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  • University Bibliography  (2,138)
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  • 1
    Book
    Book
    Cham : Springer International Publishing
    Keywords: Biologie allgemein ; C60 fullerene-chemotherapy ; Water-soluble drugs ; Nanocomplexes ; Physicochemical characteristics ; Anticancer activity in vitro
    Abstract: Noncovalent water-soluble nanocomplexes of C60 fullerene (C60) with chemotherapeutic drugs (Doxorubicin (Dox), Cisplatin (Cis), and herbal alkaloid Berberine (Ber)) were created. Their anticancer action toward various tumor cells was studied in vitro, addressing specifically their biological synergy, compared with the action of these drugs in the non-immobilized form. Different theoretical and experimental (SEM and AFM microscopy, UV-Vis, DLS, NMR and SANS spectroscopy, ITC calorimetry) methods were applied for getting insight into the nature of the nanocomplexes with drug molecules, as well as into the physical forces enabling stabilization of these complexes. Physicochemical mechanisms were proposed for drug interaction with C60. An enhancement of the toxic action of the created water-soluble C60-drug nanocomplexes toward cancer cells, compared to the action of free drug, was found. Specifically, the C60-Dox nanocomplexes demonstrated ~3.5 higher cytotoxic potential in the leukemic cell lines (CCRF-CEM, Jurkat, THP1, and Molt-16) in comparison with free Dox in the nanometer range of concentrations. Besides, C60 doubled the intracellular level of the up-taken Dox, which also evidenced its function as a nanocarrier. The toxic effect of C60-Cis nanocomplex toward Lewis lung carcinoma (LLC) cells was shown to be higher with IC50 values 3.3 and 4.5 times at 48 h and 72 h, respectively, as compared to the IC50 of free drug. 12.5 μМ Cis had no effect on LLC cells’ viability. The C60-Cis nanocomplex in Cis-equivalent concentration substantially decreased the viability of tumor cells, impaired their shape and adhesion, inhibited migration, and induced their accumulation in the pro-apoptotic sub-G1 phase of cell cycle. An induction of apoptosis by the C60-Cis nanocomplex was confirmed by the activation of caspase 3/7 and externalization of phosphatidylserine on the outer membrane of LLC cells after their double staining with the Annexin V-FITC/PI. The complexation with C60 promoted intracellular uptake of the Ber. An increase in C60 concentration in the C60-Ber nanocomplexes was accompanied by the elevation of their antiproliferative potential toward CCRF-CEM cells in the order: free Ber ˂ 1:2 ˂ 1:1 ˂ 2:1. These findings suggest a universal potential of water-soluble pristine C60 as a unique nano-platform for the delivery of the chemotherapeutic drugs in cytotoxic effect of these drugs.
    Type of Medium: Book
    Publication type: Anthology article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: English
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  • 2
    Book
    Book
    Honolulu, HI : University of Hawai'i at Manoa, Hamilton Library
    Keywords: Verwaltungswissenschaft allgemein
    Abstract: Despite substantial investments, data science has failed to deliver significant business value in many companies. So far, the reasons for this problem have not been explored systematically. This study tries to find possible explanations for this shortcoming and analyses the specific challenges in data-driven projects. To identify the reasons that make data-driven projects fall short of expectations, multiple rounds of qualitative semi-structured interviews with domain experts with different roles in data-driven projects were carried out. This was followed by a questionnaire surveying 112 experts with experience in data projects from eleven industries. Our results show that the main reasons for failure in data-driven projects are (1) the lack of understanding of the business context and user needs, (2) low data quality, and (3) data access problems. It is interesting, that 54% of respondents see a conceptual gap between business strategies and the implementation of analytics solutions. Based on our results, we give recommendations for how to overcome this conceptual distance and carrying out data-driven projects more successfully in the future.
    Type of Medium: Book
    Publication type: Anthology article
    Access type: Open Access
    Peer-reviewed: yes
    Language: English
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  • 3
    Book
    Book
    Weinheim : Wiley-VCH
    Keywords: Biologie allgemein
    Type of Medium: Book
    Publication type: Journal article
    Access type: Open Access
    Peer-reviewed: yes
    ISSN: 1521-3773
    Language: English
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  • 4
    Book
    Book
    Hannover : TIB Open Publishing
    Keywords: Maschinenbau allgemein ; Socio-Cyber-Physical Production Systems ; Limited Infrastructure ; Developing Countries ; Craft ; non-industrialized ; Digitalization
    Abstract: During the last decade production innovation was mainly focused on connectivity aspects. The vision of smart factories running on software, that uses collected machine data, has become true but foremost for leading industrial companies in highly developed countries. Apart from these, production can also be found in non-industrialized craft professions as well as in less developed countries. As digitalization does not necessarily require an industrial or developed setting the latter could possibly benefit from it as well. Socio-cyber-physical production systems have been used to describe the interdependencies of linked production systems but usually focus on highly developed regions as well as for industrial applications. This paper lines out similarities and differences for each case, introduces the concept of cyber-physical production systems (CPPS) and its extension to socio-CPPS (SCPPS), which emphasizes the role of human workers in the production environment. The relation between industrial, non-industrial production and innovations is examined. Furthermore, the widening of SCCPS concepts for non-industrial production is discussed.
    Type of Medium: Book
    Publication type: Anthology article
    Access type: Open Access
    Peer-reviewed: yes
    Language: English
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  • 5
    Book
    Book
    Amsterdam : Elsevier
    Keywords: Maschinenbau allgemein ; Fault diagnosis ; Chiller ; Domain adaptation ; Data-driven
    Abstract: Automatic fault diagnosis is becoming increasingly important for assessing a chiller’s degradation state and plays a key role in modern maintenance strategies. Data-driven approaches have already become well established for this purpose as they rely on historical data and are therefore more generally applicable compared to their model-based counterparts. Existing chiller fault diagnosis models, however, require labelled data from the target system, which are often not available. Therefore, in this paper, a data-driven fault diagnosis model is proposed that deploys domain adaptation techniques to enable the transfer of knowledge amongst heterogeneous chillers. In particular, the model utilizes transfer component analysis (TCA) and a support vector machine with adapting decision boundaries (SVM-AD) to diagnose faults by aggregating labelled source and unlabelled target domain data in the training phase. Furthermore, it is demonstrated how the model parameters can be tuned to ensure effective classification performance, which is then evaluated by use of fault data stemming from different chiller types. Experimental results show that with the proposed approach faults can be diagnosed with high accuracy for cases when labelled target domain data are not available.
    Type of Medium: Book
    Publication type: Journal article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: English
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  • 6
    Book
    Book
    Amsterdam : Elsevier
    Keywords: Maschinenbau allgemein
    Abstract: Polyurethane foam is one of the most versatile polymers widely used in the automotive industry. However, due to the rising amount of polyurethane foam waste in the environment, there is growing research attention focusing on circular economy solutions to closing the material loop. This study aimed to determine the possible changes in thermo-mechanical properties between rigid polyurethane prepared using polyols derived from depolymerization of commercial polyurethane foam with benchmark rigid polyurethane (Ben PU). Polyurethane foams containing dispersion polyol were reacted with dipropylene glycol (DPG) and diethylene glycol (DEG) with a ratio of DPG: DEG of 1:1 in the presence of a consumable catalyst (Di-n-butyl amine). The recovered polyol was used as a raw material replacing 100% benchmark rigid polyurethane petroleum-based polyester polyol to produce the recycled polyurethane (Rec PU). Thermal analysis was conducted to measure the recycled polyurethane's glass transition temperatures (Tg) using differential scanning calorimetry (DSC). Tensile strength, elastic modulus, toughness, and hardness test of the recycled polyurethane were conducted under three different temperatures; 24°C, 40°C, and 60°C. From the DSC results, the glass transition temperatures for the recycled and the benchmark rigid polyurethane occurred at 43°C and 50.4°C, respectively. Both polymers showed the brittle-ductile transition from 24°C to 40°C. Tensile strength for recycled polyurethane was lower than that of benchmark rigid polyurethane by 29-43% and a corresponding 24-50% decrease in elastic modulus. Recycled polyurethane recorded lower toughness than petroleum-based pure polyurethane by 13-16%. However, the recycled polymer recorded high shored D values than the benchmark rigid polyurethane by 9-29%. This study reveals that recycled polyol could be used as feedstock for polyurethane production with applications tailored to its mechanical properties.
    Type of Medium: Book
    Publication type: Journal article
    Access type: Open Access
    Peer-reviewed: yes
    Language: English
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  • 7
    Book
    Book
    Bellingham, WA : SPIE
    Keywords: Maschinenbau allgemein
    Type of Medium: Book
    Publication type: Journal article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: English
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  • 8
    Book
    Book
    Cham : Springer International Publishing
    Keywords: Verwaltungswissenschaft allgemein ; Local government ; Organisational structure ; Decentralisation ; Fiscal supervision ; Budget control
    Abstract: There is a general consensus on the effects of bureaucratic structures on task implementation and performance. Nonetheless, there has been very little research in the field of local public finance regulation. This article analyses the question of organisational structure in the field of local public finance regulation by surveying 18 European countries. We present five organisational dimensions, which potentially relate to regulatory outputs, and analyse their relation to four fiscal indicators. Those organisational dimensions are (1) the department owning the task of fiscal oversight, (2) centralised or decentralised implementation, (3) implementation in the form of one concentrated or several deconcentrated (regionalised) administrative units, (4) involvement of audit court(s) and (5) task execution by higher local government tiers. This analysis carefully demonstrates whether fiscal performance is somewhat more difficult for some organisational structures than for others. The number of countries per dimension shows that in the field of local public finance regulation, some options are more likely than other ones. Moreover, our results indicate that those organisational categories, such as “task ownership” and the involvement of “audit courts” link to higher financial performance. These results can help practitioners at the respective government levels to reconsider given bureaucratic structures.
    Type of Medium: Book
    Publication type: Anthology article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: German
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  • 9
    Book
    Book
    Cham : Springer International Publishing
    Keywords: Verwaltungswissenschaft allgemein ; Fiscal rules ; North Rhine-Westphalia ; Enforcement ; Responsive regulation ; Politics of enforcement
    Abstract: Despite the growing significance of fiscal rules, there is little research about tools and practices of enforcement at the local level. Addressing this knowledge gap, this chapter makes three contributions: first, we review the literature on regulatory enforcement in the ‘public-to-private’ context and discuss six key insights. Second, we provide an empirical overview of enforcement instruments across 21 European countries and discuss them in light of those key insights. Third, we present findings from an in-depth over-time analysis of enforcement practices in Germany’s largest state, North Rhine-Westphalia. We find that European supervisory bodies have a range of instruments that broadly follow the logic of the ‘enforcement pyramid’ at their disposal, but there is substantial cross-national variation in the instruments used. The case study reveals a ‘back and forth’ enforcement style alternating between strengthening and loosening rules and enforcement measures. We find political logics, regulators’ capacities and economic contexts as key drivers. Finally, we conclude that the idea of enforcement as a rational application of legal norms is unrealistic. In order to increase compliance, regulators should make more of an effort to understand the underlying rationale for compliance and violations; they need to secure political support and a credible strategy for escalating sanctions in case of non-compliance.
    Type of Medium: Book
    Publication type: Anthology article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: English
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  • 10
    Book
    Book
    Basel : MDPI
    Keywords: Maschinenbau allgemein
    Abstract: Polytetrafluoroethylene (PTFE), polyhexafluoropropylene (PHFP) and polychlorotrifluoroethylene (PCTFE) were heated to their decomposition temperature in a high vacuum. The emitted fragments passed an electron cloud, condensed on a substrate and formed fluoropolymer film. Growth rate of PTFE and PHFP films increased up to a factor five in the presence of the electron cloud. Mass spectrometry revealed changes in the mass spectra of fragments generated by thermal decomposition only and formed under electron activation. The observed changes were different for each fluoropolymer. Infrared spectroscopy (IRS) showed that the structure of the films was close to the structure of the bulk polymers. Atomic force microscopy (AFM) has revealed different morphologies of PTFE, PHFP and PCTFE films, suggesting a Volmer–Weber growth mechanism for PTFE and PHFP but a Frank-van der Merwe one for PCTFE. All films were smooth at nanoscale and transparent from ultraviolet to near-infrared region. Additional radio frequency (RF) plasma ignited in the emitted fragments at a low pressure increased mechanical characteristics of the films without losing their optical transparency and smoothness.
    Type of Medium: Book
    Publication type: Journal article
    Access type: Open Access
    Peer-reviewed: yes
    Language: English
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  • 11
    Book
    Book
    Uetikon : Trans Tech Publications
    Keywords: Maschinenbau allgemein ; Agar ; Biomaterial ; Bioprinting ; Gelatin ; Validation of Material Parameters
    Abstract: The current state of technology for 3D printing with biomaterials is based on the extrusion of viscous materials. Mostly, extrusion heads utilize pneumatic pressure systems or stepper motors to force the substrate onto a surface. These methods are well developed for high viscouse materials. However, processing low viscous liquids may cause leakages in the system. This could be solved by applying continuous extrusion. Additionally, in order to process gelable substrates, such as gelatine and agar, tempered print heads in combination with a multi stage tempering system are required to prevent the system from clogging. The ongoing work presented in this paper focuses on the development of an extrusion system, which should be able to process multiple viscosities of gelatine sequentially. In order to achieve this, several measurements to examine the properties, as well as the material parameters of different biomaterials are performed. In this process gel point, force resistance and elasticity are the factors of particularly interest. Due to their ability to gel and their availability, the most relevant biomaterials are gelatine and agar. Using this data, an extrusion system involving a peristaltic pump, a heated tube and a nozzle, has been developed. The next step envisaged is to calibrate the extruder based on the obtained data and finally to validate the printing process by printing simple geometric structures. Assuming that a positive evaluation is obtained, the printing system will be tested for printing first organic test structures from patient data using the examined biomaterials.
    Type of Medium: Book
    Publication type: Journal article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: English
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  • 12
    Book
    Book
    Berlin ; Heidelberg : Springer
    Keywords: Maschinenbau allgemein
    Abstract: One of the limiting factors of graphene integration into electronic, photonic, or sensing devices is the unavailability of large-scale graphene directly grown on the isolators. Therefore, it is necessary to transfer graphene from the donor growth wafers onto the isolating target wafers. In the present research, graphene was transferred from the chemical vapor deposited 200 mm Germanium/Silicon (Ge/Si) wafers onto isolating (SiO2/Si and Si3N4/Si) wafers by electrochemical delamination procedure, employing poly(methylmethacrylate) as an intermediate support layer. In order to influence the adhesion properties of graphene, the wettability properties of the target substrates were investigated in this study. To increase the adhesion of the graphene on the isolating surfaces, they were pre-treated with oxygen plasma prior the transfer process of graphene. The wetting contact angle measurements revealed the increase of the hydrophilicity after surface interaction with oxygen plasma, leading to improved adhesion of the graphene on 200 mm target wafers and possible proof-of-concept development of graphene-based devices in standard Si technologies.
    Type of Medium: Book
    Publication type: Journal article
    Access type: Open Access
    Peer-reviewed: yes
    Language: English
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  • 13
    Book
    Book
    Florida, USA : International Institute of Informatics and Systemics (IIIS)
    Keywords: Forschungsfelder der TH Wildau ; Angewandte Informatik ; Verwaltungswissenschaft allgemein ; Information Security Culture ; Awareness Raising ; SMEs ; Healthcare Sector ; Serious Games
    Abstract: How important is Information Security in pandemic times? With digital processes playing an increasing role in all areas of life, the growing phenomenon of cybercrime includes a broad spectrum of attack possibilities. The attackers have no regard for the pandemic—on the contrary, they have taken advantage of the situation and increased their attacks. Information security is a constant concern and cannot be trained using just one method on just one occasion. It must be assumed that the necessary security culture in a company, in an institution, and in an organization such as a hospital can only be achieved with the help of continuous discursive security processes and ongoing, practical awareness-raising measures employing an interactive mix of methods. Here, blame must be avoided and mindfulness promoted. Major challenges need to be overcome, especially in times of pandemic, which introduces considerable stress into all work situations. Information security and the pandemic situation must be understood in terms of their interaction in order to continuously improve the security culture.
    Type of Medium: Book
    Publication type: Anthology article
    Access type: Metadata only Access
    Peer-reviewed: yes
    ISBN: 978-1-950492-56-5
    Language: English
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  • 14
    Online Resource
    Online Resource
    Cham : Springer International Publishing
    Keywords: Verwaltungswissenschaft allgemein ; Fiscal decentralisation ; Regulation ; Local government
    Abstract: Although local governments are essential providers of public services and infrastructure across Europe, they ultimately depend on funding from higher levels of government. The clear relevance of local government finances necessitates effective regulation in order to ensure financial sustainability, but as of yet there has been hardly any comparative research regarding this particular topic. The 18 chapters contained in this volume bring together the work of 40 experts in the disciplines of political science, economics, and public administration research to approach the subject of local financial regulation in various scales and contexts across Europe. In this introductory chapter, we first outline key concepts such as fiscal decentralisation and regulation and briefly describe associated underlying theories and research. Secondly, we present comparative fiscal data to demonstrate the variance and trends of fiscal decentralisation across Europe. It also introduces the concept and components of regulatory regimes and develops the argument, that the effectiveness and outcome of fiscal regulation depends not only on the quality of individual components but also on the interactions of those components. We finally present the three guiding questions of this volume and provide a short overview of the chapters to follow.
    Type of Medium: Online Resource
    Publication type: Anthology article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: English
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  • 15
    Book
    Book
    London : Taylor & Francis
    Keywords: Biologie allgemein
    Abstract: The introduction of nucleic acid amplification techniques has revolutionized the field of medical diagnostics in the last decade. The advent of PCR catalyzed the increasing application of DNA, not just for molecular cloning but also for molecular based diagnostics. Since the introduction of PCR, a deeper understanding of molecular mechanisms and enzymes involved in DNA/RNA replication has spurred the development of novel methods devoid of temperature cycling. Isothermal amplification methods have since been introduced utilizing different mechanisms, enzymes, and conditions. The ease with which isothermal amplification methods have allowed nucleic acid amplification to be carried out has had a profound impact on the way molecular diagnostics are being designed after the turn of the millennium. With all the advantages isothermal amplification brings, the issues or complications surrounding each method are heterogeneous making it difficult to identify the best approach for an end-user. This review pays special attention to the various isothermal amplification methods by classifying them based on the mechanistic characteristics which include reaction formats, amplification information, promoter, strand break, and refolding mechanisms. We would also compare the efficiencies and usefulness of each method while highlighting the potential applications and detection methods involved. This review will serve as an overall outlook on the journey and development of isothermal amplification methods as a whole.
    Type of Medium: Book
    Publication type: Journal article
    Access type: Open Access
    Peer-reviewed: yes
    Language: English
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  • 16
    Online Resource
    Online Resource
    Wiesbaden, Germany : Springer Vieweg
    Keywords: Wirtschaftswissenschaften allgemein ; Künstliche Intelligenz ; Recruiting ; Anschreiben ; Clusteranalyse ; Neuronales Netz
    Abstract: Künstliche Intelligenz, soweit besteht Einigkeit, hat das Potenzial, auch administrative Jobs zu verändern. Während in vielen Bereichen der Forschung die Arbeiten zur Künstlichen Intelligenz eine relativ lange Tradition aufweisen, ist das Personalmanagement ein Gebiet, in dem sich erst seit wenigen Jahren mit dem Thema beschäftigt wird. Es gibt viele Vorschläge zum Einsatz von Künstlicher Intelligenz im Personalmanagement, aber es mangelt an konkreten empirischen Beispielen. Dieser Beitrag versucht, im Rahmen einer Pilotstudie mit drei kleinen Datensätzen einen konkreten Anwendungsfall zu exemplifizieren. Mittels der einfachen Clusteranalyse aus der Gruppe des unsupervised Learnings sowie eines neuronalen Netzes aus der Gruppe des supervised Learnings werden Bewerbungsanschreiben analysiert. Dabei kann in Abhängigkeit der Qualität und Größe des Datensatzes gezeigt werden, dass die Clusteranalyse über Dokument-Wort-Matrizen menschliche Urteilsgruppen signifikant replizieren und darüber hinaus die Menge der optimalen Urteilsgruppen bestimmen kann. So müssten Recruiter nur noch exemplarische Bewerbungen je ermittelter Urteilsgruppe ansehen, um die Güte der Gruppe festzulegen. Mit Hinzunahme des neuronalen Netzes konnte eine Performancesteigerung sowohl bei der Replikation der menschlichen Urteile als auch im Falle der optimalen Menge der Urteilsgruppen in Abhängigkeit der Anzahl der verwendeten versteckten Neuronen erreicht werden. Dies beschränkt sich allerdings auf das Trainingsdatenset. Insofern kann abschließend festgehalten werden, dass die Verwendung beider Methoden ein erfolgversprechender Ansatz zur Einführung von Künstlicher Intelligenz im Recruiting darstellt.
    Type of Medium: Online Resource
    Publication type: Anthology article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: German
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  • 17
    Book
    Book
    London : Taylor & Francis
    Keywords: Verwaltungswissenschaft allgemein ; Regional development ; regional convergence ; post-communist transition ; borders ; night lights
    Abstract: This paper studies regional economic development on the municipality-level in Poland and Germany along the Oder–Neisse border. We use high-quality satellite night-time light intensity data as an innovative and comparable measure to proxy for overall economic activity on both sides of the border consistently over a long period of time (1992–2012). We use descriptive heat maps as well as regression analysis to investigate two aspects: first, how far is the economic convergence along the Polish-German border? Second, what effect does the distance to the border have on economic activity as measured with light emissions? Our findings suggest that convergence in overall activity across the border has been complete. Polish municipalities that used to be economically much weaker have caught up with those on the German side of the Oder and the Neisse rivers. As regards the importance of distance, we highlight different results for Germany and Poland. While distance to the border never mattered significantly for German regions, Polish municipalities closer to the border used to be substantially worse off in the early 1990s but caught up with regions further to the east by the end of the period of our analysis.
    Type of Medium: Book
    Publication type: Journal article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: English
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  • 18
    Book
    Book
    Weinheim : Wiley-VCH
    Keywords: Maschinenbau allgemein
    Abstract: In the course of classical optics manufacturing glass components are in permanent direct contact with aqueous operating materials. Such contact leads to a certain absorption of water and hydrogenous compounds that may induce severe glass defects. In this contribution, absorption of hydrogen and other contaminants during grinding of glass was observed and qualitatively detected via laser‐induced breakdown spectroscopy. It is shown that hydrogen, calcium, magnesium, and carbon are implanted into the glass surface where the contaminant concentration increases over grinding time or contact time of the glass surface with water and the grinding tool, respectively. The contaminants hydrogen, calcium, and magnesium can be attributed to the water used as lubricant. In contrast, carbon most likely originates from wear debris of the used silicon carbide grinding pads. Several possible mechanisms that lead to such surface contamination of glasses during grinding – diffusion, accumulation in micro cracks as well as the formation of hydrated silica – are finally introduced.
    Type of Medium: Book
    Publication type: Journal article
    Access type: Open Access
    Peer-reviewed: yes
    Language: English
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  • 19
    Book
    Book
    San Francisco, Calif. : Public Library of Science (PLoS)
    Keywords: Biologie allgemein
    Abstract: Leishmaniasis is a vector-borne disease caused by protozoan parasites of the genus Leishmania. In Armenia visceral leishmaniasis (VL) is re-emerging since 1999 after a long break of 30 years, with 167 cases recorded until 2019. Molecular diagnosis of VL was implemented only in 2016, and the causative agent was identified as L. infantum. In the present study we expanded the investigation of the causative agent to a characterization at strain level and the identification of its phylogenetic position among the L. infantum genotypes circulating worldwide. This is the first study addressing genetic diversity and population structure of L. infantum in Armenia and in Transcaucasia. Armenia is an extremely interesting region due to its bio-geographic specificities e.g. the high number of different climates in this small mountainous country and the observed high diversity of sand fly species, part of which occurring in very high altitudes. Ecological niche modeling based on registered VL cases and sand fly vectors collected in active VL foci revealed that the risk of further spread of VL is very high due to climate change. Studies of this region should be expanded to enable targeted control measures.
    Type of Medium: Book
    Publication type: Journal article
    Access type: Open Access
    Peer-reviewed: yes
    Language: English
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  • 20
    Book
    Book
    Cham : Springer International Publishing
    Keywords: Wirtschaftswissenschaften allgemein ; Technology commercialization ; University-industry tech-transfer ; Academic spin-offs and startups ; Open innovation ; Organizational barriers ; Absorption costs of new technology ; Co-creational interaction ; Accelerator and incubation programs
    Abstract: This edited book presents research results that are relevant for scientists, practitioners and policymakers who engage in knowledge and technology transfer from different perspectives. Empirical and conceptual chapters present original approaches regarding the current practice and policies behind technology transfer. By providing analyses at the macro, meso and micro-level, the respective chapters demonstrate how technology is moving from various organizational contexts into new institutions and becoming a critical aspect for competitiveness.
    Type of Medium: Book
    Publication type: Anthology
    Access type: Metadata only Access
    Peer-reviewed: yes
    ISBN: 978-3-030-61477-5
    Series Statement: FGF Studies in Small Business and Entrepreneurship
    Language: English
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  • 21
    Book
    Book
    Wiesbaden : Springer Fachmedien Wiesbaden
    Keywords: Photonik ; Optische Technologien ; Laser ; Lasertechnik ; Technische Optik ; Optik ; Hochtechnologien ; Optoelektronik ; Optische Bauelemente ; Biophotonik ; Quantencomputer ; Optische Fasern ; Optische Kommunikation ; Optische Sensorik ; Optische Messtechnik
    Abstract: We are at the crossroads of a new epoch: the age of electronics is being replaced by the age of photonics. This book will introduce you to the fascinating development of photonics, avoiding complicated technical terminology and instead explaining the physical fundamentals in a clear way. Based on this, important developments such as the laser and its applications in industry, research and everyday life are described. Complicated physical properties and technical details are explained to the reader in an understandable way. This Springer essential is a translation of the original German 1st edition essentials, Photonik einfach erklärt by Patrick Steglich and Katja Heise, published by Springer Fachmedien Wiesbaden GmbH, part of Springer Nature in 2019.The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation. Springer Nature works continuously to further the development of tools for the production of books and on the related technologies to support the authors.
    Type of Medium: Book
    Publication type: Monograph
    Access type: Metadata only Access
    Peer-reviewed: yes
    ISBN: 978-3-658-32651-7
    Series Statement: essentials
    Language: English
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  • 22
    Book
    Book
    Wildau : Technische Hochschule Wildau
    Keywords: Verwaltungswissenschaft allgemein
    Abstract: Ein Projekt der Technischen Hochschule Wildau im Auftrag des FZI Forschungszentrum Informatik. Das Lernszenario zum Thema Social Engineering basiert auf der Idee eines im Projekt „Informationssicherheit für den Berufseinstieg (SecAware4job)“, das von der Horst Görtz Stiftung gefördert wurde, unvollendeten entwickelten Rollenspiels. Daraus entstanden nun drei Lernstationen, die den Perspektivwechsel zwischen Betroffenen und Social Engineers ermöglichen. Das komplette Szenario nennt sich »Social Engineering Theater (SET)«. »Security Risk Roulette (SRR)« wurde in Kooperation mit dem Unterauftragnehmer known_sense entwickelt und greift Elemente des populären Glücksspiels Roulette auf. Der Fokus liegt hier auf der Risikoeinschätzung und -bewertung mithilfe einer Risikomatrix sowie den Risikobehandlungsoptionen Akzeptanz, Reduktion, Vermeidung und Transfer. Zur Ergänzung und Vervollständigung der analogen Lernszenarien wurden zwei digitale Ergänzungen konzipiert und programmiert.
    Type of Medium: Book
    Publication type: Monograph
    Peer-reviewed: no
    ISBN: 978-3-9819225-2-3
    Language: German
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  • 23
    Book
    Book
    Wiesbaden, Germany : Springer Vieweg
    Person(s): Meyer, Stephan
    Keywords: Verwaltungswissenschaft allgemein ; Autonomes Fahren ; Datenethikkommission ; Explainable AI ; Haftung ; Regulierung ; Urheberrecht
    Abstract: Künstliche Intelligenz nimmt komplexe Bewertungen vor, auf deren Grundlage sie ohne menschliches Zutun Entscheidungen treffen oder technische Vorgänge auslösen kann. Derart autonome Entitäten stellen die Rechtsordnung vor Herausforderungen. Sie taugen selbst nicht als Träger von Verantwortung und von Rechten. Aus diesem Grunde hinterlassen sie juristische Zurechnungslücken, wenn sie den Menschen ersetzen. Eine innovationsverträgliche Schließung solcher Lücken wird der Gesetzgeber nur erzielen, wenn er auf eine verwendungsbereichsspezifische Regulierung von Künstlicher Intelligenz setzt. Für das autonome Fahren ist dies bereits zum Teil gelungen.
    Type of Medium: Book
    Publication type: Anthology article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: German
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  • 24
    Online Resource
    Online Resource
    Amsterdam : Elsevier
    Keywords: Verwaltungswissenschaft allgemein
    Abstract: This paper assesses the impact of public good provision on the spatial distribution of employment as predicted by a local labor market model that allows for commuting. Using local grammar school closures in East Germany after 2000 in a difference-in-differences estimation framework coupled with an entropy balancing strategy, we find that the school closures triggered a decline in the number of (employed) residents by 11%. The number of local employees, in contrast, decreases by just 5% as in-commuters do not respond to the school closures. Moreover, we find – as predicted – that the school closures reduce house prices and that the share of land used for housing declines, albeit only to a small extent.
    Type of Medium: Online Resource
    Publication type: Journal article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: English
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  • 25
    Book
    Book
    Cham : Springer International Publishing
    Keywords: Wirtschaftswissenschaften allgemein ; Maker movement ; Maker space ; University–industry interaction ; Open lab day ; Innovation camp ; Knowledge and technology transfer ; Third Mission
    Abstract: The maker movement is a technology-based and collaborative creative movement that uses rapid prototyping technologies to create objects and products in innovative ways. It focuses on the collaborative, creative development and realization of innovative ideas and their implementation in publicly accessible spaces. The steady growth of this movement has been facilitated by recent technological progress and the many new digital manufacturing possibilities that support low-threshold access to technology. This development is increasingly attracting the interest of universities. In this study, we present a framework for the different forms and formats of knowledge and technology transfer, respectively the Third Mission, as curated by a selected university-based maker space: the ViNN:Lab (Venture Innovation Lab) in Germany. We derived the framework from the exploration of different forms and formats of transfer activities in the maker space and the development of the number of users and user groups within a time frame of 6 years (2014–2019). Besides developing insights into the development of involved users and forms of usage, in this study, we also examine the following activities: (a) outreach activities, (b) practical interactions, and (c) research and development. As part of this case study, we briefly discuss how the ViNN:Lab enhances university–industry interaction, attracts new and even unexpected partners beside company partners, and how the ViNN:Lab acts as a space for the development of new ideas.
    Type of Medium: Book
    Publication type: Anthology article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: English
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  • 26
    Book
    Book
    Columbus, Ohio : American Chemical Society (ACS)
    Keywords: Biologie allgemein ; biophotovoltaics ; reduced graphene oxide (rGO) ; scalable template process ; spin-coating ; 3D electrode structure ; carbon material
    Abstract: Photobioelectrodes represent one of the examples where artificial materials are combined with biological entities to undertake semi-artificial photosynthesis. Here, an approach is described that uses reduced graphene oxide (rGO) as an electrode material. This classical 2D material is used to construct a three-dimensional structure by a template-based approach combined with a simple spin-coating process during preparation. Inspired by this novel material and photosystem I (PSI), a biophotovoltaic electrode is being designed and investigated. Both direct electron transfer to PSI and mediated electron transfer via cytochrome c from horse heart as redox protein can be confirmed. Electrode preparation and protein immobilization have been optimized. The performance can be upscaled by adjusting the thickness of the 3D electrode using different numbers of spin-coating steps during preparation. Thus, photocurrents up to ∼14 μA/cm2 are measured for 12 spin-coated layers of rGO corresponding to a turnover frequency of 30 e– PSI–1 s–1 and external quantum efficiency (EQE) of 0.07% at a thickness of about 15 μm. Operational stability has been analyzed for several days. Particularly, the performance at low illumination intensities is very promising (1.39 μA/cm2 at 0.1 mW/cm2 and −0.15 V vs Ag/AgCl; EQE 6.8%).
    Type of Medium: Book
    Publication type: Journal article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: English
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  • 27
    Book
    Book
    Hannover : TIB Open Publishing
    Keywords: Hydrogen ; Green Gas Supply ; Renewable Energy Sources
    Abstract: The fossil fuels used to provide energy, such as coal, crude oil and natural gas, are largely responsible for carbon dioxide emissions and other so-called greenhouse gases. Hydrogen gas (H2) can make a key contribution to decarbonization. It can be produced using various processes. Several processes are available to produce hydrogen, such as (i) steam reforming, (ii) cracking process or (iii) electrolysis. Depending on the source of origin, there is a distinction made between different “colours”. Gray, blue, turquoise, yellow and green hydrogen is avail­able, the latter made using Renewable Energies. However, items such as (i) possible variants of hydrogen, (ii) leading export countries or (iii) provision paths to be preferred in the future will be discussed in this paper.
    Type of Medium: Book
    Publication type: Anthology article
    Access type: Open Access
    Peer-reviewed: yes
    Language: English
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  • 28
    Book
    Book
    Würzburg : Julius-Maximilians-Universität Würzburg
    Person(s): Grebinyk, Anna
    Keywords: cancer ; drug delivery ; photodynamic therapy
    Type of Medium: Book
    Publication type: Monograph
    Access type: Open Access
    Peer-reviewed: no
    Language: English
    Dissertation note: Dissertation
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  • 29
    Book
    Book
    Florida, USA : International Institute of Informatics and Systemics (IIIS)
    Person(s): Scholl, Margit
    Keywords: Forschungsfelder der TH Wildau ; Verwaltungswissenschaft allgemein ; Information Security ; Health Sector ; E-Health ; Pandemic Situation ; Research Map
    Abstract: Based on extensive research of the literature on the current status of the health sector in Germany, the four spotlight areas of CRITIS, the pandemic situation, pandemic planning, and communication and learning are discussed in more detail in connection with information security. They may be used to create an integrative research map for holistic approaches in future research projects. With this in mind, the aim of this paper is to summarize aspects with a sound basis in the literature. The focus here is on general lessons learned from previous awareness-raising projects in information security.
    Type of Medium: Book
    Publication type: Anthology article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: English
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  • 30
    Book
    Book
    Wiesbaden : b.i.t. Verl.-GmbH
    Keywords: Bibliothekswesen ; Künstliche Intelligenz
    Abstract: Ist die Suche im Bibliothekskatalog ein Auslaufmodell? Oder die Frage sei erlaubt, unter welchen Bedingungen es Bibliotheken schaffen könnten, dass Nutzer/-innen die Erstsuche nach Informationen über sie laufen lassen? Das sind beispielhafte Fragen, die man sich angesichts gewonnener Erfahrungen aus bisherigen Innovationen stellen kann, aber ebenfalls mit Blick auf das, was Neues an Technologien sich auf dem Markt befindet und zunehmend viele Lebensbereiche durchdringt. Das Forschungsgebiet der Künstlichen Intelligenz (KI) ist in aller Munde und fordert von Informationseinrichtungen eine Antwort darauf, ob der Einsatz von KI-Technologien als weitere Facette der Automatisierung und Digitalisierung von Workflows und Service in Bibliotheken sinnvoll und hilfreich, und ob Engagement auf dieser Linie notwendig ist. Auch wenn sich Bibliotheken in ihrem steten Bemühen um Innovation mit ihrer Belegschaft und Leitungen noch differenziert bis reserviert zu KI bekennen, ist ein weiterer Verlauf der Entwicklungen gemäß dem chinesischen Sprichwort: Was du nicht aufhalten kannst, solltest du begrüßen, absehbar. Was heißt das aber für Bibliotheken, den Wandel zu gestalten bis hin zu dem Moment, wenn ein Dienst über die Pilot-, Prototyp- und damit Projektphase hinaus als fester Bestandteil des Serviceangebots fest etabliert und verstetigt werden soll? Welche Ressourcen und Kompetenzen sind z.B. in der Konsequenz von der Einrichtung selbst vorzuhalten? Weitere Fragen betreffen die Bewältigung der Masse an Daten und ihre Offenheit für die Anwendung von KI-Algorithmen.
    Type of Medium: Book
    Publication type: Journal article
    Access type: Open Access
    Peer-reviewed: yes
    Language: German
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  • 31
    Book
    Book
    Wiesbaden : b.i.t. Verl.-GmbH
    Keywords: Bibliothekswesen ; Künstliche Intelligenz
    Abstract: Ist der Suchschlitz ein Vintage Look&Feel des letzten Jahrhunderts? Oder - die Frage sei erlaubt, - unter welchen Bedingungen es Bibliotheken schaffen könnten, dass Nutzerinnen und Nutzer die Erstsuche nach Informationen über sie laufen lassen? Das sind beispielhafte Fragen, die man sich angesichts gewonnener Erfahrungen aus bisherigen Innovationen stellen kann, aber ebenfalls mit Blick auf das, was Neues an Technologien sich auf dem Markt befindet und zunehmend viele Lebensbereiche durchdringt. Das Forschungsgebiet der Künstlichen Intelligenz (KI) ist in aller Munde und fordert von Informationseinrichtungen eine Antwort darauf, ob der Einsatz von KI-Technologien als weitere Facette der Automatisierung und Digitalisierung von Workflows und Service in Bibliotheken sinnvoll und hilfreich, und ob Engagement auf dieser Linie notwendig ist. Auch wenn sich Bibliotheken in ihrem steten Bemühen um Innovation mit ihrer Belegschaft und Leitungen noch differenziert bis reserviert zu KI bekennen, ist ein weiterer Verlauf der Entwicklungen gemäß dem chinesischen Sprichwort "Was du nicht aufhalten kannst, solltest du begrüßen", absehbar. Was heißt das aber für Bibliotheken, den Wandel zu gestalten bis hin zu dem Moment, wenn ein Dienst über die Pilot-, Prototyp- und damit Projektphase hinaus als fester Bestandteil des Serviceangebots fest etabliert und verstetigt werden soll? Welche Ressourcen und Kompetenzen sind z.B. in der Konsequenz von der Einrichtung selbst vorzuhalten? Weitere Fragen betreffen die Bewältigung der Masse an Daten und ihre Offenheit für die Anwendung von KI-Algorithmen.
    Type of Medium: Book
    Publication type: Journal article
    Access type: Open Access
    Peer-reviewed: yes
    Language: German
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  • 32
    Book
    Book
    Berlin ; Heidelberg : Springer Spektrum
    Abstract: Dieses Lehrbuch hilft Ihnen, die typischen Einführungsvorlesungen zur Physik zu meistern. Denn Physik im Studium funktioniert anders als in der Schule. Die Formeln werden komplexer, das Tempo höher. Dieser Vorkurs liefert Ihnen verständlich aufbereitetes Physik-Grundwissen, das Sie für die ersten Semester brauchen. Schulstoff zu Themen aus der Mechanik, Thermodynamik, Elektrodynamik und der Optik wird wiederholt und vorsichtig vertieft. Mit mehr als 150 Beispielen und mehr als 50 Aufgaben inklusive Schritt-für-Schritt-Lösung plus Selbsttest „Fit fürs Studium?“ können Sie das Gelernte üben und überprüfen. Außerdem bereiten Sie Insider-Tipps vom erfahrenen Dozenten darauf vor, was an der Uni anders läuft, was Ihre Professor/-innen voraussetzen und wo Studierende häufig Fehler machen. Ein kleines Vokabelheft für typische Fachbegriffe schließt auch die letzte Verständnislücke.
    Type of Medium: Book
    Publication type: Monograph
    Access type: Metadata only Access
    Peer-reviewed: yes
    ISBN: 978-3-662-62126-4
    Language: German
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  • 33
    Book
    Book
    München : Beck
    Keywords: Rechtswissenschaften allgemein
    Type of Medium: Book
    Publication type: Journal article
    Access type: Metadata only Access
    Peer-reviewed: yes
    ISSN: 2703-0776
    Language: German
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  • 34
    Book
    Book
    Wiesbaden, Germany : Springer Vieweg
    Keywords: Wirtschaftswissenschaften allgemein ; Big Data ; Datenschutz ; Art. 22 DSGVO ; Automatisierte Entscheidungen im Einzelfall ; Profiling
    Abstract: Im April 2016 wurde die Europäische Datenschutz-Grundverordnung (DSGVO) nach jahrelangen Verhandlungen verabschiedet. Doch erst mit dem Ablauf der Übergangsfrist erlangte die DSGVO am 25. Mai 2018 ihre unmittelbare Geltung auch in Deutschland. Die Zielstellung des Unionsgesetzgebers, das europäische Datenschutzrecht zu harmonisieren und zu modernisieren, steht in Zeiten von allgegenwärtiger Automatisierung, Digitalisierung und Vernetzung vor immensen Herausforderungen. Die DSGVO begegnet dieser Entwicklung mit einer Regelung, die automatisierte Einzelfallentscheidungen grundsätzlich mit einem Verbot belegt. Die von der Datenverarbeitung betroffene Person soll somit vor den Auswirkungen einer Entscheidung geschützt werden, die ausschließlich auf der datengestützten Grundlage einer maschinenverantworteten Bewertung gefällt wird. Dieses Kapitel stellt den Regelungsinhalt des Art. 22 DSGVO und damit die automatisierten Entscheidungen im Einzelfall einschließlich dem Profiling dar. Insbesondere werden die Praxisrelevanz und die Wirksamkeit der Norm in Zeiten von Big Data untersucht, um zu bewerten, inwiefern die DSGVO die Risiken von maschinell gefällten Entscheidungen adressiert.
    Type of Medium: Book
    Publication type: Anthology article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: German
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  • 35
    Book
    Book
    Baden-Baden : Nomos
    Keywords: Verwaltungswissenschaft allgemein
    Type of Medium: Book
    Publication type: Journal article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: German
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  • 36
    Book
    Book
    Weinheim : Wiley-VCH
    Abstract: External stimuli are potent tools that Nature uses to control protein function and activity. For instance, during viral entry and exit, pH variations are known to trigger large protein conformational changes. In Nature, also the electron transfer (ET) properties of ET proteins are influenced by pH‐induced conformational changes. In this work, a pH‐controlled, reversible 310‐helix to α‐helix conversion (from acidic to highly basic pH values and vice versa) of a peptide supramolecular system built on a gold surface is described. The effect of pH on the ability of the peptide SAM to generate a photocurrent was investigated, with particular focus on the effect of the pH‐induced conformational change on photocurrent efficiency. The films were characterized by electrochemical and spectroscopic techniques, and were found to be very stable over time, also in contact with a solution. They were also able to generate current under illumination, with an efficiency that is the highest recorded so far with biomolecular systems.
    Type of Medium: Book
    Publication type: Journal article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: English
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  • 37
    Keywords: Wirtschaftswissenschaften allgemein ; Citizen science ; open science ; vignette survey
    Abstract: Citizen science has expanded rapidly over the past decades. Yet, defining citizen science and its boundaries remained a challenge, and this is reflected in the literature—for example in the proliferation of typologies and definitions. There is a need for identifying areas of agreement and disagreement within the citizen science practitioners community on what should be considered as citizen science activity. This paper describes the development and results of a survey that examined this issue, through the use of vignettes—short case descriptions that describe an activity, while asking the respondents to rate the activity on a scale from ‘not citizen science’ (0%) to ‘citizen science’ (100%). The survey included 50 vignettes, of which five were developed as clear cases of not-citizen science activities, five as widely accepted citizen science activities and the others addressing 10 factors and 61 sub-factors that can lead to controversy about an activity. The survey has attracted 333 respondents, who provided over 5100 ratings. The analysis demonstrates the plurality of understanding of what citizen science is and calls for an open understanding of what activities are included in the field.
    Type of Medium: Book
    Publication type: Journal article
    Access type: Open Access
    Peer-reviewed: yes
    Language: English
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  • 38
    Book
    Book
    Berlin ; Heidelberg : Springer
    Keywords: Biologie allgemein
    Abstract: The structure of complex cis-Pd(HLMe)Cl2 was studied both in solution and in solid state using multinuclear (1H, 13C, 15N) NMR spectroscopy and X-ray structural analysis. Complex was evaluated for cytotoxic activity. Thus, the results showed that cis-Pd(HLMe)Cl2 has a pronounced cytotoxicity toward human leukemic lymphoblast’s CCRF-CEM and cervix adenocarcinoma HeLa cells. Moreover, it was found that cis-Pd(HLMe)Cl2 is more toxic than cisplatin: its IC50 value at 24 h incubation was lower by more than an order for CCRF-CEM cells and by three orders for HeLa cells as compared with cisplatin IC50. Depending on the concentration, cis-Pd(HLMe)Cl2 is accelerated or slowed hemolysis of erythrocytes. Observed differential biological effects of cis-Pd(HLMe)Cl2 suggest the dependence of the agent’s interactions with cells on the molecular structure of palladium ligand and the cell type.
    Type of Medium: Book
    Publication type: Journal article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: English
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  • 39
    Book
    Book
    Suhlendorf : Bahn-Media
    Keywords: Maschinenbau allgemein ; Verkehrstechnik, Nautik allgemein
    Type of Medium: Book
    Publication type: Journal article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: German
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  • 40
    Book
    Book
    Amsterdam : Elsevier
    Keywords: Biologie allgemein ; Electrospinning ; Photosystem I ; Redox protein cytochrome c ; Photoelectrochemical signal
    Abstract: We describe the development of biohybrid electrodes constructed via combination of electrospun (e-spun) 3D indium tin oxide (ITO) with the trimeric supercomplex photosystem I and the small electrochemically active protein cytochrome c (cyt c). The developed 3D surface of ITO has been created by electrospinning of a mixture of polyelthylene oxide (PEO) and ITO nanoparticles onto ITO glass slides followed by a subsequent elimination of PEO by sintering the composite. Whereas the photosystem I alone shows only small photocurrents at these 3D electrodes, the co-immobilization of cyt c to the e-spun 3D ITO results in well-defined photoelectrochemical signals. The scaling of thickness of the 3D ITO layers by controlling the time (10 min and 60 min) of electrospinning results in enhancement of the photocurrent. Several performance parameters of the electrode have been analyzed for different illumination intensities.
    Type of Medium: Book
    Publication type: Journal article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: English
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  • 41
    Book
    Book
    Cambridge, MA : MIT Press
    Abstract: Citizen Science (CS) is a prominent field of application for Open Science (OS), and the two have strong synergies, such as: advocating for the data and metadata generated through science to be made publicly available [1]; supporting more equitable collaboration between different types of scientists and citizens; and facilitating knowledge transfer to a wider range of audiences [2]. While primarily targeted at CS, the EU-Citizen. Science platform can also support OS. One of its key functions is to act as a knowledge hub to aggregate, disseminate and promote experience and know-how; for example, by profiling CS projects and collecting tools, resources and training materials relevant to both fields. To do this, the platform has developed an information architecture that incorporates the public participation in scientific research (PPSR)—Common Conceptual Model①. This model consists of the Project Metadata Model, the Dataset Metadata Model and the Observation Data Model, which were specifically developed for CS initiatives. By implementing these, the platform will strengthen the interoperating arrangements that exist between other, similar platforms (e.g., BioCollect and SciStarter) to ensure that CS and OS continue to grow globally in terms of participants, impact and fields of application.
    Type of Medium: Book
    Publication type: Journal article
    Access type: Open Access
    Peer-reviewed: yes
    Language: English
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  • 42
    Book
    Book
    Cham : Springer International Publishing
    Abstract: The technical and socio-economic systems that surround us are complex, non-linear, so it is impossible to study these systems without using models that describe random processes. To expand approaches to the random processes study, we proposed the specific evaluation algorithm for the case of the set of values of an absolutely continuous random variable divided into intervals, in each of which the random variable undergoes the corresponding functional transformation described by definite probability function. The proposed algorithm consists of three steps – the limitation of data, calculation and obtaining the transformation estimates. Firstly, with algorithm’s help, there is an ability to evaluate the mathematical expectation change. Secondly, the influence of the probabilistic transformation of a random variable at every interval on expected value can be evaluated also. The algorithm is basic but, if necessary, it may be complicated in order to obtain estimates of k-th central moments changes. In addition, the algorithm is able to be the part of another one, used for identifying the distribution law of a random variable - the result of a probabilistic transformation. As an example of the proposed algorithm implementation, the process of technological replacement of jobs in the digital transformation of the economy is considered.
    Type of Medium: Book
    Publication type: Anthology article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: English
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  • 43
    Online Resource
    Online Resource
    Cham : Springer International Publishing
    Keywords: Wirtschaftswissenschaften allgemein ; Technology scouting ; Technology transfer ; Technology radar ; Lean method ; Digital tool ; Collaborative tool ; Open tool
    Abstract: Digitalization is a key driver throughout all drivers of change because its emerging and rapidly changing digital technologies lead to new products, services, and/or business models. Actors working in knowledge and technology transfer constantly have to keep up with the latest technological developments and cope with their enormous implications. To face these challenges, a variety of knowledge and technology transfer methods exist. This chapter provides an overview of these methods and illuminates the technology radar method as a potential digital tool for facilitating knowledge and technology transfer. Following the lean approach by Eric Ries, we document the process of the development of the technology radar. We present a web-based technology radar that is accessible to everyone on nearly any device, which encourages collaborative development. User testing with experts in the field of knowledge and technology transfer delivers insights and feedback for the further development of this digital tool. The results are conclusively discussed and then an outlook on the upcoming version of the technology radar, as well as different forms of usage in terms of knowledge and technology transfer, is provided.
    Type of Medium: Online Resource
    Publication type: Anthology article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: English
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  • 44
    Book
    Book
    Saarbrücken : Juris
    Keywords: Management und Recht ; Strafrecht ; Wirtschaftsrecht
    Type of Medium: Book
    Publication type: Journal article
    Access type: Metadata only Access
    Peer-reviewed: yes
    Language: German
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  • 45
    Book
    Book
    Basel : MDPI