Incorporation of decay-accelerating factor into the baculovirus envelope generates complement-resistant gene transfer vectors
Nature Publishing Group
Nature Archives 1869 - 2009
Process Engineering, Biotechnology, Nutrition Technology
[Auszug] Baculovirus vectors are an efficient means to deliver genes into hepatocytes in vitro. In experiments that exclude components of the complement system, gene transfer is facilitated. Therefore, the complement system has been defined to represent a potent primary barrier to direct application of ...
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