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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Dental traumatology 13 (1997), S. 0 
    ISSN: 1600-0595
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract Dens invaginatus is a developmental variation resulting from an alteration in the normal growth pattern of the dental papilla of a tooth. This anomaly occurs predominantly in maxillary permanent lateral incisors. Multiple occurrence in maxillary incisor teeth in the same patient has frequently been reported, and examination of bilateral teeth for the anomaly is often carried out routinely. This paper reports an unusual case of multiple invaginations, including dens invaginatus affecting maxillary lateral incisors and a supernumerary tooth and minor imaginations of the upper canines. Moreover, the case illustrates the importance of examining all the teeth in patients who present with dens invaginatus and palatal pits in incisors and canines. The possibility that the supernumerary tooth had resulted from gemination of the lateral incisor tooth germ is discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 57 (1991), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: The relationship between oxidative polymorphisms and the cause of Parkinson's disease is controversial. The drug l-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP), which induces parkinsonism in humans and in some animal models, is metabolized by cytochrome P450 db1 isozyme (the same enzymatic system implicated in 4-hydroxylation of debrisoquine). In this study, we treated females of three rat species, which differ in their ability to hydroxylate debrisoquine, with MPTP (three doses of 30 mg/kg s.c. at 12-h intervals), and we measured their motor activity and brain monoamine levels. Female dark-adapted rats (poor metabolizers of debrisoquine) showed a more pronounced and more maintained reduction of their motor activity after treatment with MPTP. MPTP-treated, dark-adapted rats also had a depletion of noradrenaline in the diencephalon and a depletion of dopamine and serotonine and their respective metabolites in the limbic system when compared with the other two species. These results suggest that oxidative polymorphism of debrisoquine plays a role in the acute effects of MPTP.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Terra nova 6 (1994), S. 0 
    ISSN: 1365-3121
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: Principal component analysis (PCA) and correspondence analysis (CA) have been used to identify several critical mineral crystallization factors during metamorphism of Mn-rich lithologies from the Iberian Massif, Spain. Three types of variables have been considered in the system: mineralogical variables, bulk composition variables and one physical variable (oxygen fugacity). PCA was applied to the compositional variables to obtain four components, which were used as new compositional variables. These, together with the mineralogical and physical variables, were treated in the CA. The plot of the variables on the factor 1-factor 2 plane reveals that tephroite crystallization is controlled by a compositional variable representing low values of ratio Si/(Mn+Fe) in the rocks. Moreover, it is possible to deduce from this plot the importance of high oxygen fugacity conditions for the crystallization of piemontite. The third factor shows that the crystallization of spessartine does not require very restrictive physical-chemical conditions.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of advanced nursing 14 (1989), S. 0 
    ISSN: 1365-2648
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The purpose of this paper is to explore and detect possible factors associated with the appearance and maintainance of affective disorders in the elderly, special emphasis was put on anxiety and depression Two hundred and seven Cordobese citizens over 65 years of age, filled in a Hospital Anxiety and Depression Questionnaire and a Habit Behavioural Questionnaire The variables sex, hospitalization and family life were controlled The results emphasize the existence of moderate but significant correlations between depression and certain behavioural habits in the elderly, such as appetite, taking walks and sleeping The greater the appetite, food intake, taking of frequent walks and hours of sleep, the more the association with lower levels of depression in the elderly studied Anxiety, on the other hand, only correlates significantly with behavioural habits related to sleep cycles By means of a urufactorial variance analysis, the differential effect of some of the behavioural habits on the aforementioned disorders is shown Using a multiple regression analysis, results of the behavioural habits, which seem to be the best predictors of anxiety and depression in the elderly, are obtained After a discussion of these results, their possible implications in nursing are analysed and a few interesting conclusions are drawn.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    ISSN: 1473-4192
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Linguistics and Literary Studies
    Notes: The objective of the study is the analysis of private verbal thinking (PVT) during problem-solving activities carried out in a second language, as well as the study of the role that both the L1 and the L2 play in this process. PVT is defined as a particular type of private speech that surfaces during the reasoning process as a tool used in the resolution of problem-solving tasks. This study is based on the comparison of the PVT produced by three different groups of speakers: intermediate-level students of Spanish as an L2, advanced-level speakers of Spanish as an L2, and native speakers of Spanish. In addition to analyzing the general characteristics of this phenomenon, special attention is paid to the use that each of these groups made of their L1 in relation to their L2 during the resolution of a battery of logical, mathematical, and spatial questions. The ultimate goal of this study is to contribute to clarifying the importance of the L1 in an L2 language classroom, as it was found that the L1 manifested itself as a key factor in the process of reasoning.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    ISSN: 1540-8159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Endocardial pacemaker electrode implantation can be difficult in patients with anomalous superior vena cava (SVC). Venography and CAT scan showed that the patient lacked SVC venous drainage and that systemic veins drained into the inferior vena cava through the azygos vein. A temporary stimulation electrode was placed by puncture of the femoral vein, permanent stimulation by venotomy of the epigastric vein, with the electrode inserted through the external iliac vein.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Birth 9 (1982), S. 0 
    ISSN: 1523-536X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: : The relation of reported job commitment to emotions in the third trimester of pregnancy and six weeks postpartum was studied in 120 primiparae. Answers to written questionnaires and telephone interviews were objectively scored and statistically analyzed. The results suggest that women who adapt well to work also adapt well to childbearing. Women who scored high in job commitment had more favorable psychological and emotional experiences in the first pregnancy and postpartum period on some measures, and the degree of job commitment was not related to reported maternal attachment behavior or attitudes. It was also found that women who reported more job interest tended to wait longer before starting a family, worked longer into pregnancy, and planned to return to work sooner postnatally.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 62 (1994), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Neuropeptides were directly detected in single identified neurons and the neurohemal area of peptidergic (neuroendocrine) systems in the Lymnaea brain by using matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS). The samples were placed in matrix solution and ruptured to allow mixing of cell contents with the matrix solution. After formation of matrix crystals, the analytes were analyzed by MALDI-MS. It was surprising that clean mass spectra were produced, displaying extreme sensitivity of detection. In one of the neuroendocrine systems studied, we could demonstrate for the first time, by comparing the peptide patterns of soma and of neurohemal axon terminals, that processing of the complex prohormone expressed in this system occurs entirely in the soma. In the other system studied, novel peptides could be detected in addition to peptides previously identified by conventional molecular biological and peptide chemical methods. Thus, complex peptide processing and expression patterns could be predicted that were not detected in earlier studies using conventional methods. As the first MALDI- MS study of direct peptide fingerprinting in the single neuron these experients demonstrate that MALDI-MS forms a new and valuable approach to the study of the synthesis and expression of bioactive peptides, with potential application to single-cell studies in vertebrates, including humans.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 26 (1976), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: —Measurements of the incorporation of [14C]NaHCO3 into orotic acid, uridine nucleotides and RNA in tissue minces establish the occurrence of the complete orotate pathway for the de novo biosynthesis of pyrimidines in rat brain. Selective inhibition of the incorporation of various radiolabelled precursors into orotic acid by uridine demonstrates the operation of a feedback control mechanism in brain minces and indicates carbamoylphosphate synthetase to be the site of inhibition; purine nucleosides were similarly found to inhibit the de novo biosynthesis of pyrimidines.The activity of the orotate pathway, as assessed by the rate of incorporation of [14C]NaHCO3 into orotic acid, was found to be very high in fetal brain and to decline rapidly with neurological development; the mature rat brain exhibits less than 1% of the activity of the fetal brain at 18 days of gestation. Comparative studies on the ability of minces of the brain and several extraneural tissues to utilize [14C]NaHCO3 and [14C]aspartate as precursors of orotic acid lead us to speculate that variations in the ability of tissues to synthesize orotic acid de novo are determined by similar variations in their ability to synthesize carbamoylphosphate.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 16 (1989), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In the comparison of radiographical findings (flattening, irregular surface and osteophyte formation) between lateral tomography and Orthopantomography(r) in thirty-one female patients with craniomandibular disorders, a 76% similarity was found. A trend in the findings was seen: with an increase in radiographical findings visible in the tomograms there is a decrease in the amount of condylar asymmetry visible in the Orthopantomograms(r) and a decrease in the age of the patients.
    Type of Medium: Electronic Resource
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