing the general characteristics of this phenomenon, special attention is paid to the use that each of these groups made of their L1 in relation to their L2 during the resolution of a battery of logical, mathematical, and spatial questions. The ultimate goal of this study is to contribute to clarifying the importance of the L1 in an L2 language classroom, as it was found that the L1 manifested itself as a key factor in the process of reasoning.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Chromosome research 8 (2000), S. 277-283 
    ISSN: 1573-6849
    Keywords: inactive genes ; microspreads ; ribosomal cistrons ; SCs ; silent NORs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Giemsa-stained spread preparations and microspread preparations of Lemniscomys barbarus spermatocytes were made to investigate the meiotic behaviour of the peculiar sex chromosomes of this species. A typical sex vesicle is absent, as the X and Y chromosomes appear unfolded at zygotene and pachytene. In most cells, the sex chromosomes are associated at distal segments at metaphase I, probably as a consequence of a distal chiasma. The pairing segment is located in the heterochromatic regions of both sex chromosomes, which include silent ribosomal cistrons interspersed throughout the heterochromatin. This may suggest a possible involvement of ribosomal genes in both pairing and recombination processes. X–Y pairing proceeds beyond the pseudoautosomal region, thus involving heterologous segments of the differential regions, a fact that is clearly evident at the Y centromeric region.
    Type of Medium: Electronic Resource
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