WILBERT — Wildauer Bücher+E-Medien Recherche-Tool

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A novel joint analysis framework improves identification of differentially expressed genes in cross disease transcriptomic analysis (2018)

Wenyi Qin and Hui Lu

BioMed Central

In: BioData Mining

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Publication Date: 2018-03-06

Description: Detecting differentially expressed (DE) genes between disease and normal control group is one of the most common analyses in genome-wide transcriptomic data. Since most studies don’t have a lot of samples, res...

Electronic ISSN: 1756-0381

Topics: Biology , Computer Science

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Identification of influential observations in high-dimensional cancer survival data through the rank product test (2018)

Eunice Carrasquinha, André Veríssimo, Marta B. Lopes and Susana Vinga

BioMed Central

In: BioData Mining

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Publication Date: 2018-03-06

Description: Survival analysis is a statistical technique widely used in many fields of science, in particular in the medical area, and which studies the time until an event of interest occurs. Outlier detection in this co...

Electronic ISSN: 1756-0381

Topics: Biology , Computer Science

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3

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Scalable non-negative matrix tri-factorization (2018)

Andrej Čopar, Marinka žitnik and Blaž Zupan

BioMed Central

In: BioData Mining

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Publication Date: 2018-03-06

Description: Matrix factorization is a well established pattern discovery tool that has seen numerous applications in biomedical data analytics, such as gene expression co-clustering, patient stratification, and gene-disea...

Electronic ISSN: 1756-0381

Topics: Biology , Computer Science

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4

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An automated pipeline for bouton, spine, and synapse detection of in vivo two-photon images (2018)

Qiwei Xie, Xi Chen, Hao Deng, Danqian Liu, Yingyu Sun, Xiaojuan Zhou, Yang Yang and Hua Han

BioMed Central

In: BioData Mining

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Publication Date: 2018-03-06

Description: In the nervous system, the neurons communicate through synapses. The size, morphology, and connectivity of these synapses are significant in determining the functional properties of the neural network. Therefo...

Electronic ISSN: 1756-0381

Topics: Biology , Computer Science

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5

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Grade III bone cement implantation syndrome in malignant lung cancer patient: a case report (2018)

Pawan Kumar Hamal, Puspa Raj Poudel and Janith Singh

BioMed Central

In: BMC Anesthesiology

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Publication Date: 2018-03-06

Description: Bone cement implantation syndrome is a known complication causing mortality during perioperative period particularly in patients with malignancy. With rise in aging population with malignancy in low income cou...

Electronic ISSN: 1471-2253

Topics: Medicine

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6

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Pre-anesthetic assessment with three core questions for the detection of obstructive sleep apnea in childhood: An observational study (2018)

Joerg Schnoor, Thilo Busch, Nazar Turemuratov and Andreas Merkenschlager

BioMed Central

In: BMC Anesthesiology

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Publication Date: 2018-03-06

Description: Children with obstructive sleep apnea are at high risk for perioperative airway obstruction. Many “at risk” children may remain unrecognized. The aim of this study is to find a clinically practicable test to i...

Electronic ISSN: 1471-2253

Topics: Medicine

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7

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Characterization of sulfhydryl oxidase from Aspergillus tubingensis (2018)

Outi Nivala, Greta Faccio, Mikko Arvas, Perttu Permi, Johanna Buchert, Kristiina Kruus and Maija-Liisa Mattinen

BioMed Central

In: BMC Biochemistry

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Publication Date: 2018-03-06

Description: Despite of the presence of sulfhydryl oxidases (SOXs) in the secretomes of industrially relevant organisms and their many potential applications, only few of these enzymes have been biochemically characterized...

Electronic ISSN: 1471-2091

Topics: Chemistry and Pharmacology

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IntLIM: integration using linear models of metabolomics and gene expression data (2018)

Jalal K. Siddiqui, Elizabeth Baskin, Mingrui Liu, Carmen Z. Cantemir-Stone, Bofei Zhang, Russell Bonneville, Joseph P. McElroy, Kevin R. Coombes and Ewy A. Mathé

BioMed Central

In: BMC Bioinformatics

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Publication Date: 2018-03-06

Description: Integration of transcriptomic and metabolomic data improves functional interpretation of disease-related metabolomic phenotypes, and facilitates discovery of putative metabolite biomarkers and gene targets. Fo...

Electronic ISSN: 1471-2105

Topics: Biology , Computer Science

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9

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Natural language processing in text mining for structural modeling of protein complexes (2018)

Varsha D. Badal, Petras J. Kundrotas and Ilya A. Vakser

BioMed Central

In: BMC Bioinformatics

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Publication Date: 2018-03-06

Description: Structural modeling of protein-protein interactions produces a large number of putative configurations of the protein complexes. Identification of the near-native models among them is a serious challenge. Publ...

Electronic ISSN: 1471-2105

Topics: Biology , Computer Science

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Factors driving metabolic diversity in the budding yeast subphylum (2018)

Dana A. Opulente, Emily J. Rollinson, Cleome Bernick-Roehr, Amanda Beth Hulfachor, Antonis Rokas, Cletus P. Kurtzman and Chris Todd Hittinger

BioMed Central

In: BMC Biology

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Publication Date: 2018-03-06

Description: Associations between traits are prevalent in nature, occurring across a diverse range of taxa and traits. Individual traits may co-evolve with one other, and these correlations can be driven by factors intrins...

Electronic ISSN: 1741-7007

Topics: Biology

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11

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Measuring behavior across scales (2018)

Gordon J. Berman

BioMed Central

In: BMC Biology

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Publication Date: 2018-03-06

Description: The need for high-throughput, precise, and meaningful methods for measuring behavior has been amplified by our recent successes in measuring and manipulating neural circuitry. The largest challenges associated...

Electronic ISSN: 1741-7007

Topics: Biology

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GPMVs in variable physiological conditions: could they be used for therapy delivery? (2018)

Špela Zemljič Jokhadar, Urška Klančnik, Maja Grundner, Tjaša Švelc Kebe, Saša Vrhovec Hartman, Mirjana Liović and Jure Derganc

BioMed Central

In: BMC Biophysics

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Publication Date: 2018-03-06

Description: Cell based carriers are increasingly recognized as a good system for cargo delivery to cells. One of the reasons is their biocompatibility and low toxicity compared to artificial systems. Giant plasma membrane...

Electronic ISSN: 2046-1682

Topics: Biology , Physics

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13

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Agrobacterium-mediated and electroporation-mediated transformation of Chlamydomonas reinhardtii: a comparative study (2018)

Paola Mini, Olivia Costantina Demurtas, Silvia Valentini, Patrizia Pallara, Giuseppe Aprea, Paola Ferrante and Giovanni Giuliano

BioMed Central

In: BMC Biotechnology

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Publication Date: 2018-03-06

Description: Chlamydomonas reinhardtii is an unicellular green alga used for functional genomics studies and heterologous protein expression. A major hindrance in these studies is the low level and instability of expression o...

Electronic ISSN: 1472-6750

Topics: Process Engineering, Biotechnology, Nutrition Technology

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A new approach for detecting adventitious viruses shows Sf-rhabdovirus-negative Sf-RVN cells are suitable for safe biologicals production (2018)

Christoph Geisler

BioMed Central

In: BMC Biotechnology

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Publication Date: 2018-03-06

Description: Adventitious viral contamination in cell substrates used for biologicals production is a major safety concern. A powerful new approach that can be used to identify adventitious viruses is a combination of bioi...

Electronic ISSN: 1472-6750

Topics: Process Engineering, Biotechnology, Nutrition Technology

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Mixed response on regorafenib treatment for GIST (gastro-intestinal stromal tumor) according to 18F–FDG-PET/CT (2018)

Donatienne Van Weehaeghe, Olivier Gheysens, Vincent Vandecaveye, Patrick Schöffski, Koen Van Laere and Christophe M. Deroose

BioMed Central

In: BMC Cancer

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Publication Date: 2018-03-06

Description: Gastro-intestinal stromal tumors (GISTs) are very rare tumors of the gastro-intestinal tract, originating from the interstitial cells of Cajal or a common cell precursor which both express type III tyrosine ki...

Electronic ISSN: 1471-2407

Topics: Medicine

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A population-based analysis of germline BRCA1 and BRCA2 testing among ovarian cancer patients in an era of histotype-specific approaches to ovarian cancer prevention (2018)

Gillian E. Hanley, Jessica N. McAlpine, Dianne Miller, David Huntsman, Kasmintan A. Schrader, C. Blake Gilks and Gillian Mitchell

BioMed Central

In: BMC Cancer

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Publication Date: 2018-03-06

Description: Identifying female carriers of BRCA1 and BRCA2 mutations is imperative for prevention of ovarian cancer and breast cancer. There are five major histologic subtypes of ovarian cancer and high grade serous cancer (...

Electronic ISSN: 1471-2407

Topics: Medicine

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Percutaneous closure versus medical therapy for stroke with patent foramen Ovale: a systematic review and meta-analysis (2018)

Xin-Lin Zhang, Li-Na Kang, Lian Wang and Biao Xu

BioMed Central

In: BMC Cardiovascular Disorders

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Publication Date: 2018-03-06

Description: Patent foramen ovale (PFO) closure has emerged as a secondary prevention option in patients with PFO and cryptogenic stroke. However, the comparative efficacy and safety of percutaneous closure and medical the...

Electronic ISSN: 1471-2261

Topics: Medicine

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MicroRNA-17-5p aggravates lipopolysaccharide-induced injury in nasal epithelial cells by targeting Smad7 (2018)

Nan Huang, Wenjing Li, Xiaolong Wang and Shanshan Qi

BioMed Central

In: BMC Cell Biology

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Publication Date: 2018-03-06

Description: Globally, rhinitis is one of the most common chronic disorders. Despite availability of drugs to manage the symptomatology of rhinitis, researchers still focus on identification of novel molecular targets for ...

Electronic ISSN: 1471-2121

Topics: Biology , Medicine

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19

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A novel interaction between kinase activities in regulation of cilia formation (2018)

Nicole De; Vaul, Katerina Koloustroubis, Rong Wang and Ann O. Sperry

BioMed Central

In: BMC Cell Biology

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Publication Date: 2018-03-06

Description: The primary cilium is an extension of the cell membrane that encloses a microtubule-based axoneme. Primary cilia are essential for transmission of environmental cues that determine cell fate. Disruption of pri...

Electronic ISSN: 1471-2121

Topics: Biology , Medicine

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20

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Primary hepatic neuroendocrine carcinoma: report of two cases and literature review (2018)

Zi-Ming Zhao, Jin Wang, Ugochukwu C. Ugwuowo, Liming Wang and Jeffrey P. Townsend

BioMed Central

In: BMC Clinical Pathology

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Publication Date: 2018-03-06

Description: Primary hepatic neuroendocrine carcinoma (PHNEC) is extremely rare. The diagnosis of PHNEC remains challenging—partly due to its rarity, and partly due to its lack of unique clinical features. Available treatm...

Electronic ISSN: 1472-6890

Topics: Medicine

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Monocarboxylate Transporter 1 (MCT1) is an independent prognostic biomarker in endometrial cancer (2018)

Ayşe Latif, Amy L. Chadwick, Sarah J. Kitson, Hannah J. Gregson, Vanitha N. Sivalingam, James Bolton, Rhona J. McVey, Stephen A. Roberts, Kay M. Marshall, Kaye J. Williams, Ian J. Stratford and Emma J. Crosbie

BioMed Central

In: BMC Clinical Pathology

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Publication Date: 2018-03-06

Description: Endometrial cancer (EC) is a major health concern due to its rising incidence. Whilst early stage disease is generally cured by surgery, advanced EC has a poor prognosis with limited treatment options. Altered...

Electronic ISSN: 1472-6890

Topics: Medicine

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22

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Glycyl-alanyl-histidine protects PC12 cells against hydrogen peroxide toxicity (2018)

Hideki Shimura, Ryota Tanaka, Yoshiaki Shimada, Kazuo Yamashiro, Nobutaka Hattori and Takao Urabe

BioMed Central

In: BMC Biochemistry

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Publication Date: 2018-03-06

Description: Peptides with cytoprotective functions, including antioxidants and anti-infectives, could be useful therapeutics. Carnosine, β-alanine-histidine, is a dipeptide with anti-oxidant properties. Tripeptides of Ala...

Electronic ISSN: 1471-2091

Topics: Chemistry and Pharmacology

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23

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Characterization and visualization of RNA secondary structure Boltzmann ensemble via information theory (2018)

Luan Lin, Wilson H. McKerrow, Bryce Richards, Chukiat Phonsom and Charles E. Lawrence

BioMed Central

In: BMC Bioinformatics

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Publication Date: 2018-03-06

Description: The nearest neighbor model and associated dynamic programming algorithms allow for the efficient estimation of the RNA secondary structure Boltzmann ensemble. However because a given RNA secondary structure on...

Electronic ISSN: 1471-2105

Topics: Biology , Computer Science

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24

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ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models (2018)

Skylar W. Marvel, Kimberly To, Fabian A. Grimm, Fred A. Wright, Ivan Rusyn and David M. Reif

BioMed Central

In: BMC Bioinformatics

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Publication Date: 2018-03-06

Description: Drawing integrated conclusions from diverse source data requires synthesis across multiple types of information. The ToxPi (Toxicological Prioritization Index) is an analytical framework that was developed to ...

Electronic ISSN: 1471-2105

Topics: Biology , Computer Science

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25

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Cross-communication between Gi and Gs in a G-protein-coupled receptor heterotetramer guided by a receptor C-terminal domain (2018)

Gemma Navarro, Arnau Cordomí, Marc Brugarolas, Estefanía Moreno, David Aguinaga, Laura Pérez-Benito, Sergi Ferre, Antoni Cortés, Vicent Casadó, Josefa Mallol, Enric I. Canela, Carme Lluís, Leonardo Pardo, Peter J. McCormick and Rafael Franco

BioMed Central

In: BMC Biology

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Publication Date: 2018-03-06

Description: G-protein-coupled receptor (GPCR) heteromeric complexes have distinct properties from homomeric GPCRs, giving rise to new receptor functionalities. Adenosine receptors (A1R or A2AR) can form A1R-A2AR heteromers (...

Electronic ISSN: 1741-7007

Topics: Biology

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26

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Synaptic neuron-astrocyte communication is supported by an order of magnitude analysis of inositol tris-phosphate diffusion at the nanoscale in a model of peri-synaptic astrocyte projection (2018)

Pavel Montes de Oca Balderas and Horacio Montes de Oca Balderas

BioMed Central

In: BMC Biophysics

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Publication Date: 2018-03-06

Description: Astrocytes were conceived for decades only as supporting cells of the brain. However, the observation of Ca2+ waves in astrocyte synctitia, their neurotransmitter receptor expression and gliotransmitter secret...

Electronic ISSN: 2046-1682

Topics: Biology , Physics

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27

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Human S100A5 binds Ca2+ and Cu2+ independently (2018)

Lucas C. Wheeler and Michael J. Harms

BioMed Central

In: BMC Biophysics

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Publication Date: 2018-03-06

Description: S100A5 is a calcium binding protein found in a small subset of amniote tissues. Little is known about the biological roles of S100A5, but it may be involved in inflammation and olfactory signaling. Previous wo...

Electronic ISSN: 2046-1682

Topics: Biology , Physics

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28

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Genetically encoded calcium indicator with NTnC-like design and enhanced fluorescence contrast and kinetics (2018)

D. A. Doronin, N. V. Barykina, O. M. Subach, V. P. Sotskov, V. V. Plusnin, O. A. Ivleva, E. A. Isaakova, A. M. Varizhuk, G. E. Pozmogova, A. Y. Malyshev, I. V. Smirnov, K. D. Piatkevich, K. V. Anokhin, G. N. Enikolopov and F. V. Subach

BioMed Central

In: BMC Biotechnology

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Publication Date: 2018-03-06

Description: The recently developed genetically encoded calcium indicator (GECI), called NTnC, has a novel design with reduced size due to utilization of the troponin C (TnC) as a Ca2+-binding moiety inserted into the mNeonGr...

Electronic ISSN: 1472-6750

Topics: Process Engineering, Biotechnology, Nutrition Technology

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29

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DNA methylome profiling at single-base resolution through bisulfite sequencing of 5mC-immunoprecipitated DNA (2018)

Zhen Jia, Yueyi Shi, Lei Zhang, Yipeng Ren, Tong Wang, Lejun Xing, Baorong Zhang, Guolan Gao and Rongfa Bu

BioMed Central

In: BMC Biotechnology

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Publication Date: 2018-03-06

Description: Detection of DNA methylome at single-base resolution is a significant challenge but promises to shed considerable light on human disease etiology. Current technologies could not detect DNA methylation genome-w...

Electronic ISSN: 1472-6750

Topics: Process Engineering, Biotechnology, Nutrition Technology

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30

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Targeted next generation sequencing identified clinically actionable mutations in patients with esophageal sarcomatoid carcinoma (2018)

Hongyang Lu, Shifeng Yang, Huineng Zhu, Xiaoling Tong, Fajun Xie, Jing Qin, Na Han, Xue Wu, Yun Fan, Yang W. Shao and Weimin Mao

BioMed Central

In: BMC Cancer

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Publication Date: 2018-03-06

Description: Esophageal sarcomatoid carcinoma (ESC) is a rare disease with a mixture of both carcinomatous and sarcomatous components in the tumor. Its genetic background and mechanisms of oncogenesis remain largely unknown.

Electronic ISSN: 1471-2407

Topics: Medicine

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31

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A case of anterior spinal cord syndrome in a patient with unruptured thoracic aortic aneurysm with a mural thrombus (2018)

Nilukshana Yogendranathan, H. M. M. T. B. Herath, W. D. Jayamali, Anne Thushara Matthias, Aruna Pallewatte and Aruna Kulatunga

BioMed Central

In: BMC Cardiovascular Disorders

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Publication Date: 2018-03-06

Description: Spinal cord infarction is an uncommon condition. Anterior cord syndrome present with paraparesis or quadriparesis with sparing of vibration and proprioceptive senses. The common causes of anterior cord syndrom...

Electronic ISSN: 1471-2261

Topics: Medicine

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The expression of MDM2 in gastrointestinal stromal tumors: immunohistochemical analysis of 35 cases (2018)

Boubacar Efared, Gabrielle Atsame-Ebang, Layla Tahiri, Ibrahim Sory Sidibé, Fatimazahra Erregad, Nawal Hammas, Samia Arifi, Ihsane Mellouki, Abdelmalek Ousadden, Khalid Mazaz, Hinde El Fatemi and Laila Chbani

BioMed Central

In: BMC Clinical Pathology

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Publication Date: 2018-03-06

Description: Gastrointestinal stromal tumors (GIST) are the most common primary mesenchymal tumors of the digestive system. The assessment of their biological behavior still remains a scientific challenge. To date, there a...

Electronic ISSN: 1472-6890

Topics: Medicine

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Rhaponticum acaule (L) DC essential oil: chemical composition, in vitro antioxidant and enzyme inhibition properties (2018)

Habib Mosbah, Hassiba Chahdoura, Jannet Kammoun, Malek Besbes Hlila, Hanen Louati, Saoussen Hammami, Guido Flamini, Lotfi Achour and Boulbaba Selmi

BioMed Central

In: BMC Complementary and Alternative Medicine

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Publication Date: 2018-03-06

Description: α-glucosidase is a therapeutic target for diabetes mellitus (DM) and α-glucosidase inhibitors play a vital role in the treatments for the disease. Furthermore, xanthine oxidase (XO) is a key enzyme that cataly...

Electronic ISSN: 1472-6882

Topics: Medicine

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34

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Immune-enhancing activity of C. militaris fermented with Pediococcus pentosaceus (GRC-ON89A) in CY-induced immunosuppressed model (2018)

Ha-Kyoung Kwon, Woo-Ri Jo and Hye-Jin Park

BioMed Central

In: BMC Complementary and Alternative Medicine

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Publication Date: 2018-03-06

Description: Cordyceps militaris (C. militaris) is reported to exert various immune-activities. To enhance its activity, we fermented C.militaris with Pediococcus pentosaceus ON89A (GRC-ON89A). In this study, we investigated ...

Electronic ISSN: 1472-6882

Topics: Medicine

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35

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Elucidating mechanistic insights into drug action for atopic dermatitis: a systems biology approach (2018)

Indhupriya Subramanian, Vivek K. Singh and Abhay Jere

BioMed Central

In: BMC Dermatology

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Publication Date: 2018-03-06

Description: Topical Betamethasone (BM) and Pimecrolimus (PC) are widely used drugs in the treatment of atopic dermatitis (AD). Though the biomolecules and biological pathways affected by the drugs are known, the causal in...

Electronic ISSN: 1471-5945

Topics: Medicine

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Composite hemangioendothelioma of the forehead and right eye; a case report (2018)

Ghasem Rahmatpour Rokni, Fatemeh Montazer, Mahnaz Sharifian and Mohamad Goldust

BioMed Central

In: BMC Dermatology

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Publication Date: 2018-03-06

Description: Hemangioendothelioma includes several types of vascular neoplasms, as well as both benign and malignant growth.

Electronic ISSN: 1471-5945

Topics: Medicine

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Expression and function of microRNA-9 in the mid-hindbrain area of embryonic chick (2018)

A. Alwin Prem Anand, Carola Huber, John Asnet Mary, Nancy Gallus, Christoph Leucht, Ruth Klafke, Bernhard Hirt and Andrea Wizenmann

BioMed Central

In: BMC Developmental Biology

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Publication Date: 2018-03-06

Description: MiR-9 is a small non-coding RNA that is highly conserved between species and primarily expressed in the central nervous system (CNS). It is known to influence proliferation and neuronal differentiation in the ...

Electronic ISSN: 1471-213X

Topics: Biology , Medicine

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38

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The role of tonsillectomy in the Periodic Fever, Aphthous stomatitis, Pharyngitis and cervical Adenitis syndrome; a literature review (2018)

Jostein Førsvoll and Knut Øymar

BioMed Central

In: BMC Ear, Nose and Throat Disorders

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Publication Date: 2018-03-06

Description: Tonsillectomy (TE) or adenotonsillectomy (ATE) may have a beneficial effect on the clinical course in children with the Periodic Fever, Aphthous stomatitis, Pharyngitis and cervical Adenitis (PFAPA) syndrome. ...

Electronic ISSN: 1472-6815

Topics: Medicine

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39

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Causes of higher symptomatic airway load in patients with chronic rhinosinusitis (2018)

Øystein Eskeland, Kjell Arild Danielsen, Fredrik Dahl, Katrin Fridrich, Vivian Cecilie Orszagh, Gregor Bachmann-Harildstad and Espen Burum-Auensen

BioMed Central

In: BMC Ear, Nose and Throat Disorders

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Publication Date: 2018-03-06

Description: Chronic rhinosinusitis display a variety of different phenotypes. The symptoms of disease are characterised by various signs and symptoms such as nasal congestion, nasal discharge, pressure sensation in the fa...

Electronic ISSN: 1472-6815

Topics: Medicine

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40

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Ambulance use is not associated with patient acuity after road traffic collisions: a cross-sectional study from Addis Ababa, Ethiopia (2018)

Yonas Abebe, Tolesa Dida, Engida Yisma and David M. Silvestri

BioMed Central

In: BMC Emergency Medicine

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Publication Date: 2018-03-06

Description: Africa accounts for one sixth of global road traffic deaths—most in the pre-hospital setting. Ambulance transport is expensive relative to other modes of pre-hospital transport, but has advantages in time-sens...

Electronic ISSN: 1471-227X

Topics: Medicine

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41

Unknown

Systematic reporting to improve the emergency medical response to major incidents: a pilot study (2018)

Sophie Hardy, Sabina Fattah, Torben Wisborg, Lasse Raatiniemi, Trine Staff and Marius Rehn

BioMed Central

In: BMC Emergency Medicine

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Publication Date: 2018-03-06

Description: Major incidents affect us globally, and are occurring with increasing frequency. There is still no evidence-based standard regarding the best medical emergency response to major incidents. Currently, reports o...

Electronic ISSN: 1471-227X

Topics: Medicine

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42

Unknown

A searchable database of medical education objectives – creating a comparable gold standard (2018)

Sam Brooks, Namita Biala and Sage Arbor

BioMed Central

In: BMC Medical Education

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Publication Date: 2018-03-06

Description: Medical school curricula strives to teach as much material as can be retained in a limited amount of time. A common “gold standard” resource used building curricula are medical objectives suggested by national...

Electronic ISSN: 1472-6920

Topics: Medicine , Education

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43

Unknown

Correction to: An audit of clinical training exposure amongst junior doctors working in Trauma & Orthopaedic Surgery in 101 hospitals in the United Kingdom (2018)

Mustafa S. Rashid

BioMed Central

In: BMC Medical Education

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Publication Date: 2018-03-06

Description: Following publication of the original article [1], the corresponding author wrote to say that he had missed the names of some of the collaborators in the list he sent to the typesetters. In addition, there was...

Electronic ISSN: 1472-6920

Topics: Medicine , Education

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44

Unknown

Screening for infectious diseases of asylum seekers upon arrival: the necessity of the moral principle of reciprocity (2018)

Dorien T. Beeres, Darren Cornish, Machiel Vonk, Sofanne J. Ravensbergen, Els L. M. Maeckelberghe, Pieter Boele Van Hensbroek and Ymkje Stienstra

BioMed Central

In: BMC Medical Ethics

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Publication Date: 2018-03-06

Description: With a large number of forcibly displaced people seeking safety, the EU is facing a challenge in maintaining solidarity. Europe has seen millions of asylum seekers crossing European borders, the largest number...

Electronic ISSN: 1472-6939

Topics: Medicine , Philosophy

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45

Unknown

A case of an infant suspected as IMAGE syndrome who were finally diagnosed with MIRAGE syndrome by targeted Mendelian exome sequencing (2018)

Yoon-Myung Kim, Go Hun Seo, Gu-Hwan Kim, Jung Min Ko, Jin-Ho Choi and Han-Wook Yoo

BioMed Central

In: BMC Medical Genetics

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Publication Date: 2018-03-06

Description: Adrenal hypoplasia is a rare congenital disorder, which can be classified into a non-syndromic form, without extra-adrenal features, and a syndromic form, with such features. Despite biochemical and molecular ...

Electronic ISSN: 1471-2350

Topics: Biology , Medicine

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46

Unknown

What to consider when pseudohypoparathyroidism is ruled out: iPPSD and differential diagnosis (2018)

Arrate Pereda, Intza Garin and Guiomar Perez de Nanclares

BioMed Central

In: BMC Medical Genetics

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Publication Date: 2018-03-06

Description: Pseudohypoparathyroidism (PHP) is a rare disease whose phenotypic features are rather difficult to identify in some cases. Thus, although these patients may present with the Albright’s hereditary osteodystroph...

Electronic ISSN: 1471-2350

Topics: Biology , Medicine

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47

Unknown

Impaired type I interferon regulation in the blood transcriptome of recurrent asthma exacerbations (2018)

Jose L. Gomez, Maria P. Diaz, Gustavo Nino and Clemente J. Britto

BioMed Central

In: BMC Medical Genomics

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Publication Date: 2018-03-06

Description: Asthma exacerbations are an important cause of morbidity in asthma. Respiratory infections are often involved in asthma exacerbations in both children and adults. Some individuals with asthma have increased su...

Electronic ISSN: 1755-8794

Topics: Medicine

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48

Unknown

Primary microcephaly case from the Karachay-Cherkess Republic poses an additional support for microcephaly and Seckel syndrome spectrum disorders (2018)

Andrey V. Marakhonov, Fedor A. Konovalov, Amin Kh. Makaov, Tatyana A. Vasilyeva, Vitaly V. Kadyshev, Varvara A. Galkina, Elena L. Dadali, Sergey I. Kutsev and Rena A. Zinchenko

BioMed Central

In: BMC Medical Genomics

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Publication Date: 2018-03-06

Description: Primary microcephaly represents an example of clinically and genetically heterogeneous condition. Here we describe a case of primary microcephaly from the Karachay-Cherkess Republic, which was initially diagno...

Electronic ISSN: 1755-8794

Topics: Medicine

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49

Unknown

Systemic air embolism after percutaneous computed tomography-guided lung biopsy due to a kink in the coaxial biopsy system: a case report (2018)

Hsu-Chao Chang and Mei-Chen Yang

BioMed Central

In: BMC Medical Imaging

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Publication Date: 2018-03-06

Description: Systemic air embolism is a rare but potentially life-threatening complication of percutaneous computed tomography (CT)-guided lung biopsy. The incidence might be underestimated because of failure to diagnose t...

Electronic ISSN: 1471-2342

Topics: Biology

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50

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Effective behavioral intervention strategies using mobile health applications for chronic disease management: a systematic review (2018)

Jung-Ah Lee, Mona Choi, Sang A Lee and Natalie Jiang

BioMed Central

In: BMC Medical Informatics and Decision Making

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Publication Date: 2018-03-06

Description: Mobile health (mHealth) has continuously been used as a method in behavioral research to improve self-management in patients with chronic diseases. However, the evidence of its effectiveness in chronic disease...

Electronic ISSN: 1472-6947

Topics: Computer Science , Medicine

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51

Unknown

Combining information from a clinical data warehouse and a pharmaceutical database to generate a framework to detect comorbidities in electronic health records (2018)

Emmanuelle Sylvestre, Guillaume Bouzillé, Emmanuel Chazard, Cécil His-Mahier, Christine Riou and Marc Cuggia

BioMed Central

In: BMC Medical Informatics and Decision Making

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Publication Date: 2018-03-06

Description: Medical coding is used for a variety of activities, from observational studies to hospital billing. However, comorbidities tend to be under-reported by medical coders. The aim of this study was to develop an a...

Electronic ISSN: 1472-6947

Topics: Computer Science , Medicine

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52

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Advantages of a multi-state approach in surgical research: how intermediate events and risk factor profile affect the prognosis of a patient with locally advanced rectal cancer (2018)

G. Manzini, T. J. Ettrich, M. Kremer, M. Kornmann, D. Henne-Bruns, D. A. Eikema, P. Schlattmann and L. C. de Wreede

BioMed Central

In: BMC Medical Research Methodology

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Publication Date: 2018-03-06

Description: Standard survival analysis fails to give insight into what happens to a patient after a first outcome event (like first relapse of a disease). Multi-state models are a useful tool for analyzing survival data w...

Electronic ISSN: 1471-2288

Topics: Medicine

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53

Unknown

Value of information methods to design a clinical trial in a small population to optimise a health economic utility function (2018)

Michael Pearce, Siew Wan Hee, Jason Madan, Martin Posch, Simon Day, Frank Miller, Sarah Zohar and Nigel Stallard

BioMed Central

In: BMC Medical Research Methodology

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Publication Date: 2018-03-06

Description: Most confirmatory randomised controlled clinical trials (RCTs) are designed with specified power, usually 80% or 90%, for a hypothesis test conducted at a given significance level, usually 2.5% for a one-sided...

Electronic ISSN: 1471-2288

Topics: Medicine

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54

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Adaptive designs in clinical trials: why use them, and how to run and report them (2018)

Philip Pallmann, Alun W. Bedding, Babak Choodari-Oskooei, Munyaradzi Dimairo, Laura Flight, Lisa V. Hampson, Jane Holmes, Adrian P. Mander, Lang’o Odondi, Matthew R. Sydes, Sofía S. Villar, James M. S. Wason, Christopher J. Weir, Graham M. Wheeler, Christina Yap and Thomas Jaki

BioMed Central

In: BMC Medicine

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Publication Date: 2018-03-06

Description: Adaptive designs can make clinical trials more flexible by utilising results accumulating in the trial to modify the trial’s course in accordance with pre-specified rules. Trials with an adaptive design are of...

Electronic ISSN: 1741-7015

Topics: Medicine

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55

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Complete genomic sequences of Propionibacterium freudenreichii phages from Swiss cheese reveal greater diversity than Cutibacterium (formerly Propionibacterium) acnes phages (2018)

Lucy Cheng, Laura J. Marinelli, Noël Grosset, Sorel T. Fitz-Gibbon, Charles A. Bowman, Brian Q. Dang, Daniel A. Russell, Deborah Jacobs-Sera, Baochen Shi, Matteo Pellegrini, Jeff F. Miller, Michel Gautier, Graham F. Hatfull and Robert L. Modlin

BioMed Central

In: BMC Microbiology

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Publication Date: 2018-03-06

Description: A remarkable exception to the large genetic diversity often observed for bacteriophages infecting a specific bacterial host was found for the Cutibacterium acnes (formerly Propionibacterium acnes) phages, which a...

Electronic ISSN: 1471-2180

Topics: Biology

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56

Unknown

Involvement of polymorphisms of the nerve growth factor and its receptor encoding genes in the etiopathogenesis of ischemic stroke (2018)

Ani Stepanyan, Roksana Zakharyan, Arsen Simonyan, Gohar Tsakanova and Arsen Arakelyan

BioMed Central

In: BMC Medical Genetics

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Publication Date: 2018-03-06

Description: Despite the important role of the nerve growth factor in the survival and maintenance of neurons in ischemic stroke, data regarding the relationships between variations in the encoding gene and stroke are lack...

Electronic ISSN: 1471-2350

Topics: Biology , Medicine

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57

Unknown

An optimized rapid bisulfite conversion method with high recovery of cell-free DNA (2018)

Shaohua Yi, Fei Long, Juanbo Cheng and Daixin Huang

BioMed Central

In: BMC Molecular Biology

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Publication Date: 2018-03-06

Description: Methylation analysis of cell-free DNA is a encouraging tool for tumor diagnosis, monitoring and prognosis. Sensitivity of methylation analysis is a very important matter due to the tiny amounts of cell-free DN...

Electronic ISSN: 1471-2199

Topics: Biology

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58

Unknown

Physical shearing imparts biological activity to DNA and ability to transmit itself horizontally across species and kingdom boundaries (2018)

Gorantla Venkata Raghuram, Deepika Gupta, Siddharth Subramaniam, Ashwini Gaikwad, Naveen Kumar Khare, Malcolm Nobre, Naveen Kumar Nair and Indraneel Mittra

BioMed Central

In: BMC Molecular Biology

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Publication Date: 2018-03-06

Description: We have recently reported that cell-free DNA (cfDNA) fragments derived from dying cells that circulate in blood are biologically active molecules and can readily enter into healthy cells to activate DNA damage...

Electronic ISSN: 1471-2199

Topics: Biology

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59

Unknown

A case of bilateral revision total knee arthroplasty using distal femoral allograft–prosthesis composite and femoral head allografting at the tibial site with a varus-valgus constrained prosthesis: ten-year follow up (2018)

Sung-Hyun Lee, Sung-Hyun Noh, Keun-Churl Chun, Joung-Kyue Han and Churl-Hong Chun

BioMed Central

In: BMC Musculoskeletal Disorders

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Publication Date: 2018-03-06

Description: We report the successful use of allograft–prosthesis composite (APC) and structural femoral head allografting in the bilateral reconstruction of large femoral and tibial uncontained defects during revision tot...

Electronic ISSN: 1471-2474

Topics: Medicine

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60

Unknown

The association between soluble klotho and cardiovascular parameters in chronic kidney disease: results from the KNOW-CKD study (2018)

Hyo Jin Kim, Eunjeong Kang, Yun Kyu Oh, Yeong Hoon Kim, Seung Hyeok Han, Tae Hyun Yoo, Dong-Wan Chae, Joongyub Lee, Curie Ahn and Kook-Hwan Oh

BioMed Central

In: BMC Nephrology

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Publication Date: 2018-03-06

Description: Klotho, a protein linked to aging, has emerged as a pivotal player in mineral bone metabolism and might explain the relationship between chronic kidney disease (CKD) and cardiovascular disease (CVD). The prese...

Electronic ISSN: 1471-2369

Topics: Medicine

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61

Unknown

Quality of life in hemodialysis diabetic patients: a multicenter cross-sectional study from Palestine (2018)

Sohaib T. Khatib, Mohammad K. Hemadneh, Samer A. Hasan, Emad Khazneh and Sa’ed H. Zyoud

BioMed Central

In: BMC Nephrology

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Publication Date: 2018-03-06

Description: Both diabetes and hemodialysis can seriously impair patients’ health related quality of life (HRQOL). This study seeks to obtain data which will help to address the factors associated with impaired HRQOL in he...

Electronic ISSN: 1471-2369

Topics: Medicine

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62

Unknown

Risk variants of the α-synuclein locus and REM sleep behavior disorder in Parkinson’s disease: a genetic association study (2018)

Kari Anne Bjørnarå, Lasse Pihlstrøm, Espen Dietrichs and Mathias Toft

BioMed Central

In: BMC Neurology

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Publication Date: 2018-03-06

Description: Parkinson’s disease is a heterogeneous disorder where genetic factors may underlie clinical variability. Rapid eye movement sleep behavior disorder (RBD) is a parasomnia strongly linked to synucleinopathies, i...

Electronic ISSN: 1471-2377

Topics: Medicine

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63

Unknown

Effect of tendon vibration during wide-pulse neuromuscular electrical stimulation (NMES) on muscle force production in people with spinal cord injury (SCI) (2018)

Vanesa Bochkezanian, Robert U. Newton, Gabriel S. Trajano, Amilton Vieira, Timothy S. Pulverenti and Anthony J. Blazevich

BioMed Central

In: BMC Neurology

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Publication Date: 2018-03-06

Description: Neuromuscular electrical stimulation (NMES) is commonly used in skeletal muscles in people with spinal cord injury (SCI) with the aim of increasing muscle recruitment and thus muscle force production. NMES has...

Electronic ISSN: 1471-2377

Topics: Medicine

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64

Unknown

Modelling physiological and pathological conditions to study pericyte biology in brain function and dysfunction (2018)

Justin Rustenhoven, Leon C. Smyth, Deidre Jansson, Patrick Schweder, Miranda Aalderink, Emma L. Scotter, Edward W. Mee, Richard L. M. Faull, Thomas I.-H. Park and Mike Dragunow

BioMed Central

In: BMC Neuroscience

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Publication Date: 2018-03-06

Description: Brain pericytes ensheathe the endothelium and contribute to formation and maintenance of the blood–brain-barrier. Additionally, pericytes are involved in several aspects of the CNS immune response including sc...

Electronic ISSN: 1471-2202

Topics: Medicine

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65

Unknown

From apprehension to advocacy: a qualitative study of undergraduate nursing student experience in clinical placement in residential aged care (2018)

Heather Moquin, Cydnee Seneviratne and Lorraine Venturato

BioMed Central

In: BMC Nursing

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Publication Date: 2018-03-06

Description: Undergraduate nursing placement in aged care is forecast to grow in importance with the increasing aging population, and to help to reverse trends in student lack of interest in gerontology careers. However, t...

Electronic ISSN: 1472-6955

Topics: Medicine

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66

Unknown

Predictors of activity and participation across neurodegenerative conditions: a comparison of people with motor neurone disease, multiple sclerosis and Parkinson’s disease (2018)

David Morley, Sarah Dummett, Laura Kelly, Ray Fitzpatrick and Crispin Jenkinson

BioMed Central

In: BMC Neurology

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Publication Date: 2018-03-06

Description: Comparisons between neurological conditions have the potential to inform service providers by identifying particular areas of difficulty experienced by affected individuals. This study aimed to identify predic...

Electronic ISSN: 1471-2377

Topics: Medicine

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67

Unknown

Metabolomics analysis of serum in a rat heroin self-administration model undergoing reinforcement based on 1H-nuclear magnetic resonance spectra (2018)

Tingting Ning, Changlong Leng, Lin Chen, Baomiao Ma and Xiaokang Gong

BioMed Central

In: BMC Neuroscience

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Publication Date: 2018-03-06

Description: Understanding the process of relapse to abused drugs and ultimately developing treatments that can reduce the incidence of relapse remains the primary goal for the study of substance dependence. Therefore, exp...

Electronic ISSN: 1471-2202

Topics: Medicine

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68

Unknown

Characterisation of Zika virus infection in primary human astrocytes (2018)

Michal Stefanik, Petra Formanova, Tomas Bily, Marie Vancova, Ludek Eyer, Martin Palus, Jiri Salat, Carla Torres Braconi, Paolo M. de A. Zanotto, Ernest A. Gould and Daniel Ruzek

BioMed Central

In: BMC Neuroscience

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Publication Date: 2018-03-06

Description: The recent Zika virus (ZIKV) outbreak has linked ZIKV with microcephaly and other central nervous system pathologies in humans. Astrocytes are among the first cells to respond to ZIKV infection in the brain an...

Electronic ISSN: 1471-2202

Topics: Medicine

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69

Unknown

Lessons learnt in recruiting disadvantaged families to a birth cohort study (2018)

Amit Arora, Narendar Manohar, Dina Bedros, Anh Phong David Hua, Steven Yu Hsiang You, Victoria Blight, Shilpi Ajwani, John Eastwood and Sameer Bhole

BioMed Central

In: BMC Nursing

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Publication Date: 2018-03-06

Description: Dental decay in early childhood can be prevented by a model based on shared care utilising members of primary care team such as Child and Family Health Nurses (CFHNs) in health promotion and early intervention...

Electronic ISSN: 1472-6955

Topics: Medicine

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70

Unknown

Impact of the introduction of an endotracheal tube attachment device on the incidence and severity of oral pressure injuries in the intensive care unit: a retrospective observational study (2018)

Jaye Hampson, Cameron Green, Joanne Stewart, Lauren Armitstead, Gemma Degan, Andrea Aubrey, Eldho Paul and Ravindranath Tiruvoipati

BioMed Central

In: BMC Nursing

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Publication Date: 2018-03-06

Description: Endotracheal tube (ETT) fasteners such as the AnchorFast™ claim to assist with the prevention of oral pressure injuries in intubated patients, however evidence to support their clinical efficacy is limited. Th...

Electronic ISSN: 1472-6955

Topics: Medicine

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71

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The short-term economic burden of gestational diabetes mellitus in Italy (2018)

Michela Meregaglia, Livia Dainelli, Helen Banks, Chiara Benedetto, Patrick Detzel and Giovanni Fattore

BioMed Central

In: BMC Pregnancy and Childbirth

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Publication Date: 2018-03-06

Description: The incidence of Gestational Diabetes Mellitus (GDM) is rising in all developed countries. This study aimed at assessing the short-term economic burden of GDM from the Italian healthcare system perspective.

Electronic ISSN: 1471-2393

Topics: Medicine

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72

Unknown

Adiponectin is required for maintaining normal body temperature in a cold environment (2018)

Qiong Wei, Jong Han Lee, Hongying Wang, Odelia Y. N. Bongmba, Chia-Shan Wu, Geetali Pradhan, Zilin Sun, Lindsey Chew, Mandeep Bajaj, Lawrence Chan, Robert S. Chapkin, Miao-Hsueh Chen and Yuxiang Sun

BioMed Central

In: BMC Physiology

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Publication Date: 2018-03-06

Description: Thermogenic impairment promotes obesity and insulin resistance. Adiponectin is an important regulator of energy homeostasis. While many beneficial metabolic effects of adiponectin resemble that of activated th...

Electronic ISSN: 1472-6793

Topics: Medicine

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73

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Salt hypersensitive mutant 9, a nucleolar APUM23 protein, is essential for salt sensitivity in association with the ABA signaling pathway in Arabidopsis (2018)

Kai-Chau Huang, Wei-Chih Lin and Wan-Hsing Cheng

BioMed Central

In: BMC Plant Biology

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Publication Date: 2018-03-06

Description: Although the nucleolus involves two major functions: pre-rRNA processing and ribosome biogenesis/assembly, increasing evidence indicates that it also plays important roles in response to abiotic stress. Howeve...

Electronic ISSN: 1471-2229

Topics: Biology

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74

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Correction to: Identification of tRNA nucleoside modification genes critical for stress response and development in rice and Arabidopsis (2018)

Youmei Wang, Chaoqun Pang, Xukai Li, Zhen Hu, Zhengyi Lv, Bo Zheng and Peng Chen

BioMed Central

In: BMC Plant Biology

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Publication Date: 2018-03-06

Description: Following publication of the original article [1], the authors reported that there was a mistake in the presentation of their funding information. The sentence “This study was supported by the National Natural...

Electronic ISSN: 1471-2229

Topics: Biology

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75

Unknown

Laparotomy in women with severe acute maternal morbidity: secondary analysis of a nationwide cohort study (2018)

Tom Witteveen, Athanasios Kallianidis, Joost J. Zwart, Kitty W. Bloemenkamp, Jos van Roosmalen and Thomas van den Akker

BioMed Central

In: BMC Pregnancy and Childbirth

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Publication Date: 2018-03-06

Description: Although pregnancy-related laparotomy is a major intervention, literature is limited to small case-control or single center studies. We aimed to identify national incidence rates for postpartum laparotomy rela...

Electronic ISSN: 1471-2393

Topics: Medicine

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76

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Petri net-based prediction of therapeutic targets that recover abnormally phosphorylated proteins in muscle atrophy (2018)

Jinmyung Jung, Mijin Kwon, Sunghwa Bae, Soorin Yim and Doheon Lee

BioMed Central

In: BMC Systems Biology

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Publication Date: 2018-03-06

Description: Muscle atrophy, an involuntary loss of muscle mass, is involved in various diseases and sometimes leads to mortality. However, therapeutics for muscle atrophy thus far have had limited effects. Here, we presen...

Electronic ISSN: 1752-0509

Topics: Biology

Published by BioMed Central

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77

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Risk assessment of occupational exposure to heavy metal mixtures: a study protocol (2018)

Fatma Omrane, Imed Gargouri, Moncef Khadhraoui, Boubaker Elleuch and Denis Zmirou-Navier

BioMed Central

In: BMC Public Health

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Publication Date: 2018-03-06

Description: Sfax is a very industrialized city located in the southern region of Tunisia where heavy metals (HMs) pollution is now an established matter of fact. The health of its residents mainly those engaged in industr...

Electronic ISSN: 1471-2458

Topics: Medicine

Published by BioMed Central

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78

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RNAseq analysis of bronchial epithelial cells to identify COPD-associated genes and SNPs (2018)

Jiyoun Yeo, Diego A. Morales, Tian Chen, Erin L. Crawford, Xiaolu Zhang, Thomas M. Blomquist, Albert M. Levin, Pierre P. Massion, Douglas A. Arenberg, David E. Midthun, Peter J. Mazzone, Steven D. Nathan, Ronald J. Wainz, Patrick Nana-Sinkam, Paige F. S. Willey, Taylor J. Arend…

BioMed Central

In: BMC Pulmonary Medicine

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Publication Date: 2018-03-06

Description: There is a need for more powerful methods to identify low-effect SNPs that contribute to hereditary COPD pathogenesis. We hypothesized that SNPs contributing to COPD risk through cis-regulatory effects are enrich...

Electronic ISSN: 1471-2466

Topics: Medicine

Published by BioMed Central

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79

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Pylorus drainage procedures in thoracoabdominal esophagectomy – a single-center experience and review of the literature (2018)

Stefan Fritz, Katharina Feilhauer, André Schaudt, Hansjörg Killguss, Eduard Esianu, René Hennig and Jörg Köninger

BioMed Central

In: BMC Surgery

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Publication Date: 2018-03-06

Description: Pylorotomy and pyloroplasty in thoracoabdominal esophagectomy are routinely performed in many high-volume centers to prevent delayed gastric emptying (DGE) due to truncal vagotomy. Currently, controversy remai...

Electronic ISSN: 1471-2482

Topics: Medicine

Published by BioMed Central

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80

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A prediction study of warfarin individual stable dose after mechanical heart valve replacement: adaptive neural-fuzzy inference system prediction (2018)

Huan Tao, Qian Li, Qin Zhou, Jie Chen, Bo Fu, Jing Wang, Wenzhe Qin, Jianglong Hou, Jin Chen and Li Dong

BioMed Central

In: BMC Surgery

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Publication Date: 2018-03-06

Description: It’s difficult but urgent to achieve the individualized rational medication of the warfarin, we aim to predict the individualized warfarin stable dose though the artificial intelligent Adaptive neural-fuzzy in...

Electronic ISSN: 1471-2482

Topics: Medicine

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81

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Nanog induced intermediate state in regulating stem cell differentiation and reprogramming (2018)

Peijia Yu, Qing Nie, Chao Tang and Lei Zhang

BioMed Central

In: BMC Systems Biology

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Publication Date: 2018-03-06

Description: Heterogeneous gene expressions of cells are widely observed in self-renewing pluripotent stem cells, suggesting possible coexistence of multiple cellular states with distinct characteristics. Though the elemen...

Electronic ISSN: 1752-0509

Topics: Biology

Published by BioMed Central

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82

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Crossed beaks in a local Swiss chicken breed (2018)

Sara Joller, Flurina Bertschinger, Erwin Kump, Astrid Spiri, Alois von Rotz, Daniela Schweizer-Gorgas, Cord Drögemüller and Christine Flury

BioMed Central

In: BMC Veterinary Research

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Publication Date: 2018-03-06

Description: Crossed beaks have been reported to occur in Appenzeller Barthuhn, a local Swiss chicken breed. The assumed causes for this beak deformity which are also seen in other bird species including domestic chickens,...

Electronic ISSN: 1746-6148

Topics: Medicine

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83

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Pathology of carbon monoxide poisoning in two cats (2018)

Arya Sobhakumari, Robert H. Poppenga, J. Brad Pesavento and Francisco A. Uzal

BioMed Central

In: BMC Veterinary Research

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Publication Date: 2018-03-06

Description: Carbon monoxide (CO), a common cause of poisoning in human beings has also been implicated in the death of animals. Though there are multiple studies on CO poisoning and relevant lethal blood COHb concentratio...

Electronic ISSN: 1746-6148

Topics: Medicine

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84

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What women say about their dysmenorrhea: a qualitative thematic analysis (2018)

Chen X. Chen, Claire B. Draucker and Janet S. Carpenter

BioMed Central

In: BMC Women's Health

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Publication Date: 2018-03-06

Description: Dysmenorrhea is highly prevalent and is the leading cause of absence from school and work among women of reproductive age. Evidence suggests that dysmenorrhea may also be a risk factor for other chronic pain c...

Electronic ISSN: 1472-6874

Topics: Medicine

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85

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Predictors of cervical cancer screening intention of HIV-positive women in the central region of Ghana (2018)

Nancy Innocentia Ebu and Joseph Kwesi Ogah

BioMed Central

In: BMC Women's Health

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Publication Date: 2018-03-06

Description: Cervical cancer affects women, especially those with HIV-positive status. This study hypothesised that more HIV-positive women with high cues about cervical cancer screening, high perceived susceptibility to c...

Electronic ISSN: 1472-6874

Topics: Medicine

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86

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The tyrosine kinase inhibitor nilotinib is more efficient than mitotane in decreasing cell viability in spheroids prepared from adrenocortical carcinoma cells (2018)

Elaine Silveira, Isadora Pontes Cavalcante, Jean Lucas Kremer, Pedro Omori Ribeiro de Mendonça and Claudimara Ferini Pacicco Lotfi

BioMed Central

In: Cancer Cell International

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Publication Date: 2018-03-06

Description: New drugs for adrenocortical carcinoma (ACC) are needed because most patients undergo rapid disease progression despite surgery and adjuvant therapy with mitotane. In this study, we aimed to investigate the in...

Electronic ISSN: 1475-2867

Topics: Medicine

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87

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Long non-coding RNA CASC2 improved acute lung injury by regulating miR-144-3p/AQP1 axis to reduce lung epithelial cell apoptosis (2018)

Hongbin Li, Huijuan Shi, Min Gao, Ning Ma and Rongqing Sun

BioMed Central

In: Cell and Bioscience

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Publication Date: 2018-03-06

Description: Apoptosis of lung epithelial cell is implicated in the pathogenesis of acute lung injury (ALI). To study the protective effect and mechanism of cancer susceptibility candidate 2 (CASC2) on reducing lung epithe...

Electronic ISSN: 2045-3701

Topics: Biology

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88

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Correlation between hepatic human males absent on the first (hMOF) and viral persistence in chronic hepatitis B patients (2018)

Liwen Chen, Chuanwu Zhu, Fengdi Li, Yun Wang, Rebecca Bao, Zhujun Cao, Xiaogang Xiang, Lei Yan, Lanyi Lin, Gangde Zhao, Qing Xie, Shisan Bao and Hui Wang

BioMed Central

In: Cell and Bioscience

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Publication Date: 2018-03-06

Description: Chronic hepatitis B (CHB) remains a global health dilemma with high morbidity and mortality. Human males absent on the first (hMOF) (a histone acetyltransferase) is responsible for DNA damage repair, tumorigen...

Electronic ISSN: 2045-3701

Topics: Biology

Published by BioMed Central

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