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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neuro-oncology 39 (1998), S. 1-18 
    ISSN: 1573-7373
    Keywords: malignant glioma ; cell culture ; CNTF ; LIF ; receptor ; cell growth
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We have established three new cell lines deriving from malignant human gliomas. The cell lines were described in terms of both morphology and growth characteristics. Most cells in all three cell lines expressed the neuroepithelial marker protein GFAP. In terms of growth characteristics, the cells showed only slight differences. The cell lines showed no expression of the neural form of the c-src gene, pp60c-s rcN, but did express the ubiquitous form, pp60c-s rc. The established glioma cell lines were also examined for expression of members of the neuropoietic cytokine family, CNTF and LIF, and their respective receptor components CNTFRα, LIFRβ and gp130. With the exception of CNTFRα both the ligands and their receptor components were expressed in similar amounts in all three cell lines. The presence of ligand and receptor prompted us to study the effects of exogenously supplied factors on the growth of the glioma cell lines. Whereas LIF induced a high c-fos expression, only low c-fos induction was observed upon CNTF treatment. Accordingly, CNTF did not have any noticeable effects on glioma cell growth in culture, while LIF mediated an inhibiting effect on the growth of the three glioma cell lines in culture.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    ISSN: 1420-9039
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    ISSN: 1573-0743
    Keywords: magnetic resonance imaging ; myocardial contraction ; myocardial ischemia ; myocardial perfusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Purpose: The purpose of this study is to assess the reliability of multislice MR perfusion imaging in comparison to regional wall function and nuclear medicine and to test different qualitative and quantitative parameters for perfusion assessment. Material and methods: 15 patients with chronic myocardial ischemia underwent CINE and first-pass perfusion MR imaging. Functional myocardial imaging was performed using a segmented CINE FLASH sequence and systolic myocardial wall thickening was assessed after semiautomated segmentation. MR first-pass perfusion studies were performed using a multislice saturation recovery TurboFLASH sequence. Different parameters were calculated for assessment of hypoperfused segments and results of MR imaging compared to 99mTc-SestaMIBI SPECT. Results: MR perfusion imaging showed a sensitivity of 72% and a specificity of 98%. In combination with MR CINE imaging and wall thickening analysis we calculated a sensitivity of 100% and a specificity of 93%. Qualitative and quantitative perfusion parameter analysis showed significant differences between normal and hypoperfused segments for the signal intensity increase (p 〈 0.001), the signal intensity upslope (p 〈 0.001) as well as for the myocardial mean transit time (p 〈 0.001). Conclusion: The combination of systolic wall thickening analysis and myocardial perfusion can markedly improve the sensitivity of MRI in depiction of LV myocardial perfusion abnormalities. For assessment of hypoperfusion, different quantitative and qualitative parameters can be calculated showing significant differences between normal state and hypoperfusion.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    ISSN: 0570-0833
    Keywords: carbenes ; cyclopropenes ; rearrangements ; strained molecules ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    ISSN: 0570-0833
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 109 (1997), S. 1689-1692 
    ISSN: 0044-8249
    Keywords: Carbene ; Cyclopropene ; Gespannte Ringe ; Umlagerungen ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    ISSN: 0941-1216
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Hydrolytic Stable Ammonium Salts of Sulfonated Organic Phosphites and their Use as Cocatalysts in the Rhodium-catalyzed Hydroformylation of OlefinsAmmonium salts of sulfonated organic phosphites, which are resistant to hydrolysis, have been prepared by transesterification of triphenylphosphite with mono-ammonium salt of p-hydroxyphenylsulfonic acid in yields between 66 and 76%. A mixture containing triisooctylammonium salts of sulfonated triphenylphosphite [TPPp-SO3HN(i-octyl)3] was submitted to a test for stability to hydrolysis. The time required for hydrolysis of 7.4% of the TPPp-SO3HN(i-octyl)3 was 3 hours under drastic conditions. Triphenylphosphite was in the same test hydrolyzed quantitatively within three hours.Tetradec-1-ene was hydroformylated by means of the catalytic systems consisting of rhodium-2-ethylhexanoate with either TPPp-SO3HN(i-octyl)3, triphenylphosphite (TPPp) or triphenylphosphine (TPP) at 125°C, 0.6 MPa and a rhodium concentration of 50 ppm. Higher reaction selectivities for linear aldehydes were achieved with the rhodium/TPPp-SO3HN(i-octyl)3 catalytic system. Reaction rates increased with the Rh/TPPp-SO3HN(i-octyl)3 catalyst at lower temperature (110°C). Using this catalyst at 110°C, higher yields are achieved than with the Rh/TPP or Rh/TPPp catalysts.Hex-1-ene was hydroformylated by using the catalytic systems Rh4(CO)12 with TPPp-SO3HN(i-octyl)3, Rh4(CO)12 TPP or Rh4 (CO)12 with TPPp at 125°C, 2,5 MPa and a rhodium concentration of 20 ppm. This confirms the above experiments which indicated that higher linear: branched aldehyde ratios were obtained with the rhodium/TPPp-SO3HN(i-octyl)3 catalyst.
    Additional Material: 5 Tab.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Company
    Nature biotechnology 14 (1996), S. 71-76 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Endo cellulases of plant pathogenic erwinias degrade cellulose as well as the cellulosic domains of barley (1-3,1-4)-β-glucan. Depolymerization of the latter substrate is mainly caused by (1-3,1-4)-β-glucanases, which hydrolyze (1-4)-β glycosidic linkages adjacent to (1-3)-β ...
    Type of Medium: Electronic Resource
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