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Statistical modeling of RNA structure profiling experiments enables parsimonious reconstruction of structure landscapes
(2018)
Nature Publishing Group (NPG)
Publication Date:
2018-02-10
Description:
Statistical modeling of RNA structure profiling experiments enables parsimonious reconstruction of structure landscapes Statistical modeling of RNA structure profiling experiments enables parsimonious reconstruction of structure landscapes, Published online: 09 February 2018; doi:10.1038/s41467-018-02923-8 Different experimental and computational approaches can be used to study RNA structures. Here, the authors present a computational method for data-directed reconstruction of complex RNA structure landscapes, which predicts a parsimonious set of co-existing structures and estimates their abundances from structure profiling data.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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