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  • 2005-2009  (83)
  • 1945-1949  (1)
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  • 1
    Online Resource
    Online Resource
    Basel : Karger
    Part of " Monographs in clinical cytology"
    Keywords: Gebärmutterschleimhaut ; Adenocarcinom ; Cytodiagnostik ; Anatomy ; Cytology ; Gynecology ; Oncology ; Pathology ; Preventive Medicine ; Gebärmutterschleimhaut ; Adenocarcinom ; Cytodiagnostik
    Abstract: The incidence of endometrial adenocarcinoma, the most common malignant tumor of the female genital tract in developed countries, has increased over recent years. A variety of collection techniques are available to obtain cytologic or histopathologic samples for its diagnosis but their interpretation can be difficult without proper collection and preparation. However, this monograph, written by internationally recognized experts, is a most valuable educational resource for the pathologist and cytopathologist in the techniques of endometrial sampling and diagnosis. The chapters are comprehensive and logically organized, covering the epidemiology and pathogenesis of endometrial adenocarcinoma, endometrial sampling techniques and the spectrum of cytomorphologic appearance from benign through hyperplasia to adenocarcinoma of the endometrium. A separate chapter covers non-epithelial uterine malignancies. Throughout the monograph, inclusion of both cytologic and H&E histologic images allows cytohistologic correlation of lesions. In summary, this endometrial handbook seeks to clarify a difficult area of cytodiagnosis and will become an important reference text for cytopathologists, pathologists and cytotechnologists
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource
    ISBN: 9783805584807 , 9783805584814
    Series Statement: Monographs in clinical cytology 17
    DDC: 616.99/465
    RVK:
    Language: English
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  • 2
    Online Resource
    Online Resource
    Boston : Martinus Nijhoff Publishers
    Keywords: Europäische Union. Mitgliedsstaaten ; International and municipal law / European Union countries
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (689 p.) , 25 cm
    ISBN: 9789047411161
    RVK:
    Language: English
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Munksgaard International Publishers
    Journal of pineal research 38 (2005), S. 0 
    ISSN: 1600-079X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract:  The aim of this study was to determine the effects of melatonin on proinflammatory status of rats with collagen-induced arthritis (CIA). CIA was induced in male Wistar rats with an emulsion of type II collagen in Freund's Incomplete Adjuvant (C-II/FIA). For 14 days, control and pinealectomized rats received a subcutaneous injection of 100 μL melatonin (30 μg) or vehicle (saline on 1% ethanol). Levels of cytokines interleukin (IL)-1β and IL-6 were determined in the serum, peripheral blood mononuclear cells, and joints. Levels of anti-type II collagen antibody, nitrite/nitrate, and lipid peroxidation (LPO) were determined in the serum, joints, and brain. Treatment with melatonin significantly increased the levels of IL-1β, IL-6, nitrite/nitrate and LPO in joints. However, melatonin significantly reduced the levels of nitrite/nitrate and LPO in serum and brain. Moreover, CIA in pinealectomized rats presented significantly reduced levels of IL-1β and IL-6, titers of anti-type II collagen antibodies, levels of nitrite/nitrate, and LPO in joints but elevated levels in serum and brain. Melatonin has been described as a proinflammatory and antioxidant agent. In a process of inflammation as CIA, melatonin acts with a markedly proinflammatory effect at local and peripheral levels maintaining its antioxidant effect only at peripheral level.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Munksgaard International Publishers
    Journal of pineal research 39 (2005), S. 0 
    ISSN: 1600-079X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract:  To gain insight into the relationship between thymus and pineal gland during rat development, the melatonin content as well as the activity and expression of the two key enzymes for melatonin biosynthesis, i.e. N-acetyltransferase (NAT) and hydroxyindole-O-methyltransferase (HIOMT), were studied in the thymus at fetal and postnatal stages. Moreover, melatonin-membrane receptor (MT1) expression was also analyzed. We found both the expression and activity of thymic NAT and HIOMT at 18 days of fetal life. Additionally, there is production of melatonin in the thymus as well as MT1 expression at this fetal age. These results show values higher in day-time than at night-time. The pineal gland begins to produce significant levels of melatonin around postnatal day 16, and this synthesis shows a circadian rhythm with high values during the dark period; therefore the nocturnal serum melatonin may inhibit thymic melatonin production. To document this, we report an increased melatonin content of the thymus in pinealectomized rats compared with sham-pinealectomized. In conclusion, these results show, for the first time, the presence of the biosynthetic machinery of melatonin and melatonin production in developing rat thymus and that the pineal gland may regulate this process.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    International journal of manpower 26 (2005), S. 364-381 
    ISSN: 0143-7720
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Purpose - This study aims to analyse the relationship between innovation and human resource management (HRM) from an empirical perspective, attempting to establish whether innovation determines the firm's HRM or conversely HRM influences the innovation level of the company Design/methodology/approach - Literature is reviewed from both theoretical and empirical perspectives. On the basis of this review, some research hypotheses are formulated. Finally, these hypotheses are empirically tested on a sample of Spanish firms. Findings - The results provide evidence for both hypotheses and offer more support for Schuler and Jackson's model than for Miles and Snow's model. In accordance with the previous literature, that in order to affect employee behaviour - and consequently promote company objectives - firms must develop a bundle of internally consistent HRM practices. However, what is still unresolved is which HRM practices should be included in that system. Originality/value - Fills a gap in the literature, particularly in empirical research, with a focus on Spanish firms.
    Type of Medium: Electronic Resource
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  • 6
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    Unknown
    Louvain-la-Neuve: European Regional Science Association (ERSA)
    Publication Date: 2015-09-11
    Description: The study of corruption is attracting lot of attention in recent years. Focusing on the economic consequences of corruption, the empirical evidence points to a positive relation between institutional integrity, or absence of corruption, and economic growth. Although most developed countries tend to have lower corruption than less developed ones, there exists significant variation within OECD countries. As an example, it may be observed that the gap in perceived corruption between the Nordic countries and southern Europe is larger than the gap between southern Europe and the average of the emerging economies. In this context, the objective of this paper is to analyze the impact of corruption on economic performance in a sample of OECD countries during the period 1980-2000. Specifically, we study the effect of corruption on productivity and efficiency change, trying to determine whether productivity growth is greater in countries with lower corruption. To this end, different productivity measures are compared by considering both output per worker and Total Factor Productivity (TFP). Furthermore, TFP change is decomposed into efficiency change and technological progress by means of Malmquist productivity indices. On the basis of this of this decomposition we will analyze whether corruption affect TFP growth via efficiency gains or technological change, thus gaining insight into the channels through which corruption influence economic growth.
    Keywords: ddc:330
    Language: English
    Type: doc-type:conferenceObject
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  • 7
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    Unknown
    La Plata: Universidad Nacional de La Plata, Centro de Estudios Distributivos, Laborales y Sociales (CEDLAS)
    Publication Date: 2016-02-18
    Description: This paper takes advantage of a new source of information – the Gallup World Poll 2006 – to estimate and characterize income poverty and inequality in Latin America and the Caribbean (LAC) at the country level, and to compare LAC estimates to those in other regions of the world. The Gallup survey has the advantage of being conducted in over 130 nations with almost the same questionnaire in all countries, and then it stands as a complement to national household surveys for international comparison purposes.
    Keywords: ddc:330 ; Einkommensverteilung ; Intergenerationale Übertragung ; Argentinien
    Language: Spanish
    Type: doc-type:workingPaper
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 92 (2005), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Insulin-like growth factor-I (IGF-I) has protective effects against β-amyloid (Aβ)-induced neuronal cell death. Because alterations of the somatostatinergic system have been described in Alzheimer's disease, we investigated the effects of the Aβ peptide and the possible protective role of IGF-I on the somatostatinergic system of the rat temporal cortex and on cell death and phosphorylated (p)-Akt levels in this area. Aβ25–35 was administered intracerebroventricularly to male rats via an osmotic minipump over 14 days (300 pmol/day). Another group received a subcutaneous IGF-I infusion (50 μg/kg/day), concomitant with Aβ25–35 administration, whereas a third group received IGF-I alone. Aβ25–35 significantly decreased the somatostatin (SRIF)-like immunoreactive content and the SRIF receptor density, as a result of a decrease in the levels of the SRIF receptor subtype 2. The inhibitory effect of SRIF on adenylyl cyclase activity was significantly lower after Aβ25–35 infusion, whereas the levels of the inhibitory G protein subunit Giα1, Giα2 or Giα3 were unaltered. Cell death was increased and p-Akt levels decreased in Aβ25–35-treated animals. IGF-I administration increased immunoreactive IGF-I levels in the temporal cortex and restored all parameters affected by Aβ25–35 to baseline values. These findings suggest that IGF-I prevents the deleterious effect of Aβ25–35 on the somatostatinergic system.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    ISSN: 1365-2621
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: A puffed product was made by extruding corn flour supplemented with soybean and safflower pastes. Mixes with the following proportions of corn flour, soybean and safflower pastes: (i) 89:8:3, (ii) 83:11:6 and (iii) 80:17:3 were extruded. The corn flour, soybean and safflower pastes used had 6.6%, 45.9% and 32.9% protein content respectively. In addition, the soybean paste contained 11.78 units of inhibited trypsin/mg of sample, which means it was appropriate for human consumption. Sensory evaluation of extruded products showed that there were no significant differences in flavour, crunchiness and acceptance in the case of products 1 and 3, when compared with samples made from corn flour alone. Product 2 had lower scores, as it had a bitter taste because of the greater amount of safflower paste used. Biological testing showed that all the products containing soybean and safflower pastes were superior to the 100% corn diet in terms of food conversion, growth rate and weight gain.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    ISSN: 1365-2621
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: The effects of low temperature blanching in calcium chloride solution of jalapeño peppers prior to freezing, on firmness retention, pH, methanol, colour and calcium ions of the product, were evaluated by response surface methodology. Texture, methanol content and pH were affected by all of the variables studied (P = 0.05). The optimum response was obtained at temperatures of 63.3–66 °C, calcium chloride concentrations of 0.17–0.21 m, immersion time of 11.6–14.4 min, with a holding time after blanching of 56.6–66.1 min. Microscopic evaluation of the thawed pepper showed that blanching in CaCl2 solution provided a protective effect in maintaining cell wall integrity.
    Type of Medium: Electronic Resource
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