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  • Biochemistry and Biotechnology  (39)
  • Deutschland  (15)
  • 1955-1959  (54)
Collection
Language
Years
Year
  • 1
    Journal/Serial
    Journal/Serial
    Köln : Heymanns | Detmold ; Köln ; Berlin : Heymanns | Köln ; Berlin : Heymanns ; 65.1950,7(Apr.) -
    Keywords: Verwaltung ; Verwaltungsrecht ; Deutschland ; Zeitschrift ; Zeitschrift ; Deutschland 03.10.1990- ; Verwaltung ; Verwaltungsrecht ; Zeitschrift
    Type of Medium: Journal/Serial
    Pages: 30 cm
    ISSN: 0012-1363 , 0012-1363
    RVK:
    Former Title: Deutsches Verwaltungsblatt vereinigt mit Deutsche Verwaltung
    Language: German
    Note: Ersch. 14-tägl.
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  • 2
    Journal/Serial
    Journal/Serial
    Stuttgart [u.a.] : Kohlhammer ; 1.1948,Okt. -
    Keywords: Öffentliches Recht ; Verwaltungslehre ; Verwaltungsrecht ; Verwaltung ; Verwaltungsrecht ; Deutschland ; Zeitschrift ; Zeitschrift ; Zeitschrift ; Zeitschrift ; Öffentliches Recht ; Zeitschrift ; Verwaltungslehre ; Verwaltungsrecht ; Zeitschrift ; Deutschland 03.10.1990- ; Verwaltung ; Verwaltungsrecht ; Zeitschrift
    Type of Medium: Journal/Serial
    ISSN: 0029-859X
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    Language: German
    Note: Ersch. 2x monatl.
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  • 3
    Journal/Serial
    Journal/Serial
    München ; Frankfurt, M. : Beck | München ; Berlin : Biederstein ; 1.1947/48 -
    Keywords: Recht ; Recht ; Rechtswissenschaft ; Rechtsprechung ; Deutschland ; Deutschland ; Zeitschrift ; Zeitschrift ; Zeitschrift ; Deutschland 03.10.1990- ; Recht ; Zeitschrift ; Deutschland 03.10.1990- ; Recht ; Rechtswissenschaft ; Rechtsprechung ; Zeitschrift
    Type of Medium: Journal/Serial
    Pages: 30 cm
    Edition: München ; Frankfurt, M. Beck 1985
    ISSN: 0341-1915 , 0341-1907 , 0341-1915 , 0341-1907
    DDC: 349.4305
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    Former Title: Fünfjahresregister
    Language: German
    Note: Mikrofiche-Ausg.: München ; Frankfurt, M. : Beck, 1985
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  • 4
    Journal/Serial
    Journal/Serial
    Wuppertal : Kommunalverl. Fachverl. für Kommunalwirtschaft u. Umwelttechnik | Düsseldorf : Deutscher Kommunalverl. ; 1953/54 -
    Keywords: Gemeindewirtschaft ; Deutschland ; Zeitschrift ; Zeitschrift ; Deutschland 03.10.1990- ; Gemeindewirtschaft ; Zeitschrift
    Description / Table of Contents: Die kommunale Technik
    Type of Medium: Journal/Serial
    ISSN: 0450-7169 , 0450-7169
    DDC: 352.14
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    Language: German
    Note: 2003,8 fälschlich als Heft 8/9 bez.; 2018,5 nicht erschienen; monatl.
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  • 5
    Journal/Serial
    Journal/Serial
    Düsseldorf : Handelsblatt Fachmedien | Düsseldorf ; Frankfurt, M. : Verl.-Gruppe Handelsblatt | Düsseldorf : Handelsblatt | Düsseldorf : Verl.-Gruppe Handelsblatt ; 1.1948 -
    Keywords: Unternehmensrecht ; Betriebswirtschaftslehre ; Betriebsführung ; Steuerrecht ; Arbeitsrecht ; Wirtschaftsrecht ; Deutschland ; Deutschland ; Zeitung ; Deutschland 03.10.1990- ; Unternehmensrecht ; Betriebswirtschaftslehre ; Deutschland 03.10.1990- ; Betriebsführung ; Steuerrecht ; Arbeitsrecht ; Wirtschaftsrecht
    Description / Table of Contents: IBZ - Internationaler betriebswirtschaftlicher Zeitschriftenreport; IBZ-Schlagwortregister; ab 1983: IBZ-Titeldokumentation; 2010 - 2011,Juni u. ab 2014: Standpunkte; ab 2011: Vorsorge und Risikoabsicherung; IT-Guide
    Type of Medium: Journal/Serial
    ISSN: 0005-9935 , 0005-9935
    DDC: 346.4306505
    Former Title: DB
    Language: German
    Note: 56.2003,1 fälschlich als Jg. 55 bez.; 59.2006,1-3 fälschlich als Jg. 58 bez.; Periodizität: wöchentl.
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  • 6
    Journal/Serial
    Journal/Serial
    Wiesbaden : Harrassowitz | Leipzig ; 1.1902 - 33.1942(1943); 34.1950 - 55.1993; 56.1995/96(1995) -
    Keywords: Bibliotheksführer ; Bibliothekar Lexikon, Wörterbuch ; Wissenschaftliche Bibliothek Lexikon, Wörterbuch ; Bibliothek ; Verzeichnis ; Bibliothek ; Verzeichnis ; Bibliothekar ; Höherer Dienst ; Verzeichnis ; Bibliothekar ; Höherer Dienst ; Wissenschaftliche Bibliothek ; Deutschland (Bundesrepublik) ; Deutschland ; Deutschland ; Deutschland ; Deutschland ; Biographie ; Adressbuch ; Zeitschrift ; Verzeichnis ; Biografie ; Adressbuch ; Führer ; Wörterbuch ; Deutschland 〈Bundesrepublik〉 23.05.1949-02.10.1990 ; Bibliothek ; Verzeichnis ; Deutschland 03.10.1990- ; Bibliothek ; Verzeichnis ; Deutschland 03.10.1990- ; Bibliothekar ; Höherer Dienst ; Verzeichnis ; Deutschland 03.10.1990- ; Bibliothekar ; Höherer Dienst ; Biographie ; Deutschland 03.10.1990- ; Wissenschaftliche Bibliothek ; Adressbuch
    Description / Table of Contents: Betriebsstatistik
    Type of Medium: Journal/Serial
    ISSN: 0075-2215 , 0075-2223
    RVK:
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    Language: German
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  • 7
    Journal/Serial
    Journal/Serial
    Witten : Mendel | Hamburg : Handelskammer | Hamburg : Dieckmann ; Nachgewiesen 2.1924 -
    Keywords: Aussenhandel ; Aussenhandel Recht ; Außenhandelsrecht ; Deutschland ; Formularsammlung ; Zeitschrift ; Zeitschrift ; Formularsammlung ; Deutschland 03.10.1990- ; Außenhandelsrecht ; Formularsammlung ; Zeitschrift
    Type of Medium: Journal/Serial
    Pages: 23 cm
    ISSN: 0173-718X , 0173-718X
    DDC: 343.43087
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    Language: German
    Note: Ersch. unregelmäßig
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  • 8
    Journal/Serial
    Journal/Serial
    Köln : ˜O.œ Schmidt | Bleckede : Meissner | Hamburg : Verl. Deutsche Rechtsprechung | Hamburg : Monatsschrift f. Dt. Recht-Verlagsges. | Köln ; Hamburg : ˜O.œ Schmidt ; 1.1947,Apr. -
    Keywords: Deutschland (Bundesrepublik) ; Entscheidungssammlung Periodika ; Bürgerliches Recht ; Rechtsprechung ; Deutschland ; Zeitschrift ; Zeitschrift ; Zeitschrift ; Entscheidungssammlung ; Deutschland 03.10.1990- ; Bürgerliches Recht ; Zeitschrift ; Rechtsprechung ; Zeitschrift
    Description / Table of Contents: MDReport; Sonderbeil.; Sonderheft
    Type of Medium: Journal/Serial
    ISSN: 0340-1812 , 0340-1812
    DDC: 346.43005
    Language: German
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  • 9
    Journal/Serial
    Journal/Serial
    München ; Frankfurt, M. : Verl. Beck | Berlin : Heymanns | Leipzig ; Berlin : Verl. Chemie | Weinheim, Bergstr. : Verl. Chemie | Weinheim : Wiley-VCH-Verl. | München ; Frankfurt, M. ; Berlin : Verl. Beck ; 1.1896 - 49.1944,5/9; 50.1948 -
    Keywords: Gewerblicher Rechtsschutz ; Urheberrecht ; Gewerblicher Rechtsschutz ; Urheberrecht ; Deutschland ; Deutschland ; Zeitschrift ; Zeitschrift ; Zeitschrift ; Zeitschrift ; Deutschland 03.10.1990- ; Gewerblicher Rechtsschutz ; Zeitschrift ; Deutschland 03.10.1990- ; Urheberrecht ; Zeitschrift ; Gewerblicher Rechtsschutz ; Urheberrecht ; Zeitschrift
    Description / Table of Contents: Neue Entscheidungen des BGH; ab 81.1979: Leitsätze neuer Entscheidungen des BGH
    Type of Medium: Journal/Serial
    Pages: 30 cm
    ISSN: 0016-9420 , 0016-9420
    DDC: 346.4304805
    RVK:
    Language: German
    Note: Ersch. monatl.
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  • 10
    Journal/Serial
    Journal/Serial
    Bielefeld : UVW, Univ.-Verl. Webler | Neuwied : Luchterhand | Berlin : Dt. Verl. d. Wiss. ; 1.1953/54; 2.1954 -
    Keywords: Hochschule ; Deutschland ; Zeitschrift ; Zeitschrift ; Deutschland 03.10.1990- ; Hochschule ; Zeitschrift
    Description / Table of Contents: Suppl.; 42.1994,6: Didacta 95
    Type of Medium: Journal/Serial
    ISSN: 0018-2974 , 0018-2974
    DDC: 378.4305
    RVK:
    Former Title: Monatsschrift für Fragen der Hochschulpolitik, Lehrmethodik und Hochschulorganisation
    Language: German
    Note: Ersch. bis 38.1990 monatl., 39.1991 - 42.1994 zweimonatl.; 13.1965,1-4 im Inhaltsverz. als Jg. 14 gez.; Jg. 56.2008,1 teils fälschlich als Jg. 55 bez.
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  • 11
    Journal/Serial
    Journal/Serial
    Hiltrup : Landwirtschaftsverl. | Bochum : DAV | München : BLV Verl.-Ges. ; Aufl. [1.]1941; 2.1948 - 7.1974; 13.2005 -
    Keywords: Europäische Union ; Landwirtschaft ; Deutschland ; Statistik ; Zeitschrift ; Statistik ; Europäische Union ; Deutschland 03.10.1990- ; Landwirtschaft ; Statistik
    Type of Medium: Journal/Serial
    Language: German
    Note: Ersch. unregelmäßig
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  • 12
    Journal/Serial
    Journal/Serial
    Frankfurt, M. : Dt. Fachverl. | Heidelberg : Verl. Recht und Wirtschaft | Frankfurt, M. : Verl. Recht und Wirtschaft ; 1.1954/55 - 3.1957,12; 21.1975 -
    Keywords: Internationales Wirtschaftsrecht ; Wirtschaftsrecht ; Deutschland ; Zeitschrift ; Zeitschrift ; Zeitschrift ; Deutschland 03.10.1990- ; Internationales Wirtschaftsrecht ; Zeitschrift ; Wirtschaftsrecht ; Zeitschrift
    Description / Table of Contents: Leasing; 32.1986: Kapitalanlage; Versicherung; ab 33.1987: Leasing-Berater; Versicherungs-Berater; Finanz-Berater; ab 35.1989: Betriebs-Berater international; 35.1989 - 36.1990: Organisations-Berater; ab 43.1997: Leasing- und Finanz-Berater; Banken & Versicherungen; ab 46.2000: Computer Praxis & Recht; ab 50.2004: EU-Erweiterungs-Report; RIW-Special; ab 63. Jg. (2017): Beihefter
    Type of Medium: Journal/Serial
    ISSN: 0340-7926 , 0340-7926
    DDC: 343.0705
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    Language: German
    Note: Ersch. monatl., früher vierteljährl.
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  • 13
    Journal/Serial
    Journal/Serial
    Frankfurt, M. : VDMA-Verl. | Frankfurt, M. : Maschinenbau-Verl. ; 1952 -
    Keywords: Maschinenbauindustrie ; Maschinenbauindustrie ; Anlagenbau ; Maschinenbau ; Deutschland (Bundesrepublik) ; Deutschland ; Statistik ; Statistik ; Statistik ; Statistik ; Zeitschrift ; Statistik ; Deutschland 〈Bundesrepublik〉 23.05.1949-02.10.1990 ; Maschinenbauindustrie ; Statistik ; Deutschland 03.10.1990- ; Maschinenbauindustrie ; Statistik ; Anlagenbau ; Statistik ; Maschinenbau ; Statistik
    Type of Medium: Journal/Serial
    RVK:
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    Language: German
    Note: Teils mit Zählung; jährl.
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  • 14
    Journal/Serial
    Journal/Serial
    Bonn : Festland-Verl. | Bonn : Nfa Vertriebs- u. Werbeges. | Bonn : Verl. Europapress | Baden-Baden ; Bonn ; Frankfurt, M. : Lutzeyer | Bonn : Europa-Verl. ; [1.]1950; 2.1952 - 28.1978; 29.1979/80(1979) - 52.2002/03(2002); 53.2004(2003)-67. Jahrgang (2018)
    Keywords: Öffentlichkeit ; Einrichtung ; Öffentlichkeit ; Einrichtung ; Deutschland ; Deutschland (Bundesrepublik) ; Adressbuch ; Adressbuch ; Zeitschrift ; Verzeichnis ; Adressbuch ; Deutschland 03.10.1990- ; Öffentlichkeit ; Einrichtung ; Adressbuch ; Deutschland 〈Bundesrepublik〉 23.05.1949-02.10.1990 ; Öffentlichkeit ; Einrichtung ; Adressbuch
    Type of Medium: Journal/Serial
    ISSN: 0082-1829
    RVK:
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    Language: German
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  • 15
    Journal/Serial
    Journal/Serial
    Düsseldorf : Verlagsgr. Handelsblatt | Düsseldorf : Arbeitgeber-Verl. Ide | Köln : Bachem ; [1.]1949 - [3.]1951; 4.1952 - 63.2011,7/8; damit Ersch. eingest.
    Keywords: Bundesvereinigung der Deutschen Arbeitgeberverbände ; Management ; Betriebliche Sozialpolitik ; Arbeitsrecht ; Wirtschaftspolitik ; Zeitschrift ; Sozialpolitik ; Zeitschrift ; Arbeitsrecht ; Zeitschrift ; Arbeit ; Zeitschrift ; Arbeitgeber ; Deutschland ; Deutschland ; Deutschland ; Zeitschrift ; Zeitschrift ; Zeitschrift ; Zeitschrift ; Zeitschrift ; Zeitschrift ; Deutschland 03.10.1990- ; Management ; Zeitschrift ; Deutschland 03.10.1990- ; Betriebliche Sozialpolitik ; Zeitschrift ; Deutschland 03.10.1990- ; Arbeitsrecht ; Zeitschrift ; Wirtschaftspolitik ; Zeitschrift ; Sozialpolitik ; Zeitschrift ; Arbeitsrecht ; Zeitschrift ; Arbeit ; Zeitschrift ; Arbeitgeber ; Zeitschrift ; Bundesvereinigung der Deutschen Arbeitgeberverbände ; Zeitschrift
    Type of Medium: Journal/Serial
    Pages: 30 cm
    ISSN: 0402-7787
    RVK:
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    Former Title: ˜Derœ Arbeitgeber
    Language: German
    Note: Anfangs vierzehntägl., später monatl.
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  • 16
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 17
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The effects of pH and concentration on foam separation of the protein bovine serum albumin (BSA) from solution has been studied. All results agree, at least qualitatively, with theory. BSA maximum enrichments were observed at the isoelectric pH and enrichment ratio was found to increase with decreasing protein concentrations.
    Additional Material: 5 Ill.
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  • 18
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Most of the free fluid can generally be expressed from fibrous pulps in a few seconds at 50 lb/in2 if the layer of pulp is kept thinner than 1 in. after it has been pressed, and if the fluid is allowed to run away freely. The need for this time and the frictional properties of many pulps are serious obstacles to the design of any strictly continuous press. Roller presses do not allow enough time, screw expellers create too much friction, continuous centrifuges and some other arrangements are intricate and vulnerable.An intermittent but automatic press which avoids these defects is described. In this the material on a perforated conveyor is pressed by a ram and then moved forward as the ram lifts. One such machine has already been made. An outline is given of the principles on which an improved design will depend.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
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  • 19
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Equipment has been developed in which fermentation processes for fastidious, pathogenic micro-organisms can be operated on a pilot-plant scale. Experience has shown the need for the development of concepts, techniques, and equipment meeting more stringent requirements than those ordinarily encountered in the fermentation industry. A system has been developed for the preparation of pure cultures which may be used either for the development of processes or in the preparation of substantial quantities of pure cultures. The equipment includes specially designed valves, fermentors, piping arrangement, and requires special methods of operation in order to maintain pure cultures during growth of the organism. The number of cultures of pathogenic, fastidious micro-organisms contaminated in the systems commonly used in industry is materially greater than the number of contaminated cultures produced in the system described.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 20
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The results of a study on the surface electric charge carried by fresh-water planktonic algae are used to provide a theory for the flocculation of algae with chemical coagulants. Where it is desirable to remove algae from water, for example from lakes or reservoirs for water supply, or from sewage oxidation ponds, the theory indicates certain practices are desirable to obtain the best removal. It is planned to extend the theory and experimental work to cover the removal of untreated algae from water by filtration through porous granular media, believed to be an adsorptive effect. Separation of different species of algae employing their electrokinetic properties is also described.
    Additional Material: 5 Ill.
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  • 21
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A strain of C. purpurea has been isolated which will produce L-tryptophan from indole in submerged culture.The L-tryptophan produced is extracellular and in a free form.Levels of up to 1·5 mg/ml of L-tryptophan have been obtained.
    Additional Material: 4 Ill.
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  • 22
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: An apparatus is described in which large numbers of algal cultures can be maintained under the following conditions: (1) Constant temperature within the range 5 to 70°C, four different temperatures being maintained simultaneously; (2) uniform illumination at intensities up to 20,000 metre-candles; (3) continuous shaking at variable speed; and (4) aeration under aseptic conditions with mixtures of up to four different gases in any desired proportions.Among other features, thermoregulator heads, flow-meters and heaters for sterile filters, of improved design are described.To illustrate the use of the apparatus, data showing the effects of light intensity and temperature on the growth of Monodus subterraneus are presented.
    Additional Material: 8 Ill.
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  • 23
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The nature of the problem of mould growth on baked products is discussed. Existing information on the reduction of this source of wastage by chemical and irradiation techniques is briefly reviewed, and new experimental evidence is presented relating to the use of these procedures. The effectiveness of ionizing radiations in preventing mould growth is indicated but there are many problems to be considered before it can be regarded as a satisfactorily established technique.
    Additional Material: 4 Tab.
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  • 24
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 25
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Fractions of markedly different protein contents may be obtained by air-classifying flour (in the sub-sieve range) at cut sizes of about 17 and 35 μ respectively. Of these fractions, the fine, 1 (of high protein content), contains fragments of interstitial endosperm protein and small starch granules; the intermediate, 2 (low protein), mainly large starch granules; the coarse, 3, fragments of endosperm cells. The yields and protein contents of the fractions vary with different wheats; the yields of 1 and 2 may be greatly increased through suitably grinding the flour after milling.In general, 1 may be used for raising the protein content of flours deficient in protein to a level suitable for bread-making. The amount of 1 required depends on its protein contents and on whether it came from a hard or soft wheat, the hard wheat fraction having better bread-making qualities. The resulting variation in the proportion of 1 required in the blend causes variation in the proportion of other particulate materials introduced with 1, in which they have become concentrated during the air classification. These include diastatically active agents and finely divided discolouring matter; the level of the former reached in the blend greatly affects its bread-making value. Pre-grinding of the flour may be helpful in this respect.When chlorinated, 2 is potentially useful for making light-structured cakes, but hard English wheats have mainly given less satisfactory results than soft. Under certain conditions, 3, with or without 2, may be better for biscuit-making than the parent flour.
    Additional Material: 4 Ill.
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  • 26
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Information on a reliable method for determining the nutritive value of existing and experimental peptones is lacking in the literature. To overcome this handicap, a method for comparative evaluation of microbiological peptones has been developed.The method is based on measuring the growth of eight carefully selected, fastidious, test cultures. The cultures are grown in presence and absence of yeast extract in an inorganic basal medium containing test peptone and a low and high level of glucose.Statistical analysis of replicate peptone evaluations of six peptones, conducted over a period of six months, shows that 95 per cent confidence limits for this method are ± 2·5 to 7·9 per cent of the mean.Four criteria are employed for determining the overall performance of 12 widely used, commercial peptones.The method is very sensitive for detecting differences between batches of commercial peptones. With the aid of this method a new peptone ‘N-Z-Amine YT’ has been developed. Considering performance and relative cost, this peptone is the most economical of the peptones evaluated.
    Additional Material: 2 Ill.
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  • 27
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The influence of mechanical agitation in aerobic fermentations is felt mainly through increased aeration efficiency. For yeast propagations in which oxygen supply is abundant - and presumably not limiting to growth - a specific, but limited, effect of fluid agitation on growth rate has been demonstrated. The improved growth rate is attributed primarily to better mixing of the entire fluid mixture rather than to improved cell-fluid mass transfer.
    Additional Material: 6 Ill.
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  • 28
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Applying radio-isotope 32P, the distribution of bacterial cells retained within glass-fibre air sterilization filters was measured. In particular, the time-dependence of the radial as well as the longitudinal distribution was studied. The collection efficiency of glass-fibre was obtained and the experimental result was compared with a theoretical value based upon the sum of interception, inertia and diffusion. Discrepancies could not be accounted for and are similar to those in the literature. An equation was proposed for the estimation of air filter life. This was not completely verified but leads to some suggestive results.
    Additional Material: 6 Ill.
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  • 29
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: An analysis of the organic constituents of whole, domestic sewage was made by analysing four physically separated fractions. Settlement, centrifuging and filtration were used to obtain one liquid and three solid fractions. Concentration of the filtrate was achieved by freeze-drying with only minor changes in composition. The average concentration of organic carbon in fresh, whole domestic sewage was 310 p.p.m., of which about 70 per cent was in suspension. Eight classes of compounds were found, on analysis, to comprise about 75 per cent of the organic carbon in whole sewage and of the soluble organic carbon 80 per cent was distributed between five groups. Using chromatographic methods the concentrations of four volatile acids were determined and the presence of other acids was detected. Similarly, seven of the soluble sugars and eight present in hydrolysed suspended solids have been identified. The probable nature of some of the compounds unaccounted for is discussed.
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    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A study of factors affecting the reproducibility and yields in cultivations of H. pertussis (the whooping cough organism). The search for suitable media led to the development of a new kind of blood medium suitable for pre-cultures. Sterility of the blood additive could be ensured by filtration, and contamination on starting the freeze-dried cells was avoided by the use of a special kind of ampoule.In the course of studies of different cultivation techniques a 6,000 ml ‘pulsaerator’ was found to be ideal for the preparation of ordinary small batches. Inoculation density, aeration and other factors affecting the yield were studied and a culture cycle suitable for preparing 500 l. batches was developed.
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    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The mathematical theory of the sedimentation type of centrifuge is developed in terms of unhindered settling of a single particle that has reached equilibrium velocity. From this is derived the sigma value for several of the different forms of sedimentation type centrifuge which is the calculated equivalent area of a settling tank theoretically capable of doing the same amount of work in a unit gravitational field. The limitations controlling the accuracy of scale up between centrifuges of similar geometry and between centrifuges of substantially different geometry are discussed.
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    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The mathematical relationship between the throughput of a batch centrifuge and its mechanical characteristics has been applied to the scale-up of one of the steps in virus processing for possible application to the production of vaccines and similar antigens. Slurries that contained a test virus were purified in a laboratory centrifuge. The Q/Σ relationship, developed by Ambler, was used to predict the operating conditions of a larger centrifuge in order to achieve the same clarification of slurry as that produced in the laboratory centrifuge. A correlation between conditions of centrifugation and amount of virus removed from the feed to the centrifuge shows that there is a well-defined Q/Σ value at which significant concentrations of the test virus are sedimented.
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    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A process is described for the extraction of co-enzyme A from dried yeast. It involves cold water extraction, charcoal adsorption followed by pyridine elution, preparation of an acetone power, co-precipitation as the double cuprous complex with glutathione and removal of the glutathione by means of an ion exchange resin.Improvements over previous processes include use of drum dried yeast plus cold extraction resulting in easy filtration and increase of throughput by a factor of three to five, together with the elimination of the ion exchange step formerly thought necessary to remove zine before the co-precipitation stage. Under the best conditions yields represent 30% recovery of the co-enzyme A in the yeast, the product being 90% pure.
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    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
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    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: An account is given of the construction and operation of a fully automatic apparatus in which the material is kept under agitation in a closed container alternately surrounded by hot and cold alcohol supplied from separate baths. The apparatus has the following applications in microbiology and cell physiology: (1)Extraction of micro-organisms and cell tissues by repeated freezing (F) and thawing (T) at variable temperatures and lengths of FT cycle. Extraction can be controlled automatically or manually. As a practical example of the use of the apparatus a description is given of the extraction of living virulent S. typhi bacteria.(2)Studies of the reactions of living micro-organisms and tissues under varying physical conditions (e.g. high- and low-temperature resistance experiments, osmotic studies, thermal synchronization of bacterial cultures, etc.).(3)If required, the normal gas mixture in the residual air space can without difficulty be replaced by other gases or mixtures such as CO2 or N2.
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    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
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    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
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    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
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  • 39
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    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The design and construction of a highly sensitive katharometer is described with special reference to the application of the instrument for the precise determination of traces of ethylene by gas chromatography. Factors influencing katharometer sensitivity, and the relative advantages and disadvantages of katharometers as compared with other types of detectors, are discussed.
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    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: During the biosynthetic production of chlortetracycline on a medium with sucrose, soy meal, corn steep extract, sodium chloride, ammonium sulphate, calcium carbonate and beet molasses, the amount of nucleic acids synthesized by the culture and the maximum respiration of the culture is determined by the amount of inorganic phosphate in the original medium. Chlortetracycline production does not start until all the inorganic phosphate has been consumed. The adverse influence of increased amounts of inorganic phosphate upon production of chlortetracycline is more apparent in flasks on a shaking machine than in agitated and aerated fermentation tanks with higher oxygen transfer numbers.
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    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: An electrophoretic method for the separation of acid polyelectrolytes from proteins in cell extracts is described.A description of the apparatus is given and some results of the separation of extracts from Bordetella pertussis are included.
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    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: An ultrasonic generator was tested at 3 frequencies for its effects on Serratia marcescens during fermentation. The generator controlled foam adequately at 26, 29, and 34 kc/sec at medium aeration rates up to 0·6 ft3/min. Final viable counts were in the same range as those for cultures grown using lard oil as a foam control agent. At 34 kc/sec the final viable counts were slightly higher than those of cultures with lard oil.No harmful effects were evident when large volumes of cultures were exposed to ultrasonic energy during growth.
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    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A simple, rugged and compact automatic feed control attachment for the laboratory-size glass circulating evaporator has been designed and constructed. Experience has demonstrated that this apparatus operates satisfactorily with a variety of aqueous biological extracts and solutions having resistivity values of 50,000 ohm-in. or less. The device in adaptable to other evaporators and stills.
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    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A description of the cultivation of Rhodospirillum rubrum in 1,000 and 3,000 l. fermentors fitted with a special illumination device, and a discussion of the results.
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    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Novobiocin fermentations in 20 l. baffled fermentors were studied as a function of the size and speed of the dual four-bladed flat-blade turbines used. Power input and sulphite oxidation rate measurements were made. The courses of pH, sugar utilization, mycelial dry weight, carbon dioxide evolution and antibiotic titer were determined. Optimum antibiotic yields were achieved at a power input of 0·5 h.p./100 gal, equivalent to a sulphite oxidation rate of 110 mmoles O2/l.h, when the impeller diameters were 29 per cent or 39 per cent of the tank diameter. A power input of 0·75 h.p./100 gal, equivalent to a sulphite oxidation rate of 160 mmoles O2/l.h, was required for equivalent results with the impeller diameter 49 per cent of the tank diameter. Some explanations of the lack of equivalent results with the large impeller are discussed.
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    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
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    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Probability theory has been applied to the analysis of bacterial distribution within a fibrous air sterilization filter. For a long filter layer, to which the so-called ‘log-penetration’ law is no longer applicable, the probability theory is considered to be effective in interpreting the distribution data.The effects of the diameter, volume fraction and moisture content of the glass-fibre on the longitudinal distribution of bacterial cells, were studied. The distribution was estimated beyond the experimental data points. This estimation will be of use for predicting the ‘life’ of an air sterilization filter.
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    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The equations of Monod that describe the course of bacterial population growth and substrate concentration during continuous culturing are usually analysed with reference to steady-state conditions. These equations are analysed to give information on the course of bacterial population growth from inoculation to the achievement of a steady-state condition. For common values of certain parameters occurring in Monod's development, growth is well approximated by an exponential law (logarithmic phase) which depends on: (a) the maximum specific growth-rate constant for the organism and medium concerned, and (b) the constant dilution rate.
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    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A pilot plant unit for continuous cultivation of hyphaeforming micro-organisms, providing for a uniform flow velocity in fermentations on suspension media with a massive growth of mycelium, is described. For the maintenance of aseptic conditions, over-pressre of air is maintained in the whole equipment. This equipment has been used for studies of the continuous biosynthesis of streptomycin. A three-stage fermentation proved the most advantageous. The first stage serves for multiplication of the inoculum; the second and third for the formation of the antibiotic. The system was maintained for 300-400 h with yields amounting to 2,000-2,500 u. of streptomycin/ml without any signs of contamination or degeneration of the growing culture.
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    New York, NY [u.a.] : Wiley-Blackwell
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The effect of agitation on the rate of acid formation by the microaerophilic organism Lactobacillus delbrueckii was studied. Fermentations were conducted at constant temperature and pH, and with the continuous addition of a nutrilite source. The range of agitator speeds was from 85 to 720 rev/min.The acid formation rate was found to increase with increasing agitator speeds and decrease with decreasing speeds if corn-steep liquor was the nutrilite source. No effect of agitation was observed with yeast extract as the nutrilite source.The data from corn-steep liquor media were found to be consistent with a mass transfer mechanism, but did not warrant a conclusion as to the specific nature of the effect of agitation. It was concluded, however, that the effect of agitation on the acid formation rate was at most very small.
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    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The feasibility of producing antibiotics by single-stage continuous fermentation was explored by means of a specially designed pilot plant. Both the chloramphenicol and penicillin processes appeared adaptable to such an operation. At dilution rates of 1·0 and 0·5 volume changes per day respectively, yields of from ¼ to ½ of the maxima obtained in batch operation were maintained in the steady-state for more than 2 weeks.
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    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Kinetic data are needed to develop basic understanding of fermentation processes and to permit rational design of continuous fermentation processes.The kinetics of the fermentation of glucose to lactic acid have been studied at six constant pH levels between 4·5 and 6·0 by measuring the instantaneous rates of bacterial growth and of lactic acid formation throughout each fermentation.It was found that the instantaneous rate of acid formation dP/dt, could be related to the instantaneous rate of bacterial growth dN/dt, and to the bacterial density N, throughout a fermentation at a given pH, by the expression \documentclass{article}\pagestyle{empty}\begin{document}$\frac{{{\rm d}P}}{{{\rm d}t}} = \alpha \frac{{{\rm d}N}}{{{\rm d}t}} + \beta N$\end{document} where the constants α and β are determined by the pH of the fermentation.
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    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Information on fermentation process kinetics is potentially valuable for the improvement of batch process performance; it is essential for continuous process design. An empirical examination of rate patterns in various fermentations discloses three basic types: (1) ‘growth associated’ products arising directly from the energy metabolism of carbohydrates supplied, (2) indirect products of carbohydrate metabolism and (3) products apparently unrelated to carbohydrate oxidation. Effects of operating variables on the primary kinetic processes, growth, sugar utilization and antibiotic formation, in the penicillin process, illustrate the special nature of this type.
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    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Steady-state and transient equations are derived for continuous-flow fermentation processes. Analytical as well as graphical methods for predicting from batch data the performance of single- or multi-stage continuous fermentations are developed. The criteria for stability are also examined. Actual experimental measurements of continuous lactic acid fermentations conducted at controlled pH levels agree with the theory developed.
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